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| NCT ID | NCT03374488 |
| Title | Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial Carcinoma |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Incyte Corporation |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ironwood Cancer & Research Centers | Chandler | Arizona | 85224 | United States | Details | |
| University of California Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | United States | Details | |
| UCLA Hematology Oncology Santa Monica | Santa Monica | California | 90404 | United States | Details | |
| Smilow Cancer Center at Yale-New Haven | New Haven | Connecticut | 06510 | United States | Details | |
| Northside Hospital, Inc. - GCS/Annex | Atlanta | Georgia | 30341 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| Quincy Medical Group | Quincy | Illinois | 62301 | United States | Details | |
| Johns Hopkins University | Baltimore | Maryland | 21287 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | United States | Details | |
| NYU Clinical Cancer Center | New York | New York | 10016 | United States | Details | |
| Oklahoma Cancer Specialists & Research Institute | Tulsa | Oklahoma | 74146 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97210 | United States | Details | |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Medical University of South Carolina-Hollings Cancer Center | Charleston | South Carolina | 29425 | United States | Details | |
| University of Tennessee Medical Center Knoxville | Knoxville | Tennessee | 37920 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37203 | United States | Details | |
| US Oncology and Research | Fort Worth | Texas | 76177 | United States | Details | |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | United States | Details | |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | United States | Details | |
| VCU Massey Cancer Center | Richmond | Virginia | 23298 | United States | Details | |
| Southern Medical Day Care Centre | Wollongong | New South Wales | 2500 | Australia | Details | |
| Austin Health-Austin Hospital | Heidelberg | Victoria | 3084 | Australia | Details | |
| Adelaide Cancer Centre | Kurralta Park | 5037 | Australia | Details | ||
| Macquarie University Hospital | Macquarie Park | 2109 | Australia | Details | ||
| London Health Sciences Centre | London | Ontario | N6A 4L6 | Canada | Details | |
| The Ottawa Hospital Cancer Centre | Ottawa | Ontario | K1H 8L6 | Canada | Details | |
| Sunnybrook Research Institute | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| CIUSSS - Hopital Maisonneuve- Rosemont | Montréal | Quebec | H1T 2M4 | Canada | Details | |
| CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont | Montréal | Quebec | H1T 2M4 | Canada | Details | |
| CHU de Quebec-Universite Laval-Hotel Dieu de Quebec | Québec | Quebec | G1R 3S1 | Canada | Details | |
| CHU de Quebec-Universite Laval-Hotel Dieu de Quebec | Quebec | G1R 3S1 | Canada | Details | ||
| Aalborg University Hospital | Aalborg | 9000 | Denmark | Details | ||
| Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
| Herlev Hospital | Herlev | 2730 | Denmark | Details | ||
| Sjaellands Universitetshospital Naestved | Næstved | 4700 | Denmark | Details | ||
| Institut de Cancerologie de l Ouest Site Paul Papin | Angers | 49055 | France | Details | ||
| Clinique Sainte Catherine | Avignon | 84918 | France | Details | ||
| Centre de Lutte Contre le Cancer Francois Baclesse | Caen | 14000 | France | Details | ||
| Clinique Victor Hugo | Le Mans | 72000 | France | Details | ||
| Centre Oscar Lambret | Lille | 59020 | France | Details | ||
| Centre Leon Berard | Lyon | 69008 | France | Details | ||
| Institut du Cancer de Montpellier | Montpellier | 34298 | France | Details | ||
| Hopital Cochin | Paris | 75014 | France | Details | ||
| Hopital Saint Louis | Paris | 75475 | France | Details | ||
| Institut Jean Godinot | Reims | 51726 | France | Details | ||
| Centre Medico-Chirurgical Foch | Suresnes | 92151 | France | Details | ||
| C.H.U. de Tours - Hopital Bretonneau | Tours | 37044 | France | Details | ||
| Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Universitaetsklinikum Schleswig-Holstein. Campus Luebeck | Luebeck | Schleswig Holstein | 23538 | Germany | Details | |
| Universitaetsklinikum Duesseldorf | Duesseldorf | 40225 | Germany | Details | ||
| Universitatsklinikum Hamburg-Eppendorf | Hamburg | 20246 | Germany | Details | ||
| Universitaetsklinikum Jena | Jena | 07747 | Germany | Details | ||
| Universitaetsklinikum Magdeburg A.o.R. | Magdeburg | 39120 | Germany | Details | ||
| Klinikum rechts der Isar der Technischen Universitat | Muenchen | 81675 | Germany | Details | ||
| Universitaetsklinikum Tuebingen | Tuebingen | 72076 | Germany | Details | ||
| Orszagos Onkologiai Intezet | Budapest | 1122 | Hungary | Details | ||
| Uzsoki Utcai Korhaz | Budapest | 1145 | Hungary | Details | ||
| Somogy Megyei Kaposi Mor Oktato Korhaz | Kaposvár | 7400 | Hungary | Details | ||
| Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz | Miskolc | 3526 | Hungary | Details | ||
