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|Therapy Name||GSK690693 + LAM-003|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|GSK690693||GSK-690693||AKT Inhibitor (Pan) - ATP competitive 7||GSK690693 is a ATP-competitive pan-AKT inhibitor, which inhibits AKT signaling, resulting in decreased proliferation and increased apoptosis of tumor cells (PMID: 18381444, PMID: 31377021).|
|LAM-003||LAM003|LAM 003||HSP90 Inhibitor 35||LAM-003 is a prodrug that is metabolized by esterases into the active HSP90 inhibitor drug, LAM-003A, which potentially induces cytotoxicity, and inhibits viability and tumor growth (PMID: 31751472).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|