Did you know you can find content related to TMB (tumor mutational burden), MSI (microsatellite instability), TILs (tumor infiltrating lymphocytes), and HRD (homologous repair deficiency) in CKB BOOST? Each biomarker can be found using 'Explore by Gene' or 'Explore by Variant'! Have questions or comments? Feel free to e-mail us at ckbsupport@jax.org.
It's time for the next quarterly update to the CKB CORE gene list! This quarter we will be highlighting the DNA repair genes again! Feel free to contact us at ckbsupport@jax.org with any questions or comments.
2022
March
CKB BOOST update! You can now find clinical trials for select countries other than the US and Canada. The list currently includes France, Germany, Spain, Italy, Austria, and Belgium. Have questions or comments on how to best search for clinical trials? Email us at ckbsupport@jax.org!
2022
February
NEW FEATURES in CKB BOOST! Want to quickly assess whether your variant is a polymorphism or results in transforming activity? Check out the Gene Variant Detail pages, which now include indicators for Polymorphism and Transforming Activity! Questions or comments? Contact us at ckbsupport@jax.org.
2022
January
It's time for the next quarterly update to the CKB CORE gene list! This quarter we are highlighting genes relevant to immuno-oncology. For more information about the genes available, check out the latest CKB CORE quarterly newsletter here. Have questions or comments? Email us at ckbsupport@jax.org
2021
January
We're looking for new people to join the JAX-CKB team! Check out the job listing here: Scientific Software Engineer
Exciting news! CKB CORE and BOOST now include clinical trial locations and contact details! Need more information or have questions? Email us at ckbsupport@jax.org.
2020
September
CKB UPDATE! CORE and BOOST now include transcripts with version numbers. Questions? Feel free to contact us at ckbsupport@jax.org.
2020
July
New FDA approval for Atezolizumab plus Cobimetinib and Vemurafenib for patients with BRAF V600-positive advanced melanoma! Find more information on this in CKB CORE. Need up-to-date information on other FDA drug approvals? Consider a CKB BOOST subscription, which includes full access to all drugs and their FDA approvals, along with related content!
2020
February
Check out this recent article to learn how CKB can be your genomic digital encyclopedia of cancer! Mainstreaming Precision Oncology
2020
January
CKB CORE now offers content for RSPO3, POLE, FANCA, and DOT1L, but removes EGFR, PTEN, TP53, and MET. However, these genes are always accessible with a CKB BOOST subscription!
2019
October
Have a question about CKB or want to learn more about it? Then check out The Scoop on CKB!
2019
September
We're looking for new people to join the CKB team! Check out the job listing here: Clinical Scientific Curator
2019
July
CKB BOOST now has AMP/CAP/ASCO evidence level coding!
2018
November
Vitrakvi (larotrectinib) approved regardless of tumor type for NTRK fusions, except with acquired resistance mutations! Need a list of resistance mutations? Visit ckbhome.jax.org and sign-up for CKB BOOST.
Barriers preventing the adoption of comprehensive cancer genomic profiling in the clinic (PMID: 28402162). Limited free copies available; request your copy at ckbsupport@jax.org.