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| NCT ID | NCT02924883 |
| Title | A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy (KATE2) |
| Acronym | KATE2 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | GBR | ESP | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Breastlink Med Group Inc | Orange | California | 92868 | United States | Details | |
| University of Colorado | Aurora | Colorado | 80045 | United States | Details | |
| MedStar Georgetown University Hospital (Lombardi Comprehensive Cancer Center) | Washington | District of Columbia | 20007 | United States | Details | |
| SCRI Florida Cancer Specialists South | Fort Myers | Florida | 33916 | United States | Details | |
| Florida Cancer Specialists; Saint Petersburg | Saint Petersburg | Florida | 33719 | United States | Details | |
| Northside Hospital | Atlanta | Georgia | 30342 | United States | Details | |
| Johns Hopkins Univ Med Center | Baltimore | Maryland | 21231 | United States | Details | |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | United States | Details | |
| Laura and ISAAC Perlmutter Cancer Center at NYU Langone. | New York | New York | 10016 | United States | Details | |
| Ohio State Uni Medical Center | Columbus | Ohio | 43210 | United States | Details | |
| Magee Womens Hospital | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | United States | Details | |
| SCRI Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | United States | Details | |
| Tennessee Oncology; Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| University of Washington | Seattle | Washington | 98195 | United States | Details | |
| St George Hospital; Cancer Care Centre | Kogarah | New South Wales | 2217 | Australia | Details | |
| Calvary Mater Newcastle | Waratah | New South Wales | 2298 | Australia | Details | |
| Princess Alexandra Hospital Woolloongabba; Clinical Hematology and Medical Oncology | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Peter MacCallum Cancer Center | East Melbourne | Victoria | 3002 | Australia | Details | |
| Peninsula and South Eastern Haematology and Oncology Group | Frankston | Victoria | 3199 | Australia | Details | |
| Sunshine Hospital | St Albans | Victoria | 3021 | Australia | Details | |
| St John of God Hospital; Bendat Cancer Centre | Subiaco | Western Australia | 6008 | Australia | Details | |
| Lakeridge Health Oshawa; Oncology | Oshawa | Ontario | L1G 2B9 | Canada | Details | |
| The Ottawa Hospital Cancer Centre; Oncology | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| McGill University; Sir Mortimer B Davis Jewish General Hospital; Oncology | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| McGill University; Glen Site; Oncology | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Hopital du Saint Sacrement | Quebec City | Quebec | G1S 4L8 | Canada | Details | |
| HELIOS Klinikum Berlin-Buch; Klinik für Gynäkologie und Geburtshilfe | Berlin | 13125 | Germany | Details | ||
| Studienzentrum Berlin City | Berlin | 14169 | Germany | Details | ||
| Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum | Essen | 45136 | Germany | Details | ||
| Praxis für Interdisziplinäre Onkologie und Hämatologie GbR | Freiburg | 79110 | Germany | Details | ||
| Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| Institut für Versorgungsforschung in der Onkologie GbR Koblenz | Koblenz | 56068 | Germany | Details | ||
| IRCCS Istituto Nazionale Tumori Fondazione Pascale; Oncologia Medica A | Napoli | Campania | 80131 | Italy | Details | |
| A.O.U Policlinico S. Orsola Malpighi di Bologna U.O di Medicina Interna Borghi - Pad.2 | Bologna | Emilia-Romagna | 40138 | Italy | Details | |
| Ospedale Regionale Di Parma; Divisione Di Oncologia Medica | Parma | Emilia-Romagna | 43100 | Italy | Details | |
| Centro Di Riferimento Oncologico; SOC Oncologia Medica C | Aviano | Friuli-Venezia Giulia | 33081 | Italy | Details | |
| Centro Catanese Di Oncologia; Oncologia Medica | Catania | Sicilia | 95126 | Italy | Details | |
| Ospedale Santo Stefano, Azienda USL Centro Prato | Prato | Toscana | 59100 | Italy | Details | |
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | (0)6351 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Barcelona | 08035 | Spain | Details | ||
| Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología | La Coruña | 15006 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia | Valencia | 46010 | Spain | Details | ||
| Hospital Arnau de Vilanova (Valencia) Servicio de Oncologia | Valencia | 46015 | Spain | Details | ||
| Changhua Christian Hospital; Dept of Surgery | Changhua | 500 | Taiwan | Details | ||
| Kaohsiung Medical Uni Chung-Ho Hospital; Dept of Surgery | Kaohsiung | 807 | Taiwan | Details | ||
| China Medical University Hospital; Surgery | Taichung | 404 | Taiwan | Details | ||
| Chi-Mei Medical Center | Tainan | 736 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology | Taipei City | 11259 | Taiwan | Details | ||
| VETERANS GENERAL HOSPITAL; Department of General Surgery | Taipei | 00112 | Taiwan | Details | ||
| National Taiwan Uni Hospital; General Surgery | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Memorial Hospital - Linkou | Taoyuan | 333 | Taiwan | Details | ||
| Royal United Hospital; Oncology Department | Bath | BA1 3NG | United Kingdom | Details | ||
| Beatson West of Scotland Cancer Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| Royal Free Hospital; Dept of Oncology | London | NW3 2QG | United Kingdom | Details | ||
| Royal Marsden Hosp NHS Fnd; Breast Unit | London | SW3 6JJ | United Kingdom | Details | ||
| Christie Hospital; Breast Cancer Research Office | Manchester | M20 4QL | United Kingdom | Details | ||
| Nottingham City Hospital | Nottingham | NG5 1PB | United Kingdom | Details | ||
| Weston Park Hospital; Cancer Clinical Trials Centre | Sheffield | S10 2SJ | United Kingdom | Details | ||
| Royal Marsden Hosp NHS Fnd; Medicine - Breast Unit | Sutton | SM2 5PT | United Kingdom | Details | ||
| Singleton Hospital; Pharmacy | Swansea | SA2 8QA | United Kingdom | Details |