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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|AZ0108||AZ0108 is a PARP6 inhibitor, with additional activity against PARP1/2, which induces mitotic defects leading to apoptosis, and inhibits cell proliferation and tumor growth (PMID: 30297535).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||breast cancer||not applicable||AZ0108||Preclinical - Cell line xenograft||Actionable||In a preclinical study, AZ0108 induced mitotic defects, apoptosis, and inhibited growth in breast cancer cell lines in culture, and inhibited tumor growth in cell line xenograft models (PMID: 30297535).||30297535|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|