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| NCT ID | NCT02039726 |
| Title | (QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Daiichi Sankyo Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope National Medical Center | Duarte | California | 91010 | United States | Details | |
| University of Southern California, Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| UCLA Medical Center | Los Angeles | California | 90095 | United States | Details | |
| UC Davis Cancer Center | Sacramento | California | 95817 | United States | Details | |
| Stanford University Medical Center Stanford Comprehensive Cancer Center | Stanford | California | 94305 | United States | Details | |
| Yale University | New Haven | Connecticut | 06520 | United States | Details | |
| Emory Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| University of Illinois at Chicago | Chicago | Illinois | 60607 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| Franciscan Alliance | Indianapolis | Indiana | 46237 | United States | Details | |
| University of Kansas Medical Center Research Institute Inc | Westwood | Kansas | 66205 | United States | Details | |
| LSU Health Sciences Center Feist Weiller Cancer Center | Shreveport | Louisiana | 71103 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | United States | Details | |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| University of Rochester | Rochester | New York | 14642 | United States | Details | |
| NY Medical College | Valhalla | New York | 10595 | United States | Details | |
| UNC Linebreger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | United States | Details | |
| Duke Cancer Institute at Duke University Health System | Durham | North Carolina | 27710 | United States | Details | |
| Wake Forest University Baptist Health | Winston-Salem | North Carolina | 27157 | United States | Details | |
| University of Cincinnati | Cincinnati | Ohio | 45267 | United States | Details | |
| Oregon Health and Science University Knight Cancer Institute | Portland | Oregon | 97239 | United States | Details | |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | United States | Details | |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States | Details | |
| University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | United States | Details | |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | United States | Details | |
| MD Anderson Center, The University of Texas | Houston | Texas | 77030 | United States | Details | |
| Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| The Canbera Hospital | Garran | New South Wales | 2605 | Australia | Details | |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia | Details | |
| The Princess Alexandra Hospital | Brisbane | Queensland | Australia | Details | ||
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia | Details | |
| The Queen Elizabeth Hospital | Woodville | South Australia | 5011 | Australia | Details | |
| Alfred Hospital | Melbourne | Victoria | 3004 | Australia | Details | |
| ZNA Stuivenberg | Antwerpen | BE | 2060 | Belgium | Details | |
| UCL St Luc | Brussels | BE | 1200 | Belgium | Details | |
| Leuven UZ Gasthuisberg | Leuven | BE | 3000 | Belgium | Details | |
| University of Alberta Hospital | Edmonton | Alberta | T6G 2B7 | Canada | Details | |
| Vancouver General Hospital | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
| Princess Margaret Cancer Centre Princess Margaret Hospital | Toronto | Ontario | M5G2M9 | Canada | Details | |
| Klinička Bolinca Merkur | Zagreb | 10000 | Croatia | Details | ||
| Kliničko Bolnički Centar Zagreb | Zagreb | 10000 | Croatia | Details | ||
| Fakultni nemocnice Brno | Brno | 62500 | Czechia | Details | ||
| Fakultni nemocnice Hradec Kralove | Hradec Králové | 50005 | Czechia | Details | ||
| Fakultni nemocnice Olomouc | Olomouc | 77900 | Czechia | Details | ||
| CHU de Caen | Caen | 14000 | France | Details | ||
| Centre Hospitalier Universitaire Grenoble Hopital Michalon | Grenoble | 38043 | France | Details | ||
| Centre Hospitalier de Versailles | Le Chesnay | 78157 | France | Details | ||
| Hopital de la Conception | Marseille | 13385 | France | Details | ||
| Centre Hospitalier Universitaire Nantes | Nantes | 44035 | France | Details | ||
| Hôpital Saint Louis | Paris | 75010 | France | Details | ||
| Hopital Saint-Antoine | Paris | 75571 | France | Details | ||
| Hopital Haut Leveque Centre Francois Magendie | Pessac | 33604 | France | Details | ||
| Centre Henri-Becquerel | Rouen | 76038 | France | Details | ||
| Centre Hospitalier Universitaire Purpan | Toulouse | 31059 | France | Details | ||
| Charité Universitätsmedizin Berlin | Berlin | 12200 | Germany | Details | ||
| Charité Campus Virchow Klinikum | Berlin | 13353 | Germany | Details | ||
| Klinikum Braunschweig | Braunschweig | 38114 | Germany | Details | ||
| Universitatsklinikum Dresden | Dresden | 01307 | Germany | Details | ||
| Klinikum der Johann Wolfgang-Goethe-Universität | Frankfurt | 60590 | Germany | Details | ||
| Universitätsklinikum Halle | Halle | 06120 | Germany | Details | ||
