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Therapy Name | OBI-999 |
Synonyms | |
Therapy Description |
OBI-999 is an antibody-drug conjugate comprised of the Globo H antibody OBI-888 linked to monomethyl auristatin E, which delivers the anti-microtubule agent to Globo-H-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 36701651). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
OBI-999 | OBI999|OBI 999 | OBI-999 is an antibody-drug conjugate comprised of the Globo H antibody OBI-888 linked to monomethyl auristatin E, which delivers the anti-microtubule agent to Globo-H-expressing tumor cells, potentially resulting in decreased tumor growth (PMID: 36701651). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04084366 | Phase Ib/II | OBI-999 | Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors | Terminated | USA | 0 |