Drug Class Detail

Drug Class GSK-3beta Inhibitor

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Drug Name Trade Name Synonyms Drug Classes Drug Description
PHA-533533 CDK1 Inhibitor 12 CDK2 Inhibitor 16 CDK4 Inhibitor 12 CDK5 Inhibitor 6 GSK-3beta Inhibitor 3 PHA-533533 is an inhibitor of CDK1, CDK2, CDK4, CDK5, and GSK3B, which inhibits phosphorylation of downstream targets and may promote cell cycle arrest and apoptosis in cancer cells (PMID: 15828833, PMID: 24004674).
PBA2 BCR-ABL Inhibitor 23 GSK-3beta Inhibitor 3 PBA2 is a dual BCR-ABL and GSK3-beta inhibitor that inhibits tumor cell growth (AACR, Cancer Res: April 2016; Volume 57, Abstract #3915).
Ro 31-8220 Ro-31-8220|Ro 318220 GSK-3beta Inhibitor 3 PKC Inhibitor (Pan) 9 Ro 31-8220 is a pan-protein kinase C (PKC) inhibitor, with additional activity against additional kinases including GSK3-beta, which may increase apoptosis and decrease growth of tumor cells (PMID: 8373348, PMID: 10998351, PMID: 18281471).
Molecular Profile Protein Effect Treatment Approaches