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NCT ID NCT02668653
Title Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML) (QuANTUM-First)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Daiichi Sankyo Inc.

acute myeloid leukemia


Cytarabine + Daunorubicin + Idarubicin

Cytarabine + Daunorubicin + Idarubicin + Quizartinib

Age Groups: senior | adult
Covered Countries USA | CAN

Facility Status City State Zip Country Details
University of Florida (UF) Health Shands Hospital Gainesville Florida 90095-7170 United States Details
The University of Chicago Medical Center Chicago Illinois 60637 United States Details
Franciscan St. Francis Health Indianapolis Indianapolis Indiana 46237 United States Details
University of Kentucky Chandler Medical Center Lexington Kentucky 40536-0293 United States Details
John Theurer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601 United States Details
NY Medical College - Hudson Valley Hematology Oncology Associates Valhalla New York 10595 United States Details
Duke Clinical Research Institute Durham North Carolina 27710 United States Details
University Hospitals Seidman Cancer Center Cleveland Ohio 44106 United States Details
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 United States Details
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107-4307 United States Details
West Virginia University Hospitals, Inc. Morgantown West Virginia 26506 United States Details
Sanatorio Britanico Rosario Santa Fe S2000CVB Argentina Details
Sanatorio Allende Córdoba X5000JHQ Argentina Details
Calvary Mater Newcastle Waratah New South Wales 2298 Australia Details
Townsville Hospital (TTH) Douglas Queensland 4814 Australia Details
Princess Alexandra Hospital Woolloongabba Queensland 4102 Australia Details
Fiona Stanley Hospital Murdoch Western Australia 6150 Australia Details
AZ Sint-Jan Brugge-Oostende AV Brugge 8000 Belgium Details
Universitair Ziekenhuis Gent Gent 9000 Belgium Details
UCL Mont-Godinne Yvoir 5530 Belgium Details
Hospital Amaral Carvalho Brasília 70750-521 Brazil Details
Hospital do CEPON Brasília 70750-521 Brazil Details
Instituto do Cancer do Estado de São Paulo Brasília 70750-521 Brazil Details
Santa Casa de Misericórdia de Porto Alegre Brasília 70750-521 Brazil Details
Hospital da Cidade de Passo Fundo Passo Fundo 99010-260 Brazil Details
Hospital de Clínicas de Porto Alegre Porto Alegre 90035-903 Brazil Details
University Multiprofile Hospital for Active Treatment "Dr. G. Stranski" EAD Pleven 5800 Bulgaria Details
University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD Sofia 1000 Bulgaria Details
Tom Baker Cancer Centre Calgary Alberta T2N 4N2 Canada Details
University of Alberta Hospital Edmonton Alberta T6G-3G3 Canada Details
Vancouver General Hospital (VGH) Vancouver British Columbia V5Z 1M9 Canada Details
Princess Margaret Cancer Centre Toronto Ontario M5G 1X5 Canada Details
Peking University First Hospital Beijing 100034 China Details
The General Hospital of People's Liberation Army (301 Hospital) Beijing 100853 China Details
Fujian Medical University Union Hospital Fuzhou 350001 China Details
Guangdong General Hospital Guangzhou 510030 China Details
Lanzhou University Second Hospital Lanzhou 730030 China Details
Ruijin Hospital Affiliated to The Shanghai Jiao Tong University Medical School Shanghai 200025 China Details
West China Hospital, Sichuan University Taiyuan 30001 China Details
Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences Tianjin 300020 China Details
The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325015 China Details
