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Therapy Name | STM434 |
Synonyms | |
Therapy Description |
STM434 is a fusion protein comprising the extracellular domain of activin type II B receptor (ACVR2B) linked to a Fc chain that binds to activin-A and blocks activation of ACVR2B signaling, which potentially inhibits proliferation, survival and migration of activin-A overexpressing cancer cells (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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STM434 | STM 434|STM-434 | STM434 is a fusion protein comprising the extracellular domain of activin type II B receptor (ACVR2B) linked to a Fc chain that binds to activin-A and blocks activation of ACVR2B signaling, which potentially inhibits proliferation, survival and migration of activin-A overexpressing cancer cells (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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