| Medizinische Hochschule Hannover | Hanover | 30625 | Germany | Details | ||
| Uniklinik Heidelberg Medizinische Klinik und Poliklinik V | Heidelberg | 69120 | Germany | Details | ||
| Universitätsklinikum Jena | Jena | 07743 | Germany | Details | ||
| Universitätsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| University Mainz | Mainz | 55131 | Germany | Details | ||
| Universitätsklinikum Giessen und Marburg GmbH | Marburg | 35043 | Germany | Details | ||
| LMU München Klinikum Großhadern | Munchen | 81377 | Germany | Details | ||
| Medizinische Klinik A Hämatologie Hämostaseologie Internistische Onkologie und Pneumologie | Münster | 48149 | Germany | Details | ||
| The Chinese University of Hong Kong, Prince of Wales Hospital | Hong Kong | Hong Kong | Details | |||
| The University of Hong Kong, Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar Szent Gyorgyi Albert Klinikai Kozpont | Szeged | Csongrad | 6725 | Hungary | Details | |
| Debreceni Egyetem Klinikai Kozpont, Belgyogyaszati Intezet | Debrecen | Hajdu Bihar | 4032 | Hungary | Details | |
| Semmelweis Egyetem Altalanos Orvostudomanyi Kar I. Belgyogyaszati Klinika | Budapest | Pest | 1083 | Hungary | Details | |
| AOU Policlinico Consorziale di Bari | Bari | 70124 | Italy | Details | ||
| Università di Bologna | Bologna | 40138 | Italy | Details | ||
| Unità Operativa di Ematologia e Unità Operativa CTMO | Cagliari | Italy | Details | |||
| Arcispedale S Anna | Ferrara | 44124 | Italy | Details | ||
| AOU Careggi | Firenze | 50134 | Italy | Details | ||
| IRCCS Azienda Ospedaliera Universitaria San Martino | Genova | 16132 | Italy | Details | ||
| Opsedale San Martino di Genova | Genova | 16132 | Italy | Details | ||
| Ospedale San Raffaele | Milan | 20132 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Federico II | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliero Universitaria San Luigi Gonzaga | Orbassano | 10043 | Italy | Details | ||
| L'UOC di Ematologia del Policlinico Tor Vergata | Rome | 00133 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli | Rome | 00168 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Senese, Policlinico S. Maria alle Scotte | Siena | 53100 | Italy | Details | ||
| Ospedale di Circolo-a Fondazione Macchi | Varese | 21100 | Italy | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 463-707 | Korea, Republic of | Details | |
| Kyungpook National University Hospital | Daegu | 700-721 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 110-744 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 135-710 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul St. Mary's Hospital | Seoul | 137-701 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 138-736 | Korea, Republic of | Details | ||
| VU Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
| Universitair Medisch Centrum Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Erasmus Medical Center | Rotterdam | 3015 CE | Netherlands | Details | ||
| Uniwersytecki Szpital Kliniczny w Biatymstoku, Klinika Hematologii z Pododzialem Chorob Naczyn | Bialystok | 15276 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny im. Andrzeja Mieleckiego Slaskiego Uniwersytetu Medycznego w Katowicach Oddzial Hematologii i Transplantacji Szpiku | Katowice | 40032 | Poland | Details | ||
| Samodzielny Publiczny Szpital Kliniczny Nr 1, Klinika Hematoonkologii i Transplantacji Szpiku | Lublin | 20081 | Poland | Details | ||
| Klinicki Centar Srbije | Belgrade | 11000 | Serbia | Details | ||
| Klinicki Centar Vojvodine | Novi Sad | 21000 | Serbia | Details | ||
| National University of Singapore | Singapore | 119228 | Singapore | Details | ||
| Singapore General Hospital | Singapore | 169608 | Singapore | Details | ||
| Hospital Son Espases | Palma | De Mallorca | 07120 | Spain | Details | |
| Hospital La Fe | Valencia | SP | 46026 | Spain | Details | |
| Hospital Clinic I Provincial de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitari Germans Trias i Pujol | Barcelona | 08916 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon | Madrid | 28007 | Spain | Details | ||
| Complejo Hospitalario de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hospital Clínico Universitario de Salamanca | Salamanca | 37007 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| China Medical University Hospital | Taichung | 404 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 112 | Taiwan | Details | ||
| Bristol Haematology and Oncology Centre | Bristol | England | BS2 8ED | United Kingdom | Details | |
| Saint James University Hospital | Leeds | England | LS9 7TF | United Kingdom | Details | |
| King's College Hospital | London | England | SE5 9RS | United Kingdom | Details | |
| Nottingham City Hospital NHS Trust | Nottingham | England | NG51PB | United Kingdom | Details | |
| Royal Marsden Hospital Sutton | Sutton | England | SM2 5PT | United Kingdom | Details | |
| Aberdeen Royal Infirmary | Aberdeen | Scotland | AB25 2ZN | United Kingdom | Details | |
| University Hospital of Wales | Cardiff | South Glamorgan | CF14 4XW | United Kingdom | Details |