Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Therapy Name | SYN125 |
Synonyms | |
Therapy Description |
SYN125 is a monoclonal antibody targeting programmed cell death protein 1 (PD-1) that may lead to activation of T-cell-mediated immune response against tumor cells (NCI Thesaurus). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
SYN125 | SYN-125|SYN 125 | Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117 | SYN125 is a monoclonal antibody targeting programmed cell death protein 1 (PD-1) that may lead to activation of T-cell-mediated immune response against tumor cells (NCI Thesaurus). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT04363242 | Phase I | SYN125 SYN004 + SYN125 | A Study to Find the MTD of SYN125 in People With Solid Tumors and the MTD of SYN125 With a Fixed Dose of SYN004 in People in Patients With Epithelial Cancers With EGFR Expressions | Active, not recruiting | USA | 0 |