Drug Class Detail

Drug Class CSF1R Antibody

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Cabiralizumab FPA008|BMS-986227 CSF1R Antibody 3 Cabiralizumab (FPA008) is a monoclonal antibody that targets the ligand-binding domain of CSF1R (PMID: 26051995).
LY3022855 anti-CSF-1R monoclonal antibody IMC-CS4|IMC-CS4 CSF1R Antibody 3 LY3022855 (IMC-CS4) is a monoclonal antibody against colony stimulating factor 1 receptor (CSF1R), which potentially induces antibody-dependent cell-mediated cytotoxicity (ADCC) in tumor cells over expressing CSF1R (NCI Drug Dictionary).
AMG 820 CSF1R Antibody 3 AMG 820 is a monoclonal antibody that binds CSF1R and prevents ligand binding, potentially resulting in decreased growth of CSF1-driven tumor cells (Cancer Res May 1, 2009 69; 2077).
Molecular Profile Protein Effect Treatment Approaches