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NCT ID NCT02039726
Title (QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive
Recruitment Completed
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Daiichi Sankyo Inc.
Indications

acute myeloid leukemia

Therapies

Cytarabine + Fludarabine

Cytarabine + Etoposide + Mitoxantrone

Quizartinib

Filgrastim + Idarubicin

Age Groups: senior | adult
Covered Countries USA | CAN

Facility Status City State Zip Country Details
City of Hope National Medical Center Duarte California 91010 United States Details
University of Southern California, Norris Comprehensive Cancer Center Los Angeles California 90033 United States Details
UCLA Medical Center Los Angeles California 90095 United States Details
UC Davis Cancer Center Sacramento California 95817 United States Details
Stanford University Medical Center Stanford Comprehensive Cancer Center Stanford California 94305 United States Details
Yale University New Haven Connecticut 06520 United States Details
Emory Winship Cancer Institute Atlanta Georgia 30322 United States Details
University of Illinois at Chicago Chicago Illinois 60607 United States Details
University of Chicago Chicago Illinois 60637 United States Details
Franciscan Alliance Indianapolis Indiana 46237 United States Details
University of Kansas Medical Center Research Institute Inc Westwood Kansas 66205 United States Details
LSU Health Sciences Center Feist Weiller Cancer Center Shreveport Louisiana 71103 United States Details
University of Maryland Baltimore Maryland 21201 United States Details
Dana Farber Cancer Institute Boston Massachusetts 02215 United States Details
University of Michigan Health System Ann Arbor Michigan 48109 United States Details
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 United States Details
Mayo Clinic Rochester Minnesota 55905 United States Details
Washington University School of Medicine Saint Louis Missouri 63110 United States Details
University of Nebraska Medical Center Omaha Nebraska 68198 United States Details
John Theurer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601 United States Details
Roswell Park Cancer Institute Buffalo New York 14263 United States Details
Columbia University Medical Center New York New York 10032 United States Details
University of Rochester Rochester New York 14642 United States Details
NY Medical College Valhalla New York 10595 United States Details
UNC Linebreger Comprehensive Cancer Center Chapel Hill North Carolina 27599 United States Details
Duke Cancer Institute at Duke University Health System Durham North Carolina 27710 United States Details
Wake Forest University Baptist Health Winston-Salem North Carolina 27157 United States Details
University of Cincinnati Cincinnati Ohio 45267 United States Details
Oregon Health and Science University Knight Cancer Institute Portland Oregon 97239 United States Details
Geisinger Medical Center Danville Pennsylvania 17822 United States Details
Penn State Milton S Hershey Medical Center Hershey Pennsylvania 17033 United States Details
University of Pennsylvania Health System Philadelphia Pennsylvania 19104 United States Details
Avera Cancer Institute Sioux Falls South Dakota 57105 United States Details
Vanderbilt-Ingram Cancer Center Nashville Tennessee 37232 United States Details
MD Anderson Center, The University of Texas Houston Texas 77030 United States Details
Swedish Cancer Institute Seattle Washington 98104 United States Details
The Canbera Hospital Garran New South Wales 2605 Australia Details
Westmead Hospital Westmead New South Wales 2145 Australia Details
The Princess Alexandra Hospital Brisbane Queensland Australia Details
Royal Adelaide Hospital Adelaide South Australia 5000 Australia Details
The Queen Elizabeth Hospital Woodville South Australia 5011 Australia Details
Alfred Hospital Melbourne Victoria 3004 Australia Details
ZNA Stuivenberg Antwerpen BE 2060 Belgium Details
UCL St Luc Brussels BE 1200 Belgium Details
Leuven UZ Gasthuisberg Leuven BE 3000 Belgium Details
University of Alberta Hospital Edmonton Alberta T6G 2B7 Canada Details
Vancouver General Hospital Vancouver British Columbia V5Z 1M9 Canada Details
Princess Margaret Cancer Centre Princess Margaret Hospital Toronto Ontario M5G2M9 Canada Details
Klinička Bolinca Merkur Zagreb 10000 Croatia Details
Kliničko Bolnički Centar Zagreb Zagreb 10000 Croatia Details
Fakultni nemocnice Brno Brno 62500 Czechia Details
Fakultni nemocnice Hradec Kralove Hradec Králové 50005 Czechia Details
Fakultni nemocnice Olomouc Olomouc 77900 Czechia Details
CHU de Caen Caen 14000 France Details
Centre Hospitalier Universitaire Grenoble Hopital Michalon Grenoble 38043 France Details
Centre Hospitalier de Versailles Le Chesnay 78157 France Details
Hopital de la Conception Marseille 13385 France Details
Centre Hospitalier Universitaire Nantes Nantes 44035 France Details
Hôpital Saint Louis Paris 75010 France Details
Hopital Saint-Antoine Paris 75571 France Details
Hopital Haut Leveque Centre Francois Magendie Pessac 33604 France Details
Centre Henri-Becquerel Rouen 76038 France Details
