Toggle navigation
CORE
News
Genes
Drug Classes
About
Disclaimer
Contact
Help
Category Variants
Navigation Legend
Glossary of Terms
Curation Methodology
Tutorial
FAQs
CKB CORE Quarterly News
CKB Drug Classes
ABL Inhibitor (pan)
9
ABL1 Inhibitor
7
Adenosine Targeting
22
Akt Inhibitor (Pan)
21
AKT Inhibitor (Pan) - ATP competitive
7
Akt1 Inhibitor
6
Akt2 Inhibitor
2
ALK Inhibitor
31
Antibiotic Antineoplastic
1
Antifungal Agent
1
Antimicrotubule Agent
14
Antisense Therapy
13
Aromatase Inhibitor
3
ATM Inhibitor
11
ATR Inhibitor
15
AURK Inhibitor (Pan)
12
Aurka Inhibitors
25
Aurkb Inhibitors
21
Aurkc Inhibitors
3
AXL Antibody
5
AXL Inhibitor
29
BCL-XL inhibitor
14
BCL2 Family Inhibitor
6
BCL2 inhibitor
26
BCL6 Inhibitor
3
BCR-ABL Inhibitor
29
BET Inhibitor (Pan)
32
BIRC5 Inhibitor
1
BRAF Inhibitor
23
BRD2 Inhibitor
1
BRD3 Inhibitor
2
BRD4 Inhibitor
10
BTK inhibitor
34
c-MYC Inhibitor
11
CBP/p300 inhibitor
11
CCR8 Antibody
6
CD19 Antibody
18
CD20 Antibody
18
CD22 Immune Cell Therapy
11
CD276 Antibody
8
CD3 Antibody
78
CD33 Antibody
11
CD37 Antibody
8
CD38 Antibody
17
CD39 Antibody
4
CD40 Antibody
13
CD47 Antibody
27
CD73 Antibody
11
CD74 Antibody
3
CDK Inhibitor (Pan)
3
CDK1 Inhibitor
13
CDK2 Inhibitor
26
CDK2/4 Inhibitor
0
CDK4 Inhibitor
16
CDK4/6 Inhibitor
13
CDK5 Inhibitor
8
CDK6 Inhibitor
6
CDK7 Inhibitor
15
CDK8 Inhibitor
5
CDK9 Inhibitor
20
Chemotherapy - Alkylating
16
Chemotherapy - Anthracycline
13
Chemotherapy - Antimetabolite
14
Chemotherapy - Platinum
7
Chemotherapy - Taxane
2
CHK Inhibitor (Pan)
2
CHK1 Inhibitor
17
CHK2 Inhibitor
7
CLDN18.2 Antibody
13
CRAF Inhibitor
11
CSF1 Antibody
2
CSF1R Antibody
4
CSF1R Inhibitor
28
CTLA4 Antibody
25
CTLA4 Inhibitor
4
CTNNB1 Inhibitor
26
CXCR Antagonist
4
CXCR4 Inhibitor
15
DDR1 Inhibitor
9
DDR2 inhibitor
7
DLL4 Antibody
7
DNA_PK Inhibitor
7
DNMT inhibitor (Pan)
5
DNMT1 inhibitor
4
DOT1L Inhibitor
3
DYRK1A Inhibitor
4
DYRK1B Inhibitor
3
EGFR Antibody
46
EGFR Immune Cell Therapy
3
EGFR Inhibitor (Pan)
58
EGFR Inhibitor 1st gen
3
EGFR Inhibitor 2nd gen
5
EGFR Inhibitor 3rd gen
24
EGFR Inhibitor 4th gen
12
EHMT2 Inhibitor
5
EPHB4 Inhibitor
6
ERK Inhibitor (pan)
18
ERK1 Inhibitor
3
ERK2 Inhibitor
3
EZH1 inhibitor
4
EZH2 inhibitor
19
FAK inhibitor
15
Farnesyltransferase Inhibitor
3
FASN Inhibitor
5
FGFR Inhibitor (Pan)
25
FGFR1 Inhibitor
27
FGFR2 Antibody
3
FGFR2 Inhibitor
22
FGFR3 Antibody
3
FGFR3 Inhibitor
19
FGFR4 Antibody
1
FGFR4 Inhibitor
8
FLT3 Antibody
4
FLT3 Inhibitor
62
FOLR1-targeted Therapy
18
Gamma secretase inhibitor
13
GITR Antibody
6
GLI1/2 inhibitor
6
Glutaminase Inhibitor
3
GPC3 Antibody
3
GR Antagonist
2
GSK-3alpha Inhibitor
1
GSK-3beta Inhibitor
4
GSK3 Inhibitor (Pan)
3
HDAC Inhibitor
42
HER inhibitor (Pan)
6
HER2 (ERBB2) Antibody
60
HER2 (ERBB2) Antibody-Drug Conjugate
24
HER2 (ERBB2) Immune Cell Therapy
3
HER2 (ERBB2) Vaccine
12
HER2 Inhibitor
39
HER3 (ERBB3) Antibody
21
HER3 Inhibitor
1
HGF Antibody
4
HIF2A Inhibitor
6
Hormone - Anti-androgens
41
Hormone - Anti-estrogens
25
Hormone - Anti-progestins
6
Hormone Antineoplastics
5
HRAS Inhibitor
1
HSP90 Inhibitor
35
