Therapy Detail

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Therapy Name Subasumstat
Synonyms
Therapy Description

Subasumstat (TAK-981) is a small molecule inhibitor of SUMO, which may lead to activation of anti-tumor immune response (Cancer Res 2019;79(13 Suppl):Abstract nr 3252).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Subasumstat TAK981|TAK 981|TAK-981 Subasumstat (TAK-981) is a small molecule inhibitor of SUMO, which may lead to activation of anti-tumor immune response (Cancer Res 2019;79(13 Suppl):Abstract nr 3252).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04065555 Phase I Avelumab + Subasumstat Cetuximab Cetuximab + Subasumstat Subasumstat Avelumab Intratumoral Microdosing of TAK-981 in Head and Neck Cancer Completed USA 0
NCT03648372 Phase I Subasumstat A Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Metastatic Solid Tumors or Lymphomas Recruiting USA 1


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