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| NCT ID | NCT03042611 |
| Title | Efficacy and Safety Trial of Apatinib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Patients With Gastric Cancer |
| Acronym | ANGEL |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | LSK BioPartners Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | DEU |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Phoenix | Scottsdale | Arizona | 85259 | United States | Details | |
| Highlands Oncology Group | Rogers | Arkansas | 72758 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | United States | Details | |
| Hudson Valley Cancer Centre | Hawthorne | New York | 10532 | United States | Details | |
| Centre Hospitalier Franco-Britannique; Oncologie Médicale | Levallois-Perret | 92300 | France | Details | ||
| Centre Leon-Berard (CLB) | Lyon | 69008 | France | Details | ||
| Institut Regional du Cancer Montpellier (ICM) | Montpellier | 34298 | France | Details | ||
| Centre Antoine-Lacassagne | Nice | 06189 | France | Details | ||
| Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Charite - Universitaetsmedizin Berlin - Medizinische Klinik mit Schwerpunkt Haematologie, Onkologie und Tumorimmunologie | Berlin | 13353 | Germany | Details | ||
| "Institut für Klinisch-Onkologische Forschung (IKF) Krankenhaus Nordwest gGmbH UCT - Universitäres Centrum für Tumorerkrankungen Frankfurt | Frankfurt | 60488 | Germany | Details | ||
| Facharztzentrum Eppendorf - Haematologisch-Onkologische Praxis Eppendorf (HOPE) | Hamburg | 20249 | Germany | Details | ||
| Universitätsklinik Marburg, Klinik fur Innere Medizin, Schwerpunkt Haematologie, Onkologie und Immunologie | Marburg | 35043 | Germany | Details | ||
| Magna Graecia University- Department of Experimental and Clinical Medicine | Catanzaro | 88100 | Italy | Details | ||
| U.O Di Oncologia Ospedale Degli Infermi | Faenza | 48018 | Italy | Details | ||
| Fondazione IRCCS-Istituto Nazionale Tumori | Milano | 20133 | Italy | Details | ||
| Policlinico di Modena-Azienda Ospedaliero Universitaria di Modena.Oncologia ed Ematologia. | Modena | 41124 | Italy | Details | ||
| Veneto Oncology Institute (IOV-IRCCS), Melanoma & Esophageal Oncology Unit | Padova | 35128 | Italy | Details | ||
| Ospedale di Piacenza - Oncology and heamatology | Piacenza | 29121 | Italy | Details | ||
| Ospedale "Felice Lotti" | Pontedera | 56025 | Italy | Details | ||
| IRCCS/Arcispedale Santa Maria Nuova | Reggio Emilia | 42123 | Italy | Details | ||
| Rimini Hospital | Rimini | 47923 | Italy | Details | ||
| Ospedali Riuniti di Ancona - SOD Clinica Oncologica | Torrette | 60126 | Italy | Details | ||
| Hyogo Cancer Center | Hyogo | Akasi-city | 673-0021 | Japan | Details | |
| Chiba Cancer Center | Chiba | Chiba City | 260-8717 | Japan | Details | |
| National Cancer Center Hospital | Tokyo | Chuo-ku | 104-0045 | Japan | Details | |
| Kyushu University Hospital | Fukuoka | Higashi-ku | 812-8582 | Japan | Details | |
| National Cancer Center Hospital East | Chiba | Kashiwa | 277-8577 | Japan | Details | |
| St. Marianna University School of Medicine Hospital | Kanagawa | Kawasaki-shi | 216-8511 | Japan | Details | |
| Saitama Cancer Center | Saitama | Kitaadachi-gun | 362-0806 | Japan | Details | |
| Japan Community Health Care Organization Kyushu Hospital | Fukuoka | Kitakyushu-shi | 806-8501 | Japan | Details | |
| The Cancer Institute Hospital of Japanese Foundation For Cancer Research | Tokyo | Koto-ku | 135-8550 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center | Ehime | Matsuyama | 791-0280 | Japan | Details | |
| Saku Central Hospital Advanced Care Center | Nagano | Saku-shi | 385-0051 | Japan | Details | |
| Hokkaido University Hospital | Hokkaido | Sapporo | 060-8648 | Japan | Details | |
| Keio University Hospital | Tokyo | Shinjuku-ku | 160-8582 | Japan | Details | |
| Osaka University Hospital | Osaka | Suita | 565-0871 | Japan | Details | |
| Aichi Cancer Center Hospital | Nagoya | 464-8681 | Japan | Details | ||
| Hallym University Sacred Heart Hospital | Anyang-si | Gyeonggi-do | 14069 | Korea, Republic of | Details | |
| National Cancer Center | Goyang-si | Gyeonggi-do | 10408 | Korea, Republic of | Details | |
| Ajou University Hospital | Suwon-si | Gyonggi-do | 16499 | Korea, Republic of | Details | |
| Inje University Haeundae Paik Hospital | Busan | 48108 | Korea, Republic of | Details | ||
| Dong-A University Hospital | Busan | 49201 | Korea, Republic of | Details | ||
| Pusan National University Hospital | Busan | 49241 | Korea, Republic of | Details | ||
| Chungbuk National University Medical Center | Chuncheon | 41404 | Korea, Republic of | Details | ||
| Chungbuk National University Hospital | Chungbuk | 54907 | Korea, Republic of | Details | ||
| Kyungpook National University Medical Center | Daegu | 41404 | Korea, Republic of | Details | ||