| Pecsi Tudomanyegyetem AOK | Pécs | 7624 | Hungary | Details | ||
| Jasz - Nagykun Szolnok megyei Hetenyi Geza Korhaz - Rendelointezet | Szolnok | 5004 | Hungary | Details | ||
| Cork University Hospital | Cork | Ireland | Details | |||
| Beaumont Hospital | Dublin | 00009 | Ireland | Details | ||
| Adelaide & Meath Hospital (Incl NCH) | Dublin | 00024 | Ireland | Details | ||
| University College Hospital Galway | Galway | H91YR71 | Ireland | Details | ||
| University Hospital Limerick | Limerick | V94F858 | Ireland | Details | ||
| Waterford Regional Hospital | Waterford | X91ER8E | Ireland | Details | ||
| Soroka Medical Center | Be'er Sheva | 8410101 | Israel | Details | ||
| Rambam Medical Center | Haifa | 31096 | Israel | Details | ||
| Meir Medical Center | Kfar Saba | 4428164 | Israel | Details | ||
| Rabin Medical Center | Petach-Tikwa | 49100 | Israel | Details | ||
| Chaim Sheba Medical Center | Ramat Gan | 52621 | Israel | Details | ||
| Sourasky Medical Center | Tel Aviv | 6423906 | Israel | Details | ||
| Assaf Harofeh Medical Center | Zerifin | 70300 | Israel | Details | ||
| Medical Oncology Ospedale San Donato | Arezzo | 52100 | Italy | Details | ||
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | 47014 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione Pascale | Napoli | 80131 | Italy | Details | ||
| Istituto Oncologico Veneto | Padova | 35128 | Italy | Details | ||
| Nagoya University Hospital | Nagoya | Aichi | 466-8560 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| University of Tsukuba Hospital | Tsukuba | Ibaraki | 305-8576 | Japan | Details | |
| Nara Medical University Hospital | Kashihara | Nara | 634-8522 | Japan | Details | |
| Yamaguchi University Hospital | Ube | Yamaguchi | 755-8505 | Japan | Details | |
| Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| Medical Hospital, Tokyo Medical And Dental University | Tokyo | 113-8519 | Japan | Details | ||
| Yusen Logistics Co Ltd,. Haneda Logistics Center (MSD DC) | Tokyo | 144-0042 | Japan | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Antoni van Leeuwenhoek Ziekenhuis | Amsterdam | 1066 CX | Netherlands | Details | ||
| VU University Medical Center | Amsterdam | 1081 HV | Netherlands | Details | ||
| Amphia Ziekenhuis | Breda | 4819 EV | Netherlands | Details | ||
| Catharina Ziekenhuis | Eindhoven | 5623 EJ | Netherlands | Details | ||
| University Medical Center Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Leningrad Regional Oncology Dispensary | Saint Petersburg | Leningrad Region, Vsevolozhsky District | 188663 | Russian Federation | Details | |
| Ivanovo Regional Oncology Dispensary | Ivanovo | 153013 | Russian Federation | Details | ||
| N.N. Blokhin NMRCO | Moscow | 115478 | Russian Federation | Details | ||
| Russian Scientific Center of Roentgenoradiology | Moscow | 117997 | Russian Federation | Details | ||
| National Medical Research Radiological Centre | Moscow | 125284 | Russian Federation | Details | ||
| Ryazan Regional Clinical Oncology Dispensary | Ryazan' | 390046 | Russian Federation | Details | ||
| Pokrovskaya City Hospital | Saint Petersburg | 199106 | Russian Federation | Details | ||
| Clinic of Bashkortostan State Medical University | Ufa | 450081 | Russian Federation | Details | ||
| Hospital del Mar | Barcelona | 08003 | Spain | Details | ||
| Hospital Vall D Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau | Barcelona | 08041 | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
| MD Anderson Cancer Center Madrid | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria | Málaga | 29010 | Spain | Details | ||
| Hospital Clinico Universitario de Santiago | Santiago De Compostela | 15706 | Spain | Details | ||
| Instituto Valenciano de Oncologia | Valencia | 46009 | Spain | Details | ||
| Chang Gung Medical Foundation. Kaohsiung Branch | Kaohsiung | 833 | Taiwan | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Adana Sehir Hastanesi | Adana | 01370 | Turkey | Details | ||
| Dr. Abdurrahman Yurtaslan Ankara Onkoloji EAH | Ankara | 06200 | Turkey | Details | ||
| Akdeniz Universitesi Tip Fakultesi | Antalya | 07059 | Turkey | Details | ||
| Pamukkale Unv. Tip Fak. | Denizli | 20070 | Turkey | Details | ||
| Trakya Universitesi Tip Fakultesi | Edirne | 22030 | Turkey | Details | ||
| Marmara Universitesi Pendik Arastirma ve Uyg. Hastanesi | Istanbul | 34899 | Turkey | Details | ||
| Dokuz Eylul University Faculty of Medicine | İzmir | 35340 | Turkey | Details | ||
| Samsun Medical Park Hastanesi | Samsun | 55200 | Turkey | Details | ||
| Royal Marsden NHS Trust | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Queen Elizabeth Hospital | Birmingham | B15 2TH | United Kingdom | Details | ||
| Barts Health NHS Trust - St Bartholomew s Hospital | London | EC1A 7BE | United Kingdom | Details | ||
| Royal Free London NHS Foundation Trust | London | NW3 2QG | United Kingdom | Details | ||
| Imperial College Healthcare NHS Trust | London | W6 8RF | United Kingdom | Details | ||
| Plymouth Hospitals NHS Trust | Plymouth | PL6 8DH | United Kingdom | Details | ||
| Sunderland Royal Hospital | Sunderland | SR4 7TP | United Kingdom | Details |