Tang Du Hospital, Fourth Military Medical University Xi'an 710038 China Details
Henan Cancer Hospital Zhengzhou 450008 China Details
Klinička Bolnica Dubrava Zagreb 10000 Croatia Details
Klinička Bolnica Merkur Zagreb 10000 Croatia Details
Klinički Bolnički Centar Zagreb Zagreb 10000 Croatia Details
Fakultní Nemocnice Hradec Králové Hradec Kralove 500 05 Czechia Details
Fakultní Nemocnice Olomouc Olomouc 775 20 Czechia Details
Fakultní Nemocnice Ostrava Ostrava 708 52 Czechia Details
Fakultni Nemocnice Plzen Plzen 304 60 Czechia Details
Vseobecna Fakultni Nemocnice, Ustav hematologie a krevni transfuze (UHKT) Praha 2 128 20 Czechia Details
Hospital A. Michallon Grenoble 38043 France Details
Centre Hospitalier de Versailles - Hôpital André Mignot Le Chesnay 78150 France Details
Centre Hospitalier Régional Universitaire de Lille (CHRU) - Hôpital Claude Huriez Lille 59037 France Details
Centre Léon Bérard Lyon 69373 France Details
L'Institut Paoli - Calmettes Marguerittes 13009 France Details
Hôpital de la Conception Marseille 13385 France Details
CHRU Montpellier - Saint Eloi Montpellier 34295 France Details
Hôpital Saint-Antoine Paris 75012 France Details
Hôpital Saint-Louis Paris 75475 France Details
Hôpital Haut-Lévêque Pessac 33604 France Details
Centre Hospitalier Lyon-Sud Pierre Benite 69495 France Details
Centre Henri Becquerel - Centre de Lutte Contre le Cancer Rouen 76038 France Details
Centre Hospitalier Universitaire de Toulouse - Hôpital Purpan Toulouse 31059 France Details
HELIOS Klinikum Bad Saarow Bad Saarow 15526 Germany Details
Charité - Universitätsmedizin Berlin Berlin 10117 Germany Details
Städtisches Klinikum Braunschweig gGmbH Braunschweig 38114 Germany Details
Marien Hospital Düsseldorf GmbH Düsseldorf 40479 Germany Details
Universitätsklinikum Essen Essen 45122 Germany Details
Universitätsklinikum Frankfurt Frankfurt am Main 60590 Germany Details
Universitätsklinikum Halle (Saale) Halle 6120 Germany Details
Evangelisches Krankenhaus Hamm gGmbH Hamm 59063 Germany Details
Medizinische Hochschule Hannover (MHH) Hannöver 30625 Germany Details
Universitätsklinikum Münster Heidelberg 69115 Germany Details
Universitätsklinikum Tübingen Heidelberg 69115 Germany Details
Universitätsklinikum Heidelberg Heidelberg 69120 Germany Details
Universitätsklinikum Leipzig Leipzig 4103 Germany Details
Stauferklinikum Schwäbisch Gmünd Mutlangen 73557 Germany Details
HELIOS Klinikum Wuppertal Wuppertal 42283 Germany Details
Prince of Wales Hospital Shatin Hong Kong Details
Markusovszky Egyetemi Oktatókórház Budapest 1051 Hungary Details
Szegedi Tudományegyetem Budapest 1051 Hungary Details
Semmelweis Egyetem Budapest 1083 Hungary Details
Debreceni Egyetem Klinikai Központ Debrecen 4032 Hungary Details
Pecsi Tudomanyegyetem Klinikai Központ Pécs 7624 Hungary Details
Markusovszky Egyetemi Oktatókórház Szombathely 9700 Hungary Details
Assaf Harofeh Medical Center Be'er Ya'aqov Tsifrin 70300 Israel Details
Bnai Zion Medical Center Haifa 31048 Israel Details
Rambam Medical Center Haifa 31096 Israel Details
Hadassah University Medical Center Jerusalem 91120 Israel Details
Rabin Medical Center - Beilinson Hospital Petaẖ Tiqwa 49100 Israel Details
The Chaim Sheba Medical Center Ramat-Gan 52621 Israel Details
Tel Aviv Sourasky Medical Center Tel Aviv 64239 Israel Details
Azienda Ospedaliera Nazionale SS.Antonio e Biagio e Cesare Arrigo Alessandria 15121 Italy Details
Azienda Sanitaria Locale 13 - Ospedale "C. e G. Mazzoni"- Ascoli Piceno Ascoli Piceno 63100 Italy Details
Azienda Ospedaliero - Universitaria Consorziale Policlinico di Bari Bari 70124 Italy Details
Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi Bologna 40138 Italy Details
