The Clinical Knowledgebase (CKB)

Powered by The Jackson Laboratory

CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 85 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.

Not finding the content you need? Need more advanced searching?

Check out the CKB BOOST subscription version for content extending to 1,300+ genes.


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

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Jan 18, 2021 - Do you have a passion for science and precision medicine, but also love planning and executing projects within a business? Then look no further! The JAX-CKB team is looking for a highly motivated and innovative scientist to join the team: Clinical Scientific Curator

Jan 11, 2021 - We're looking for new people to join the JAX-CKB team! Check out the job listing here: Scientific Software Engineer