IDH Inhibitor (Pan)
3
IDH1 Inhibitor
8
IDH2 Inhibitor
5
IDO1 Inhibitor
12
IGF-1R Inhibitor
17
IGF1/2 Antibody
2
IGF1R Antibody
8
Immune Checkpoint Inhibitor
146
IRAK1/4 Inhibitor
2
IRAK4 Inhibitor
6
JAK Inhibitor (Pan)
9
JAK Inhibitor (Pan) - ATP competitive
3
JAK1 Inhibitor
9
JAK1 Inhibitor - ATP competitive
5
JAK2 Inhibitor
16
JAK2 Inhibitor - ATP competitive
15
JAK3 Inhibitor
6
JAK3 Inhibitor - ATP competitive
4
JNK Inhibitor
5
KDM1A Inhibitor
15
KDM4 Inhibitor
4
KIT Inhibitor
56
KRAS G12C inhibitor
29
KRAS G12D Inhibitor
7
KRAS Inhibitor
10
LAG3 Antibody
18
LCK Inhibitor
6
LYN Inhibitor
3
MAP4K1 Inhibitor
6
MCL1 Inhibitor
18
MDM2 Inhibitor
21
MDM4 inhibitor
8
MEK inhibitor (Pan)
23
MEK1 Inhibitor
25
MEK2 Inhibitor
23
MEN1-KMT2A Inhibitor
6
MERTK Antibody
1
MERTK Inhibitor
13
MET Antibody
25
MET Immune Cell Therapy
1
MET Inhibitor
57
Microbiome
5
MNK1 Inhibitor
0
MNK1/2 Inhibitor
3
MNK2 Inhibitor
0
MPS1 Inhibitor
27
MSLN Antibody
7
mTOR Inhibitor
51
mTORC1 Inhibitor
9
mTORC2 Inhibitor
2
MUC16 Targeted Therapy
8
NOTCH Inhibitor (Pan)
5
NOTCH1 Antibody
2
NOTCH1 Inhibitor
0
NOTCH2 Antibody
3
NOTCH2 Inhibitor
0
NOTCH3 Antibody
2
OX40 Antibody
13
p38 MAPK Inhibitor (Pan)
3
p38-alpha Inhibitor
1
p53 Activator
11
p53 Gene Therapy
4
p53 Inhibitor
0
p53 Vaccine
5
PAK1 Inhibitor
11
PARP Inhibitor (Pan)
28
PARP-1 Inhibitor
6
PARP-2 Inhibitor
1
PD-L1 Inhibitor
12
PD-L1/PD-1 antibody
107
PDGFR Inhibitor (Pan)
28
PDGFR-alpha Inhibitor
10
PDGFR-beta Inhibitor
14
PDGFRA Antibody
2
PDK-1 Inhibitor
1
PDPK1 Inhibitor
10
PI3K Inhibitor (Pan)
40
PIK3CA inhibitor
21
PIK3CB inhibitor
8
PIK3CD inhibitor
26
PIK3CG inhibitor
9
PIM Inhibitor (Pan)
9
PIM1 Inhibitor
2
PIM3 Inhibitor
1
PKA Inhibitor
2
PKC alpha Inhibitor
6
PKC beta Inhibitor
6
PKC Inhibitor (Pan)
11
PLK1 Inhibitor
18
PP2A Activator
7
PP2A Inhibitor
2
PPM1D Inhibitor
3
PRMT5 Inhibitor
14
PSMA Antibody
16
RAD51 Inhibitor
4
RAF Inhibitor (Pan)
24
RAS Inhibitor (Pan)
8
RET Inhibitor
50
RON Inhibitor
11
ROR1 Antibody
5
ROS1 Inhibitor
20
S6 Kinase Inhibitor
5
SHP2 Inhibitor
19
SIRT1 Activator
3
SIRT1 Inhibitor
5
SIRT2 Inhibitor
5
SIRT3 Inhibitor
1
SMAC Mimetic
8
SMO Inhibitor
16
SMYD3 Inhibitor
3
SOS1 Inhibitor
9
SRC Inhibitor
31
STAT1 Inhibitor
0
STAT3 Inhibitor
25
STAT5 Inhibitor
4
STING1 Agonist
17
SYK Inhibitor
15
Tankyrase Inhibitor
11
TGFB (Pan) Antibody
5
TGFB inhibitor
5
TGFB2 Vaccine
1
TGFBR inhibitor (pan)
2
TGFBR1 inhibitor
16
TGFBR2 Antibody
2
TGFBR2 inhibitor
1
TIE2 Inhibitor
3
TIGIT Antibody
19
TIM-3 Antibody
8
TLR Antibody
0
TLR4 Agonist
2
TLR7 Agonist
9
TLR8 Agonist
7
TLR9 Agonist
9
TNFRSF17 Antibody
14
TNFRSF9 Antibody
24
TNK2 Inhibitor
6
TOPO Inhibitor (Pan)
3
TOPO1 inhibitor
10
TOPO2 inhibitor
5
Trk Receptor Inhibitor (Pan)
31
TrkA Receptor Inhibitor
8
TROP2 Antibody
6
TYRO3 Inhibitor
8
USP1 inhibitor
4
USP7 Inhibitor
4
VEGF Antibody
10
VEGFA Antibody
3
VEGFR Inhibitor (Pan)
35
VEGFR1 Inhibitor
5
VEGFR2 Antibody
4
VEGFR2 Immune Cell Therapy
1
VEGFR2 Inhibitor
36
VEGFR3 Antibody
1
VEGFR3 Inhibitor
6
VSIR Antibody
5
WEE1 Inhibitor
5
WNT Inhibitor
15
YAP Inhibitor
3
YES Inhibitor
3