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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|DSP-0509||DSP 0509|DSP0509||DSP-0509 is a small molecule agonist of Toll-like receptor 7 (TLR7), which potentially inhibits tumor growth (Cancer Res July 1 2018 (78) (13 Supplement) 4726).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||osteosarcoma||not applicable||DSP-0509||Preclinical||Actionable||In a preclinical study, DSP-0509 inhibited tumor growth and reduced metastatic lung nodules in a syngeneic mouse model of osteosarcoma (Cancer Res July 1 2018 (78) (13 Supplement) 4726).||detail...|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT03416335||Phase Ib/II||DSP-0509 DSP-0509 + Pembrolizumab||A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile||Recruiting|