Drug Class Detail

Drug Class Hormone Antineoplastics

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Gonadorelin Dirigestran|GnRH|LHRHA|AY-24031 Hormone Antineoplastics 5 Gonadorelin is a synthetic version of gonatotropin-releasing hormone (GnRH) that binds GnRH receptors and induces gonatotropic hormone release, and leads to down-regulation of GnRH receptor expression and reduced hormone release following sustained exposure (NCI Drug Dictionary).
Z-endoxifen HCl Hormone Antineoplastics 5 Z-endoxifen HCl is the active metabolite of tamoxifen, which competitively inhibits estradiol binding to estrogen receptors (ER), thereby inhibiting growth of ER-positive tumors (PMID: 26232141).
Raloxifene Evista LY-139481 Hormone Antineoplastics 5 Evista (raloxifene) is a selective estrogen receptor modulator (SERM), which can act as an estrogen antagonist (NCI Drug Dictionary). Evista (raloxifene) is FDA approved for breast cancer (FDA.gov).
Tamoxifen Nolvadex ICI-46474 Hormone Antineoplastics 5 Nolvadex (tamoxifen) is a selective estrogen receptor modulator (SERM), which decreases DNA synthesis and cell growth (NCI Drug Dictionary). Nolvadex (tamoxifen) is FDA approved for breast cancer (FDA.gov).
Toremifene Fareston Acapodene Hormone Antineoplastics 5 Fareston (toremifene) is a selective estrogen receptor modulator (SERM), which acts as an estrogen antagonist (NCI Drug Dictionary). Fareston (toremifene) is FDA approved for metastatic breast cancer (FDA.gov).
Molecular Profile Protein Effect Treatment Approaches