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NCT ID NCT02521493
Title Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Children's Oncology Group
Indications

acute myeloid leukemia

Therapies

Etoposide

Thioguanine

Cytarabine

Asparaginase Erwinia chrysanthemi

mitoxantrone hydrochloride

Daunorubicin

Asparaginase

Age Groups: child
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Children's Hospital of Alabama Birmingham Alabama 35233 United States Details
Providence Alaska Medical Center Anchorage Alaska 99508 United States Details
Banner Children's at Desert Mesa Arizona 85202 United States Details
Phoenix Childrens Hospital Phoenix Arizona 85016 United States Details
Arkansas Children's Hospital Little Rock Arkansas 72202-3591 United States Details
Kaiser Permanente Downey Medical Center Downey California 90242 United States Details
Loma Linda University Medical Center Loma Linda California 92354 United States Details
Miller Children's and Women's Hospital Long Beach Long Beach California 90806 United States Details
Children's Hospital Los Angeles Los Angeles California 90027 United States Details
Cedars Sinai Medical Center Los Angeles California 90048 United States Details
Valley Children's Hospital Madera California 93636 United States Details
UCSF Benioff Children's Hospital Oakland Oakland California 94609 United States Details
Kaiser Permanente-Oakland Oakland California 94611 United States Details
Children's Hospital of Orange County Orange California 92868 United States Details
Lucile Packard Children's Hospital Stanford University Palo Alto California 94304 United States Details
Sutter Medical Center Sacramento Sacramento California 95816 United States Details
University of California Davis Comprehensive Cancer Center Sacramento California 95817 United States Details
Rady Children's Hospital - San Diego San Diego California 92123 United States Details
Naval Medical Center -San Diego San Diego California 92134 United States Details
UCSF Medical Center-Mission Bay San Francisco California 94158 United States Details
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Torrance California 90502 United States Details
Children's Hospital Colorado Aurora Colorado 80045 United States Details
Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center Denver Colorado 80218 United States Details
Connecticut Children's Medical Center Hartford Connecticut 06106 United States Details
Yale University New Haven Connecticut 06520 United States Details
Alfred I duPont Hospital for Children Wilmington Delaware 19803 United States Details
MedStar Georgetown University Hospital Washington District of Columbia 20007 United States Details
Children's National Medical Center Washington District of Columbia 20010 United States Details
Broward Health Medical Center Fort Lauderdale Florida 33316 United States Details
Golisano Children's Hospital of Southwest Florida Fort Myers Florida 33908 United States Details
University of Florida Health Science Center - Gainesville Gainesville Florida 32610 United States Details
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood Florida 33021 United States Details
Nemours Children's Clinic-Jacksonville Jacksonville Florida 32207 United States Details
Palms West Radiation Therapy Loxahatchee Groves Florida 33470 United States Details
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami Florida 33136 United States Details
Nicklaus Children's Hospital Miami Florida 33155 United States Details
AdventHealth Orlando Orlando Florida 32803 United States Details
Arnold Palmer Hospital for Children Orlando Florida 32806 United States Details
Nemours Children's Hospital Orlando Florida 32827 United States Details
Nemours Children's Clinic - Pensacola Pensacola Florida 32504 United States Details
Sacred Heart Hospital Pensacola Florida 32504 United States Details
Johns Hopkins All Children's Hospital Saint Petersburg Florida 33701 United States Details
Saint Joseph's Hospital/Children's Hospital-Tampa Tampa Florida 33607 United States Details
Saint Mary's Hospital West Palm Beach Florida 33407 United States Details
Children's Healthcare of Atlanta - Egleston Atlanta Georgia 30322 United States Details
Memorial Health University Medical Center Savannah Georgia 31404 United States Details
Kapiolani Medical Center for Women and Children Honolulu Hawaii 96826 United States Details
Saint Luke's Cancer Institute - Boise Boise Idaho 83712 United States Details
Lurie Children's Hospital-Chicago Chicago Illinois 60611 United States Details
University of Illinois Chicago Illinois 60612 United States Details
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637 United States Details
Advocate Children's Hospital-Oak Lawn Oak Lawn Illinois 60453 United States Details
Advocate Children's Hospital-Park Ridge Park Ridge Illinois 60068 United States Details
Saint Jude Midwest Affiliate Peoria Illinois 61637 United States Details
Southern Illinois University School of Medicine Springfield Illinois 62702 United States Details
Riley Hospital for Children Indianapolis Indiana 46202 United States Details
Saint Vincent Hospital and Health Care Center Indianapolis Indiana 46260 United States Details
Blank Children's Hospital Des Moines Iowa 50309 United States Details
University of Iowa/Holden Comprehensive Cancer Center Iowa City Iowa 52242 United States Details