IRCCS AOU San Martino - IST Genova 16132 Italy Details
ASST Grande Ospedale Metropolitano Niguarda Milano 20162 Italy Details
A.O.R.N. "A. Cardarelli" Napoli 80131 Italy Details
Azienda Ospedaliero Universitaria Maggiore della Carità di Novara Novara 28100 Italy Details
Azienda Ospedaliero - Universitaria San Luigi Gonzaga Orbassano 10043 Italy Details
Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello Palermo 90146 Italy Details
Ospedale S. Maria delle Croci - Ravenna Ravenna 48121 Italy Details
Fondazione Policlinico Universitario Agostino Gemelli Roma 133 Italy Details
Ospedale S. Eugenio Roma 133 Italy Details
Policlinico Tor Vergata Roma 133 Italy Details
IRCCS Ospedale San Raffaele Roma 20132 Italy Details
Azienda Ospedaliero-Universitaria Careggi Roma 50134 Italy Details
Azienda Ospedaliero Universitaria Pisana - Ospedale Santa Chiara Roma 56126 Italy Details
Azienda Ospedaliera Universitaria "Federico II" Roma 80131 Italy Details
Istituto Clinico Humanitas Rozzano 20089 Italy Details
Azienda Ospedaliera Universitaria OO.RR. San Giovanni di Dio Ruggi d'Aragona Salerno 84131 Italy Details
Azienda Ospedaliera Universitaria Senese Siena 53100 Italy Details
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino - Ospedale Molinette Torino 10126 Italy Details
Azienda Ospedaliera Ordine Mauriziano di Torino Torino 10128 Italy Details
ASST dei Sette Laghi - Ospedale di Circolo e Fondazione Macchi Varese Varese 21100 Italy Details
National Hospital Organization Nagoya Medical Center Nagoya Aichi 460-0001 Japan Details
Nagoya University Hospital Nagoya Aichi 466-8560 Japan Details
Toyohashi Municipal Hospital Toyohashi Aichi 441-8570 Japan Details
Ehime Prefectural Central Hospital Matsuyama Ehime 790-0024 Japan Details
University of Fukui Hospital Yoshida Fukui 910-1193 Japan Details
Kyushu University Hospital Higashi Fukuoka 812-8582 Japan Details
Gunmaken Saiseikai Maebashi Hospital Maebashi Gunma 371-0821 Japan Details
Gunma University Hospital Maebashi Gunma 371-8511 Japan Details
Chugoku Central Hospital Fukuyama Hiroshima 720-0001 Japan Details
Sapporo Hokuyu Hospital Sapporo Hokkaido 003-0006 Japan Details
Yokohama City University Hospital Yokohama Kanagawa 236-0004 Japan Details
National Hospital Organization Sendai Medical Center Sendai Miagi 983-8520 Japan Details
Tenri Hospital Tenri Nara 632-8552 Japan Details
Hamamatsu University Hospital Hamamatsu Shizuoka 431-3192 Japan Details
Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital Bunkyō-Ku Tokyo 113-8677 Japan Details
The Jikei University Hospital Minato-Ku Tokyo 105-0003 Japan Details
Akita University Hospital Akita 010-8543 Japan Details
Aomori Prefectural Central Hospital Aomori 030-8553 Japan Details
Chiba Aoba Municipal Hospital Chiba 260-0852 Japan Details
Kameda Medical Center - Kameda General Hospital Chiba 296-0041 Japan Details
National Hospital Organization Kyushu Cancer Center Fukuoka 811-1395 Japan Details
Gifu Municipal Hospital Gifu 500-8513 Japan Details
National Hospital Organization Kagoshima Medical Center Kagoshima 892-0853 Japan Details
Kobe City Medical Center General Hospital Kobe 650-0047 Japan Details
National Hospital Organization Kumamoto Medical Center Kumamoto 860-0008 Japan Details
Nagasaki University Hospital Nagasaki 852-8501 Japan Details
Osaka City General Hospital Osaka 534-0021 Japan Details
Osaka Red Cross Hospital Osaka 543-8555 Japan Details
NTT Medical Center Tokyo Tokyo 141-8625 Japan Details
Inje University Haeundae Paik Hospital Busan 48108 Korea, Republic of Details
Pusan National University Hospital Busan 49241 Korea, Republic of Details
