The Clinical Knowledgebase (CKB)

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CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 50 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.

Check out   CKB BOOST for content extending to 1800+ genes.

Sep 27, 2022 - Did you know CKB contains a large portion of preclinical evidence? Learn more about the different types of preclinical data CKB has to offer and how it can be used to help with your research and drug development in our latest blog post here. Interested in hearing more? Stay tuned for the next blog where we take a deeper dive into the preclinical data!

Sep 12, 2022 - Hello CKB users! Are you presenting a talk or poster at AMP 2022 that mentions CKB as a resource? If so, let us know! We would love to connect with you and promote your talk or poster at our JAX-CKB BOOTH #940! Feel free to e-mail us at

Jul 18, 2022 - Time for the next quarterly update to the CORE gene list! We are highlighting the tyrosine kinase genes this quarter. If you have any questions/comments, please feel free to reach out to us at!