The Clinical Knowledgebase (CKB)

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CKB is a dynamic digital resource for interpreting complex cancer genomic profiles in the context of protein impact, therapies, and clinical trials. CKB CORE is the public access version we have been providing to the community since 2016. CKB CORE contains all the content associated with 50 genes that are commonly found on cancer hotspot panels. New and updated content is pushed out daily and viewable genes are available on a quarterly rotating schedule.

Check out   CKB BOOST for content extending to 1800+ genes.

Nov 19, 2021 - The CKB team is hiring! We're looking for part-time Clinical Content Curators to join the team---> Check out the job listing here!

Oct 12, 2021 - It's time for the next quarterly update to the CKB CORE gene list! This quarter we are highlighting tumor suppressor genes. For more information about the tumor suppressor genes available, check out the latest CKB CORE quarterly newsletter here. Have questions or comments? Email us at