Kyungpook National University Hospital Daegu 41944 Korea, Republic of Details
Yeungnam University Medical Center Daegu 42415 Korea, Republic of Details
Daegu Catholic University Medical Center Daegu 42472 Korea, Republic of Details
Chonnam National University Hwasun Hospital Hwasun 58128 Korea, Republic of Details
Gachon University Gil Hospital Incheon 21565 Korea, Republic of Details
Seoul National University Bundang Hospital Seongnam-si 13620 Korea, Republic of Details
Seoul National University Hospital Seoul 3080 Korea, Republic of Details
Severance Hospital Seoul 3722 Korea, Republic of Details
SoonChunHyang University Seoul Hospital Seoul 4401 Korea, Republic of Details
Konkuk University Medical Center Seoul 5030 Korea, Republic of Details
Asan Medical Center Seoul 5505 Korea, Republic of Details
Samsung Medical Center Seoul 6351 Korea, Republic of Details
The Catholic University of Korea, Seoul St. Mary's Hospital Seoul 6591 Korea, Republic of Details
Korea University Guro Hospital Seoul 8308 Korea, Republic of Details
Ajou University Hospital Sŏwŏn 16499 Korea, Republic of Details
Ulsan University Hospital (UUH) Ulsan 44033 Korea, Republic of Details
Szpital Uniwersytecki w Krakowie Kraków 31-501 Poland Details
Wojewódzki Szpital Specjalistyczny im. Janusza Korczaka Słupsk 76-200 Poland Details
Instytut Hematologii i Transfuzjologi Warszawa 00-957 Poland Details
Samodzielny Publiczny Szpital Kliniczny Nr. 1 we Wrocławiu Warszawa 50367 Poland Details
Centro Hospitalar e Universitário de Coimbra, EPE - Hospitais da Universidade de Coimbra Coimbra 3000-075 Portugal Details
Centro Hospitalar Lisboa Central, EPE - Hospital Santo António dos Capuchos Lisboa 1169050 Portugal Details
Centro Hospitalar do Porto, EPE - Hospital Geral de Santo António Porto 4099-001 Portugal Details
Instituto Português Oncologia do Porto Francisco Gentil, EPE Porto 4200-072 Portugal Details
Centro Hospitalar de São João, EPE - Hospital de São João Porto 4200-319 Portugal Details
Institutul Regional de Oncologie Iași Bucuresti 20125 Romania Details
Spitalul Clinic Colentina Bucuresti 20125 Romania Details
Spitalul Clinic Coltea Bucuresti 20125 Romania Details
Spitalul Universitar de Urgenta Bucuresti Bucuresti 20125 Romania Details
Institutul Clinic Fundeni Bucuresti 22328 Romania Details
Institutul Oncologic "Prof. Dr. Ion Chiricuţă" Cluj Napoca Cluj-Napoca 400124 Romania Details
Spitalul Clinic Municipal Filantropia Craiova Craiova 200143 Romania Details
Spitalul Clinic Judetean de Urgenta Târgu-Mureş (4005) Târgu-Mureş 540042 Romania Details
Spitalul Clinic Judetean de Urgenta Târgu-Mureş (4008) Târgu-Mureş 540136 Romania Details
Nizhny Novgorod Regional Clinical Hospital Nizhny Novgorod 603126 Russian Federation Details
Penza Regional Oncology Dispensary Penza 440071 Russian Federation Details
Republican Hospital n.a.V.A. Baranov Petrozavodsk 185019 Russian Federation Details
Ryazan Regional Clinical Hospital Ryazan' 390039 Russian Federation Details
Almazov Federal North-West Medical Research Centre Saint Petersburg 197341 Russian Federation Details
Saratov State Medical University named after V.I. Razumovsky Saratov 410012 Russian Federation Details
Russian Research Institute of Hematology and Blood Transfusion St. Petersburg 191024 Russian Federation Details
Leningrad Regional Clinic and Hospital St. Petersburg 194291 Russian Federation Details
Tula Regional Clinical Hospital Tula 300053 Russian Federation Details
Klinički Centar Srbije Belgrade 11000 Serbia Details
Klinički Centar Niš Nis 18000 Serbia Details
Klinički Centar Vojvodine Novi Sad 21101 Serbia Details
