Clinical Trial Detail

NCT ID NCT03281369
Title A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) (UMBRELLA)
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Hoffmann-La Roche
Indications

gastroesophageal junction adenocarcinoma

gastric adenocarcinoma

Therapies

Atezolizumab + Cobimetinib

Atezolizumab + Cobimetinib + Fluorouracil + Leucovorin + Oxaliplatin

Atezolizumab + Fluorouracil + Leucovorin + Oxaliplatin

Atezolizumab + Linagliptin

Atezolizumab + PEGPH20

Atezolizumab + BKT140

Paclitaxel + Ramucirumab

Fluorouracil + Leucovorin + Oxaliplatin

Age Groups: senior adult

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