Drug Class Detail

Drug Class FGFR2 Antibody

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Drug Name Trade Name Synonyms Drug Classes Drug Description
FPA144 Bemarituzumab FGFR2 Antibody 3 Bemarituzumab (FPA144) is a monoclonal antibody against FGFR2 isoform B, which prevents ligand interaction and induces cell mediated cytotoxicity, potentially inhibiting proliferation and promoting apoptosis in cancer cells expressing FGFR2 isoform B (J Clin Oncol 32, 2014 (suppl; abstr e15074).
BAY1179470 BAY 1179470 FGFR2 Antibody 3 BAY1179470 is an FGFR2 monoclonal antibody, which causes receptor internalization and degradation, thereby possibly inhibiting proliferation and promoting apoptosis in cancer cells (NCI Drug Dictionary, Cancer Res October 1, 2014 74; DDT02-01).
BAY1187982 FGFR2-ADC FGFR2 Antibody 3 BAY1187982 is an FGFR2 antibody conjugated to a toxin, which may promote apoptosis and inhibit tumor growth (NCI Drug Dictionary).
Molecular Profile Protein Effect Treatment Approaches
FGFR2 amp no effect FGFR Inhibitor (Pan) FGFR2 Antibody FGFR2 Inhibitor