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Therapy Name BB-1701
Synonyms
Therapy Description

BB-1701 is an antibody-drug conjugate (ADC) comprising an antibody targeting ERBB2 (HER2) conjugated to eribulin, which potentially induces cytotoxicity against tumor cells expressing ERBB2 (HER2) and leads to inhibition of tumor growth (Cancer Res (2023) 83 (7_Supplement): 1887).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BB-1701 BB 1701|BB1701 HER2 (ERBB2) Antibody 72 HER2 (ERBB2) Antibody-Drug Conjugate 27 BB-1701 is an antibody-drug conjugate (ADC) comprising an antibody targeting ERBB2 (HER2) conjugated to eribulin, which potentially induces cytotoxicity against tumor cells expressing ERBB2 (HER2) and leads to inhibition of tumor growth (Cancer Res (2023) 83 (7_Supplement): 1887).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06188559 Phase II BB-1701 A Study of BB-1701 in Previously Treated Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive or HER2-low Unresectable or Metastatic Breast Cancer Recruiting USA 0
NCT04257110 Phase I BB-1701 A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors Active, not recruiting USA 1


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