| Keimyung University Dongsan Medical Center | Daegu | 41931 | Korea, Republic of | Details | ||
| Yeungnam University Medical Center | Daegu | 42415 | Korea, Republic of | Details | ||
| Chungnam National University Hospital | Daejeon | 35015 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Gyeonggi-do | 13620 | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Incheon | 21555 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Severence Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Veterans Health Service (VHS) Medical Center | Seoul | 05368 | Korea, Republic of | Details | ||
| ASAN Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Gangnam Severance Hospital | Seoul | 06273 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 08308 | Korea, Republic of | Details | ||
| Ulsan University Hospital | Ulsan | 44033 | Korea, Republic of | Details | ||
| Szpital Uniwersytecki w Krakowie, Odział Kliniczny Onkologii | Kraków | 31-501 | Poland | Details | ||
| Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Klinika Gastroenterologii Onkologicznej | Warszawa | 02-781 | Poland | Details | ||
| Saint Constantin Hospital (TEO HEALTH SA) | Brasov | 500091 | Romania | Details | ||
| Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj-Napoca, Sectia de Radioterapie I | Cluj-Napoca | 400015 | Romania | Details | ||
| S.C. Medisprof S.R.L. | Cluj-Napoca | 400058 | Romania | Details | ||
| Centrul de Oncologie "Sf. Nectarie", Sectia de Oncologie Medicala | Craiova | 200347 | Romania | Details | ||
| State Budgetary Healthcare Institution of Arkhangelsk Region "Arkhangelsk Clinical Oncology Dispensary" | Arkhangelsk | 163045 | Russian Federation | Details | ||
| State Healthcare Institution "Kursk Regional Clinical Oncology Dispensary" | Kursk | 305035 | Russian Federation | Details | ||
| Omsk regional clinical oncology center | Omsk | 644013 | Russian Federation | Details | ||
| Budgetary Healthcare Institution of Orel Region "Orel Oncology Dispensary" | Oryol | 302020 | Russian Federation | Details | ||
| State Budgetary Healthcare Institution of Stavropol Territory "Pyatigorsk Oncology Dispensary" | Pyatigorsk | 357502 | Russian Federation | Details | ||
| Ogarev Mordovia State University | Saransk | 430032 | Russian Federation | Details | ||
| Federal State Budgetary Educational Institution of Higher Education "Academician I.P. Pavlov First St. Petersburg State Medical University" of the Ministry of Heaithcare of the Russian Federation | St. Petersburg | 197022 | Russian Federation | Details | ||
| State Budgetary Healthcare Institution "Republican Clinical Oncology Dispensary" | Ufa | 450054 | Russian Federation | Details | ||
| Taipei Veterans General Hospital | Taipei | Beitou Dist | 11217 | Taiwan | Details | |
| Chang Gung Memorial Hospital - Linko Branch | Taoyuan | Kuei Shan Hsiang | 333 | Taiwan | Details | |
| Chi Mei Medical Center - LiouYing Branch | Tainan | Liuying DIst | 736 | Taiwan | Details | |
| Chang Gung Memorial Hospital - Kaohsiung Branch | Kaohsiung | Niaosong Dist | 83301 | Taiwan | Details | |
| Kaohsiung Medical University Hospital | Kaohsiung | Sanmin Dist | 80708 | Taiwan | Details | |
| China Medical University Hospital | Taichung | Taichung City | 40447 | Taiwan | Details | |
| National CHeng Kung University Hospital | Tainan | Tainan City | 70403 | Taiwan | Details | |
| National Taiwan University Hospital | Taipei | Zhongzheng Dist | 100 | Taiwan | Details | |
| Dnipropetrovsk Medical Academy, Department of Oncology | Dnipro | 49102 | Ukraine | Details | ||
| Communal Institution "Ivano-Frankivsk Regional Oncological Center" | Ivano-Frankivsk | 76000 | Ukraine | Details | ||
| Communal Institution "Kharkiv Regional Clinical Oncology Center ", Chemotherapy department #1, Medical Academy of Postgraduate Education, Oncology and Pediatric Oncology | Kharkiv | 61070 | Ukraine | Details | ||
| Kherson Regional Oncological Dispensary | Kherson | 73035 | Ukraine | Details | ||
| Municipal Institution Kryvyi Rig Oncology Dispensary", Chemotherapy Department | Kryvyi Rih | 50048 | Ukraine | Details | ||
| Municipal Institution "Kyiv City Clinical Oncological Center" | Kyiv | 03115 | Ukraine | Details | ||
| Communal Institution "Transcarpathian Regional Clinical Oncological Center" | Uzhhorod | 88014 | Ukraine | Details | ||
| Communal Institution "Vinnytsia Regional Clinical Oncology Dispensary" | Vinnytsia | 21029 | Ukraine | Details | ||
| State institution "Zaporizhzhia Medical Academy of Postgraduate Education MOH Ukraine", Department of oncology based on Municipal Institution "Zaporizhzhia Regional Clinical Oncology Dispensary" Zaporizhzhia Regional Assembly | Zaporizhzhia | 69040 | Ukraine | Details | ||
| Royal Marsden Hospital London | London | SW3 6JJ | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Royal Marsden Hospital Surrey | Sutton | SM2 5PT | United Kingdom | Details |