National University Hospital (S) Pte Ltd Singapore 119074 Singapore Details
Singapore General Hospital Singapore 138543 Singapore Details
Hospital Universitari Son Espases Palma Mallorca 7014 Spain Details
Complejo Hospitalario Universitario de Albacete - Hospital General Universitario Albacete 2006 Spain Details
Hospital General Universitario de Alicante Alicante 3010 Spain Details
Catalan Institute of Oncology (ICO) Badalona 8916 Spain Details
Hospital del Mar Barcelona 8003 Spain Details
Hospital Universitario Vall d'Hebron Barcelona 8035 Spain Details
Hospital Clinic i Provincial Barcelona 8036 Spain Details
Hospital Duran i Reynals Barcelona 8907 Spain Details
Hospital de Basurto Bilbao 48013 Spain Details
Hospital San Pedro de Alcántara Cáceres 10002 Spain Details
Hospital Universitario Reina Sofía Córdoba 14004 Spain Details
Hospital Universitari de Girona Doctor Josep Trueta Girona 17007 Spain Details
Complejo Hospitalario Universitario Granada Granada 18014 Spain Details
Complexo Hospitalario Universitario A Coruña La Coruña 15006 Spain Details
Hospital Dr. Negrín Las Palmas De Gran Canaria 35010 Spain Details
Hospital General Universitario Gregorio Marañón Madrid 28007 Spain Details
Hospital Universitario Ramón y Cajal Madrid 28034 Spain Details
Hospital Clínico San Carlos Madrid 28040 Spain Details
Hospital Universitario 12 de Octubre Madrid 28041 Spain Details
Hospital Quirón Madrid Madrid 28223 Spain Details
Hospital Universitario Puerta de Hierro - Majadahonda Majadahonda 28222 Spain Details
Hospital Regional Universitario de Málaga - Hospital General Málaga 29010 Spain Details
Hospital Universitario Central de Asturias Oviedo 33011 Spain Details
Complejo Hospitalario de Navarra Pamplona 31008 Spain Details
Fundación Jiménez Díaz Pamplona 31008 Spain Details
Hospital Clínico Universitario "Lozano Blesa" Pamplona 31008 Spain Details
Hospital General Universitario Morales Meseguer Pamplona 31008 Spain Details
Hospital Universitario Miguel Servet Pamplona 31008 Spain Details
Hospital Álvaro Cunqueiro Pamplona 31008 Spain Details
Hosp Universitario Salamanca Salamanca 37007 Spain Details
Hospital Universitario Marqués de Valdecilla Santander 39008 Spain Details
Complexo Hospitalario Universitario de Santiago (CHUS) - Hospital Clínico Universitario Santiago de Compostela 15706 Spain Details
Hospital Universitario Virgen del Rocío Sevilla 41013 Spain Details
Hospital Universitari Joan XXIII de Tarragona Tarragona 43005 Spain Details
Hospital Clinico Universitario de Valencia Valencia 46010 Spain Details
Hospital Universitario Dr. Peset Valencia 46017 Spain Details
Hospital Universitari i Politècnic La Fe Valencia CP 46026 Spain Details
Chang Gung Medical Foundation - Kaohsiung Branch Kaohsiung Niaosong District 83301 Taiwan Details
China Medical University Hospital Taichung 40447 Taiwan Details
National Cheng Kung University Hospital Tainan 704 Taiwan Details
National Taiwan University Hospital Taipei 100 Taiwan Details
Taipei Veterans General Hospital Taipei 11217 Taiwan Details
Chang Gung Medical Foundation - Linkou Branch Taoyuan 33305 Taiwan Details
Cherkasy Regional Oncology Dispensary Cherkasy 18009 Ukraine Details
Poltava Regional Clinical Hospital named after M. V. Sklifosovskoho Poltava 36011 Ukraine Details
Vinnitsa Regional Clinical Hospital im. N.I. Pirogov Vinnytsia 21018 Ukraine Details
Zhitomir Regional Clinical Hospital Zhytomyr 10002 Ukraine Details
Maidstone and Tunbridge Wells NHS Trust - Maidstone Hospital Maidstone ME16 9QQ United Kingdom Details
*Shaded cells indicate that there was no data available from for the field