University of Kentucky/Markey Cancer Center Lexington Kentucky 40536 United States Details
Norton Children's Hospital Louisville Kentucky 40202 United States Details
Children's Hospital New Orleans New Orleans Louisiana 70118 United States Details
Ochsner Medical Center Jefferson New Orleans Louisiana 70121 United States Details
Eastern Maine Medical Center Bangor Maine 04401 United States Details
Sinai Hospital of Baltimore Baltimore Maryland 21215 United States Details
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287 United States Details
Walter Reed National Military Medical Center Bethesda Maryland 20889-5600 United States Details
Tufts Children's Hospital Boston Massachusetts 02111 United States Details
Dana-Farber Cancer Institute Boston Massachusetts 02215 United States Details
Baystate Medical Center Springfield Massachusetts 01199 United States Details
UMass Memorial Medical Center - University Campus Worcester Massachusetts 01655 United States Details
C S Mott Children's Hospital Ann Arbor Michigan 48109 United States Details
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201 United States Details
Ascension Saint John Hospital Detroit Michigan 48236 United States Details
Michigan State University Clinical Center East Lansing Michigan 48824-7016 United States Details
Hurley Medical Center Flint Michigan 48503 United States Details
Helen DeVos Children's Hospital at Spectrum Health Grand Rapids Michigan 49503 United States Details
Bronson Methodist Hospital Kalamazoo Michigan 49007 United States Details
Beaumont Children's Hospital-Royal Oak Royal Oak Michigan 48073 United States Details
Children's Hospitals and Clinics of Minnesota - Minneapolis Minneapolis Minnesota 55404 United States Details
University of Minnesota/Masonic Cancer Center Minneapolis Minnesota 55455 United States Details
Mayo Clinic in Rochester Rochester Minnesota 55905 United States Details
University of Mississippi Medical Center Jackson Mississippi 39216 United States Details
Columbia Regional Columbia Missouri 65201 United States Details
Children's Mercy Hospitals and Clinics Kansas City Missouri 64108 United States Details
Washington University School of Medicine Saint Louis Missouri 63110 United States Details
Mercy Hospital Saint Louis Saint Louis Missouri 63141 United States Details
University Medical Center of Southern Nevada Las Vegas Nevada 89102 United States Details
Sunrise Hospital and Medical Center Las Vegas Nevada 89109 United States Details
Alliance for Childhood Diseases/Cure 4 the Kids Foundation Las Vegas Nevada 89135 United States Details
Summerlin Hospital Medical Center Las Vegas Nevada 89144 United States Details
Renown Regional Medical Center Reno Nevada 89502 United States Details
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 United States Details
Hackensack University Medical Center Hackensack New Jersey 07601 United States Details
Morristown Medical Center Morristown New Jersey 07960 United States Details
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital New Brunswick New Jersey 08903 United States Details
Saint Joseph's Regional Medical Center Paterson New Jersey 07503 United States Details
University of New Mexico Cancer Center Albuquerque New Mexico 87102 United States Details
Presbyterian Hospital Albuquerque New Mexico 87106 United States Details
Albany Medical Center Albany New York 12208 United States Details
Montefiore Medical Center - Moses Campus Bronx New York 10467 United States Details
Roswell Park Cancer Institute Buffalo New York 14263 United States Details
NYU Winthrop Hospital Mineola New York 11501 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York New York 10016 United States Details
Mount Sinai Hospital New York New York 10029 United States Details
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032 United States Details
NYP/Weill Cornell Medical Center New York New York 10065 United States Details
University of Rochester Rochester New York 14642 United States Details
Stony Brook University Medical Center Stony Brook New York 11794 United States Details
State University of New York Upstate Medical University Syracuse New York 13210 United States Details
New York Medical College Valhalla New York 10595 United States Details
Mission Hospital Asheville North Carolina 28801 United States Details
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina 27599 United States Details
Carolinas Medical Center/Levine Cancer Institute Charlotte North Carolina 28203 United States Details
Novant Health Presbyterian Medical Center Charlotte North Carolina 28204 United States Details
Duke University Medical Center Durham North Carolina 27710 United States Details
East Carolina University Greenville North Carolina 27834 United States Details
Wake Forest University Health Sciences Winston-Salem North Carolina 27157 United States Details
Sanford Broadway Medical Center Fargo North Dakota 58122 United States Details
Children's Hospital Medical Center of Akron Akron Ohio 44308 United States Details
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 United States Details
Rainbow Babies and Childrens Hospital Cleveland Ohio 44106 United States Details
Cleveland Clinic Foundation Cleveland Ohio 44195 United States Details
Nationwide Children's Hospital Columbus Ohio 43205 United States Details
Dayton Children's Hospital Dayton Ohio 45404 United States Details
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital Toledo Ohio 43606 United States Details
