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|Therapy Name||LAM-003 + MK2206|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|LAM-003||LAM003|LAM 003||HSP90 Inhibitor 35||LAM-003 is a prodrug that is metabolized by esterases into the active HSP90 inhibitor drug, LAM-003A, which potentially induces cytotoxicity, and inhibits viability and tumor growth (PMID: 31751472).|
|MK2206||MK-2206|MK 2206||Akt Inhibitor (Pan) 21||MK2206 binds to and inhibits the activity of AKT in a non-ATP competitive manner, which may result in the inhibition of the PI3K/AKT signaling pathway and tumor cell proliferation (PMID: 20571069, PMID: 32194695).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|