Centre Hospitalier Universitaire Purpan Toulouse 31059 France Details
Charité Universitätsmedizin Berlin Berlin 12200 Germany Details
Charité Campus Virchow Klinikum Berlin 13353 Germany Details
Klinikum Braunschweig Braunschweig 38114 Germany Details
Universitatsklinikum Dresden Dresden 01307 Germany Details
Klinikum der Johann Wolfgang-Goethe-Universität Frankfurt 60590 Germany Details
Universitätsklinikum Halle Halle 06120 Germany Details
Medizinische Hochschule Hannover Hanover 30625 Germany Details
Uniklinik Heidelberg Medizinische Klinik und Poliklinik V Heidelberg 69120 Germany Details
Universitätsklinikum Jena Jena 07743 Germany Details
Universitätsklinikum Leipzig Leipzig 04103 Germany Details
University Mainz Mainz 55131 Germany Details
Universitätsklinikum Giessen und Marburg GmbH Marburg 35043 Germany Details
LMU München Klinikum Großhadern Munchen 81377 Germany Details
Medizinische Klinik A Hämatologie Hämostaseologie Internistische Onkologie und Pneumologie Münster 48149 Germany Details
The Chinese University of Hong Kong, Prince of Wales Hospital Hong Kong Hong Kong Details
The University of Hong Kong, Queen Mary Hospital Hong Kong Hong Kong Details
Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar Szent Gyorgyi Albert Klinikai Kozpont Szeged Csongrad 6725 Hungary Details
Debreceni Egyetem Klinikai Kozpont, Belgyogyaszati Intezet Debrecen Hajdu Bihar 4032 Hungary Details
Semmelweis Egyetem Altalanos Orvostudomanyi Kar I. Belgyogyaszati Klinika Budapest Pest 1083 Hungary Details
AOU Policlinico Consorziale di Bari Bari 70124 Italy Details
Università di Bologna Bologna 40138 Italy Details
Unità Operativa di Ematologia e Unità Operativa CTMO Cagliari Italy Details
Arcispedale S Anna Ferrara 44124 Italy Details
AOU Careggi Firenze 50134 Italy Details
IRCCS Azienda Ospedaliera Universitaria San Martino Genova 16132 Italy Details
Opsedale San Martino di Genova Genova 16132 Italy Details
Ospedale San Raffaele Milan 20132 Italy Details
Azienda Ospedaliera Universitaria Federico II Napoli 80131 Italy Details
Azienda Ospedaliero Universitaria San Luigi Gonzaga Orbassano 10043 Italy Details
L'UOC di Ematologia del Policlinico Tor Vergata Rome 00133 Italy Details
Policlinico Universitario Agostino Gemelli Rome 00168 Italy Details
Azienda Ospedaliero Universitaria Senese, Policlinico S. Maria alle Scotte Siena 53100 Italy Details
Ospedale di Circolo-a Fondazione Macchi Varese 21100 Italy Details
Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 463-707 Korea, Republic of Details
Kyungpook National University Hospital Daegu 700-721 Korea, Republic of Details
Seoul National University Hospital Seoul 110-744 Korea, Republic of Details
Samsung Medical Center Seoul 135-710 Korea, Republic of Details
The Catholic University of Korea Seoul St. Mary's Hospital Seoul 137-701 Korea, Republic of Details
Asan Medical Center Seoul 138-736 Korea, Republic of Details
VU Medisch Centrum Amsterdam 1081 HV Netherlands Details
Universitair Medisch Centrum Groningen Groningen 9713 GZ Netherlands Details
Erasmus Medical Center Rotterdam 3015 CE Netherlands Details
Uniwersytecki Szpital Kliniczny w Biatymstoku, Klinika Hematologii z Pododzialem Chorob Naczyn Bialystok 15276 Poland Details
Samodzielny Publiczny Szpital Kliniczny im. Andrzeja Mieleckiego Slaskiego Uniwersytetu Medycznego w Katowicach Oddzial Hematologii i Transplantacji Szpiku Katowice 40032 Poland Details
Samodzielny Publiczny Szpital Kliniczny Nr 1, Klinika Hematoonkologii i Transplantacji Szpiku Lublin 20081 Poland Details
Klinicki Centar Srbije Belgrade 11000 Serbia Details
Klinicki Centar Vojvodine Novi Sad 21000 Serbia Details
National University of Singapore Singapore 119228 Singapore Details
Singapore General Hospital Singapore 169608 Singapore Details
Hospital Son Espases Palma De Mallorca 07120 Spain Details
Hospital La Fe Valencia SP 46026 Spain Details
Hospital Clinic I Provincial de Barcelona Barcelona 08036 Spain Details
Hospital Universitari Germans Trias i Pujol Barcelona 08916 Spain Details
Hospital General Universitario Gregorio Marañon Madrid 28007 Spain Details
Complejo Hospitalario de Navarra Pamplona 31008 Spain Details
Hospital Clínico Universitario de Salamanca Salamanca 37007 Spain Details
Hospital Universitario Virgen del Rocio Sevilla 41013 Spain Details
China Medical University Hospital Taichung 404 Taiwan Details
National Cheng Kung University Hospital Tainan 704 Taiwan Details
National Taiwan University Hospital Taipei 100 Taiwan Details
Taipei Veterans General Hospital Taipei 112 Taiwan Details
Bristol Haematology and Oncology Centre Bristol England BS2 8ED United Kingdom Details
Saint James University Hospital Leeds England LS9 7TF United Kingdom Details
King's College Hospital London England SE5 9RS United Kingdom Details
Nottingham City Hospital NHS Trust Nottingham England NG51PB United Kingdom Details
Royal Marsden Hospital Sutton Sutton England SM2 5PT United Kingdom Details
Aberdeen Royal Infirmary Aberdeen Scotland AB25 2ZN United Kingdom Details
University Hospital of Wales Cardiff South Glamorgan CF14 4XW United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field