Clinical Trial Detail

NCT ID NCT02563002
Title Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements yes
Sponsors Merck Sharp & Dohme Corp.
Indications

colorectal cancer

Therapies

Fluorouracil + Leucovorin + Oxaliplatin

Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin

Fluorouracil + Irinotecan + Leucovorin

Cetuximab + Fluorouracil + Irinotecan + Leucovorin

Bevacizumab + Fluorouracil + Irinotecan + Leucovorin

Cetuximab + Fluorouracil + Leucovorin + Oxaliplatin

Pembrolizumab

Age Groups: adult senior

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