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| NCT ID | NCT02788279 |
| Title | A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants With Metastatic Colorectal Adenocarcinoma |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | ITA | GBR | ESP | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | United States | Details | |
| Yale Cancer Center; Medical Oncology | New Haven | Connecticut | 06520 | United States | Details | |
| Georgetown University | Washington | District of Columbia | 20007 | United States | Details | |
| Florida Cancer Specialists; SCRI | Fort Myers | Florida | 33901 | United States | Details | |
| Cancer Specialists; North Florida ;Jacksonville (AC Skinner Pkwy) | Jacksonville | Florida | 32256 | United States | Details | |
| Florida Cancer Specialists. | Saint Petersburg | Florida | 33705 | United States | Details | |
| Ingalls Cancer Research Center | Harvey | Illinois | 60426 | United States | Details | |
| Southdale Cancer Clinic U of M Medical Center, Fairview- Edina | Edina | Minnesota | 55435 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| North Shore Hem Onc Associates | East Setauket | New York | 11733 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| INTEGRIS Cancer Inst of OK | Oklahoma City | Oklahoma | 73142 | United States | Details | |
| University of Pittsburgh Cancer Institute; Division of Medical Oncology | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| SCRI Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | United States | Details | |
| Sarah Cannon Research Inst. | Nashville | Tennessee | 37203 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Medical Oncology Associates | Spokane | Washington | 99208 | United States | Details | |
| Port Macquarie Base Hospital;North Coast Cancer Institute | Port Macquarie | New South Wales | 2444 | Australia | Details | |
| Northern Cancer Institute | St Leonards | New South Wales | 2065 | Australia | Details | |
| Sydney Adventist Hospital; Clinical Trial Unit | Sydney | New South Wales | 2076 | Australia | Details | |
| Monash Medical Centre; Oncology | Clayton | Victoria | 3168 | Australia | Details | |
| Peninsula and South Eastern Haematology and Oncology Group | Frankston | Victoria | 3199 | Australia | Details | |
| Austin Health; Cancer Clinical Trial Centre | Heidelberg | Victoria | 3084 | Australia | Details | |
| Imeldaziekenhuis | Bonheiden | 2820 | Belgium | Details | ||
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| GHdC Site Notre Dame | Charleroi | 6000 | Belgium | Details | ||
| AZ Groeninge | Kortrijk | 8500 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Tom Baker Cancer Centre-Calgary | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Cross Cancer Institute; Clinical Trials | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| BCCA-Vancouver Cancer Centre | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| The Ottawa Hospital | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Health Sciences Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| McGill University Health Center, Cedar Cancer Center | Montreal | Quebec | H3G 1A4 | Canada | Details | |
| Hopital du Sacre-Coeur | Montreal | Quebec | J4B 5Z7 | Canada | Details | |
| CHU de Québec | Quebec City | Quebec | G1J 1Z4 | Canada | Details | |
| Queen Mary Hospital; Dept. of Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Tuen Mun Hospital; Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hosp; Dept. Of Clinical Onc | Shatin | Hong Kong | Details | |||
| Azienda Osp Uni Seconda Università Degli Studi Di Napoli; Unità Operativa Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| A.O. Universitaria Policlinico Di Modena; Oncologia | Modena | Emilia-Romagna | 41100 | Italy | Details | |
| Istit. Naz. per la Ricerca sul Cancro - Az. Osped. S. Martino | Genova | Liguria | 16132 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | Milano | Lombardia | 20133 | Italy | Details | |
| Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia | Milano | Lombardia | 20162 | Italy | Details | |
| IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia | San Giovanni Rotondo | Puglia | 71013 | Italy | Details | |
| A.O. Universitaria Pisana; Oncologia | Pisa | Toscana | 56100 | Italy | Details | |
| National Cancer Center | Gyeonggi-do | 10408 | Korea, Republic of | Details | ||
| Chonnam National University Hwasun Hospital | Jeollanam-do | 58128 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Asan Medical Center - Oncology | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Yonsei University Health System/Severance Hospital | Seoul | 120-752 | Korea, Republic of | Details | ||
| Centrum Onkologii im. Prof. F. Lukaszczyka w Bydgoszczy | Bydgoszcz | 85-796 | Poland | Details | ||
| Uniwersyteckie Centrum Kliniczne; Klinika Onkologii i Radioterapii | Gdańsk | 80-214 | Poland | Details | ||
| Szpitale Pomorskie Sp. z o. o. | Gdynia | 81-519 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Kliniki Onkologii | Krakow | 31-531 | Poland | Details | ||
| Woj.Wielospecjalistyczne Centrum Onkologii i Traumatologii; Oddz.Hematologii Pododz.Chemioterapii | Lodz | 93-513 | Poland | Details | ||
| Arkhangelsk Regional Clinical Oncology Dispensary | Arkhangelsk | 163045 | Russian Federation | Details | ||
| N.N.Burdenko Main Military Clinical Hospital; Oncology Dept | Moscow | 105229 | Russian Federation | Details | ||
| BHI of Omsk region Clinical Oncology Dispensary | Omsk | 644013 | Russian Federation | Details | ||
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico San Carlos; Servicio de Oncologia | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre; Servicio de Oncologia | Madrid | 28041 | Spain | Details | ||
| Hospital de Navarra; Servicio de Oncologia | Navarra | 31008 | Spain | Details | ||
| Hospital Clínico Universitario de Valencia; Servicio de Oncología | Valencia | 46010 | Spain | Details | ||
| Birmingham Heartlands Hospital; Dept of Oncology | Birmingham | B9 5SS | United Kingdom | Details | ||
| Royal Marsden Hospital - Fulham; Oncology Department | London | SW3 6JJ | United Kingdom | Details | ||
| The Christie; GI Research Office | Manchester | M20 4BX | United Kingdom | Details | ||
| Churchill Hospital; Department of Oncology | Oxford | OX3 7LE | United Kingdom | Details | ||
| Queen's Hospital | Romford | RM7 0AG | United Kingdom | Details | ||
| Weston Park Hospital; Cancer Clinical Trials Centre | Sheffield | S10 2SJ | United Kingdom | Details | ||
| Royal Marsden Hospital; Dept of Medical Oncology | Sutton | SM2 5PT | United Kingdom | Details |