Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|MYCi975||NUCC-0200975||c-MYC Inhibitor 9||MYCi975 is an inhibitor of MYC that blocks the interaction between Myc and Max, which leads to reduced Myc stability, thereby potentially enhancing the antitumor immune response, and inhibiting colony formation and tumor growth (PMID: 31679823).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||lung carcinoma||not applicable||MYCi975||Preclinical||Actionable||In a preclinical study, MYCi975 treatment inhibited tumor growth in a mouse model of Lewis lung carcinoma (PMID: 31679823).||31679823|
|Unknown unknown||leukemia||not applicable||MYCi975||Preclinical - Cell culture||Actionable||In a preclinical study, MYCi975 treatment inhibited viability of a leukemia cell line in culture (PMID: 31679823).||31679823|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|