Drug Class Detail

Drug Class Chemotherapy - Platinum


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Drug Name Trade Name Synonyms Drug Classes Drug Description
Cisplatin Platinol CDDP Chemotherapy - Platinum 6 Platinol (cisplatin) is a platinum based chemotherapeutic, which is FDA approved for bladder, ovarian, and testicular cancers (NCI Drug Dictionary).
NC-4016 DACH-platin micelle NC-4016|DACH-Pt/m NC-4016 Chemotherapy - Platinum 6 NC-4016 is comprised of polymeric micellar nanoparticles of 1,2-diaminocyclohexane platinum, which cause cross-linking of DNA leading to apoptosis (NCI Drug Dictionary).
NC-6004 Nanoplatin Chemotherapy - Platinum 6 NC-6004 comprises the platinum-based chemotherapeutic cisplatin incorporated into polymeric micellar nanocarriers, which may inhibit tumor growth (PMID: 16222314, PMID: 18406004).
Carboplatin Paraplatin CBDCA Chemotherapy - Platinum 6 Paraplatin (carboplatin) is a second-generation platinum compound and is activated intracellularly to form reactive platinum complexes that cross link DNA with DNA and with proteins. This induces apoptosis and inhibits cell growth (NCI Drug Dictionary).
Oxaliplatin Eloxatin Diaminocyclohexane Oxalatoplatinum Chemotherapy - Platinum 6 Eloxatin (oxaliplatin) is comprised of a platinum complex, which causes DNA-platinum cross-links, inhibition of DNA replication and transcription, and cell toxicity (NCI Drug Dictionary). Eloxatin (oxaliplatin) is FDA approved for colorectal cancer (FDA.gov).
PT-112 Chemotherapy - Platinum 6 PT-112 is a phosphoplatin that may result in decreased tumor cell growth (PMID: 19020081).
Molecular Profile Protein Effect Treatment Approaches