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|Therapy Name||CPI-637 + HY-16462|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|CPI-637||CPI637|CPI 637||CPI-637 is a CBP/p300 bromodomain inhibitor, which may have antitumor activity (PMID: 31000582).|
|HY-16462||HY16462|HY 16462||CDK9 Inhibitor 16||HY-16462 is a CDK9 inhibitor, which has potential antitumor activity (PMID: 31000582).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||triple-receptor negative breast cancer||not applicable||CPI-637 + HY-16462||Preclinical - Cell culture||Actionable||In a preclinical study, CPI-637 and HY-16462 treatment synergistically inhibited growth of a triple-negative breast cancer cell line in culture (PMID: 31000582).||31000582|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|