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Therapy Name | Anti-hCD70 CAR T cells |
Synonyms | |
Therapy Description |
Anti-hCD70 CAR T cells consist of patient-derived peripheral blood lymphocytes that have been transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) that targets CD70 and contains the extracellular region of CD27 fused to 41BB and CD3-zeta, which potentially inhibit the growth of CD70-expressing tumors (PMID: 27803044). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Anti-hCD70 CAR T cells | Anti-hCD70 CAR T cells consist of patient-derived peripheral blood lymphocytes that have been transduced with a retroviral vector expressing a chimeric antigen receptor (CAR) that targets CD70 and contains the extracellular region of CD27 fused to 41BB and CD3-zeta, which potentially inhibit the growth of CD70-expressing tumors (PMID: 27803044). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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