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 United States Details
Legacy Emanuel Children's Hospital Portland Oregon 97227 United States Details
Oregon Health and Science University Portland Oregon 97239 United States Details
Geisinger Medical Center Danville Pennsylvania 17822 United States Details
Penn State Children's Hospital Hershey Pennsylvania 17033 United States Details
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 United States Details
Saint Christopher's Hospital for Children Philadelphia Pennsylvania 19134 United States Details
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 United States Details
Rhode Island Hospital Providence Rhode Island 02903 United States Details
Medical University of South Carolina Charleston South Carolina 29425 United States Details
BI-LO Charities Children's Cancer Center Greenville South Carolina 29605 United States Details
Sanford USD Medical Center - Sioux Falls Sioux Falls South Dakota 57117-5134 United States Details
T C Thompson Children's Hospital Chattanooga Tennessee 37403 United States Details
East Tennessee Childrens Hospital Knoxville Tennessee 37916 United States Details
Saint Jude Children's Research Hospital Memphis Tennessee 38105 United States Details
The Children's Hospital at TriStar Centennial Nashville Tennessee 37203 United States Details
Vanderbilt University/Ingram Cancer Center Nashville Tennessee 37232 United States Details
Texas Tech University Health Sciences Center-Amarillo Amarillo Texas 79106 United States Details
Dell Children's Medical Center of Central Texas Austin Texas 78723 United States Details
Driscoll Children's Hospital Corpus Christi Texas 78411 United States Details
Medical City Dallas Hospital Dallas Texas 75230 United States Details
UT Southwestern/Simmons Cancer Center-Dallas Dallas Texas 75390 United States Details
El Paso Children's Hospital El Paso Texas 79905 United States Details
Cook Children's Medical Center Fort Worth Texas 76104 United States Details
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center Houston Texas 77030 United States Details
Covenant Children's Hospital Lubbock Texas 79410 United States Details
UMC Cancer Center / UMC Health System Lubbock Texas 79415 United States Details
Children's Hospital of San Antonio San Antonio Texas 78207 United States Details
Methodist Children's Hospital of South Texas San Antonio Texas 78229 United States Details
University of Texas Health Science Center at San Antonio San Antonio Texas 78229 United States Details
Primary Children's Hospital Salt Lake City Utah 84113 United States Details
University of Vermont and State Agricultural College Burlington Vermont 05405 United States Details
Inova Fairfax Hospital Falls Church Virginia 22042 United States Details
Children's Hospital of The King's Daughters Norfolk Virginia 23507 United States Details
Virginia Commonwealth University/Massey Cancer Center Richmond Virginia 23298 United States Details
Seattle Children's Hospital Seattle Washington 98105 United States Details
Providence Sacred Heart Medical Center and Children's Hospital Spokane Washington 99204 United States Details
Mary Bridge Children's Hospital and Health Center Tacoma Washington 98405 United States Details
Madigan Army Medical Center Tacoma Washington 98431 United States Details
West Virginia University Charleston Division Charleston West Virginia 25304 United States Details
Saint Vincent Hospital Cancer Center Green Bay Green Bay Wisconsin 54301 United States Details
University of Wisconsin Carbone Cancer Center Madison Wisconsin 53792 United States Details
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226 United States Details
John Hunter Children's Hospital Hunter Regional Mail Centre New South Wales 2310 Australia Details
Sydney Children's Hospital Randwick New South Wales 2031 Australia Details
The Children's Hospital at Westmead Westmead New South Wales 2145 Australia Details
Royal Children's Hospital Parkville Victoria 3052 Australia Details
Princess Margaret Hospital for Children Perth Western Australia 6008 Australia Details
Perth Children's Hospital Perth Western Australia 6009 Australia Details
British Columbia Children's Hospital Vancouver British Columbia V6H 3V4 Canada Details
CancerCare Manitoba Winnipeg Manitoba R3E 0V9 Canada Details
IWK Health Centre Halifax Nova Scotia B3K 6R8 Canada Details
McMaster Children's Hospital at Hamilton Health Sciences Hamilton Ontario L8N 3Z5 Canada Details
Kingston Health Sciences Centre Kingston Ontario K7L 2V7 Canada Details
Children's Hospital London Ontario N6A 5W9 Canada Details
Children's Hospital of Eastern Ontario Ottawa Ontario K1H 8L1 Canada Details
Hospital for Sick Children Toronto Ontario M5G 1X8 Canada Details
The Montreal Children's Hospital of the MUHC Montreal Quebec H3H 1P3 Canada Details
Centre Hospitalier Universitaire Sainte-Justine Montreal Quebec H3T 1C5 Canada Details
Centre Hospitalier Universitaire de Quebec Quebec G1V 4G2 Canada Details
Starship Children's Hospital Grafton Auckland 1145 New Zealand Details
Christchurch Hospital Christchurch 8011 New Zealand Details
San Jorge Children's Hospital San Juan 00912 Puerto Rico Details
University Pediatric Hospital San Juan 00926 Puerto Rico Details
King Faisal Specialist Hospital and Research Centre Riyadh 11211 Saudi Arabia Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field