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| NCT ID | NCT03523585 |
| Title | DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Daiichi Sankyo, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ironwood Cancer Research Centers | Chandler | Arizona | 85224-5665 | United States | Details | |
| UCLA Hematology Oncology - Main Site | Los Angeles | California | 90095 | United States | Details | |
| Pacific Cancer Care | Monterey | California | 93940 | United States | Details | |
| Sharp Memorial Hospital | San Diego | California | 92123 | United States | Details | |
| Innovative Clinical Research Institute | Whittier | California | 90603 | United States | Details | |
| Smilow Cancer Hospital at Yale New Haven | New Haven | Connecticut | 06510 | United States | Details | |
| Washington Cancer Institute | Washington | District of Columbia | 20010 | United States | Details | |
| Florida Cancer Specialists-Broadway | Fort Myers | Florida | 33901 | United States | Details | |
| Piedmont Cancer Institute, PC | Atlanta | Georgia | 30318 | United States | Details | |
| Kapiolani Medical Center for Women and Children/Univ of HI | Honolulu | Hawaii | 96826 | United States | Details | |
| Loyola University Health System | Maywood | Illinois | 60153 | United States | Details | |
| Community Hospital | Munster | Indiana | 46321 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | United States | Details | |
| Maine Center for Cancer Medicine | Scarborough | Maine | 04074 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States | Details | |
| Cornell-Beshore Cancer Institute | Joplin | Missouri | 64804 | United States | Details | |
| Saint Luke's Cancer Institute | Kansas City | Missouri | 64111 | United States | Details | |
| Health Midwest Ventures Group, Inc d/b/a HCA MidAmerica Division, LLC | Kansas City | Missouri | 64132 | United States | Details | |
| Washington University | Saint Louis | Missouri | 63110 | United States | Details | |
| North Shore Hematology Oncology Associates, PC | East Setauket | New York | 11733 | United States | Details | |
| Memorial Sloan-Kettering Cancer Center (MSKCC) - New York | New York | New York | 10065 | United States | Details | |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267-0502 | United States | Details | |
| Cleveland Clinic Main Campus | Cleveland | Ohio | 44195 | United States | Details | |
| The Ohio State University | Columbus | Ohio | 43235 | United States | Details | |
| Dayton Physicians, LLC | Kettering | Ohio | 45409 | United States | Details | |
| Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | United States | Details | |
| UPMC Cancer Center | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| Tennessee Oncology, PLLC Chattanooga | Chattanooga | Tennessee | 37404 | United States | Details | |
| The West Clinic | Germantown | Tennessee | 38138 | United States | Details | |
| SCRI - Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| UT Southwestern Medical Center | Dallas | Texas | 75390-8857 | United States | Details | |
| MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| The Methodist Hospital Research Institute | Houston | Texas | 77030 | United States | Details | |
| The University of Texas Health Science Center at Tyler | Tyler | Texas | 75708 | United States | Details | |
| Community Cancer Trials of Utah | Ogden | Utah | 84405 | United States | Details | |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | United States | Details | |
| MultiCare Health System Institute for Research and Innovation | Tacoma | Washington | 98405 | United States | Details | |
| St Vincent's Hospital Sydney | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Liverpool Hospital | Liverpool | New South Wales | 2170 | Australia | Details | |
| Macquarie University Hospital | Sydney | New South Wales | 2109 | Australia | Details | |
| The Tweed Hospital | Tweed Heads | New South Wales | 2485 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Ashford Cancer Centre Research | Kurralta Park | South Australia | 5037 | Australia | Details | |
| Box Hill Hospital | Box Hill | Victoria | 3128 | Australia | Details | |
| Frankston Hospital | Frankston | Victoria | 3199 | Australia | Details | |
| Peninsula and South Eastern Haematology & Oncology Group | Frankston | Victoria | 3199 | Australia | Details | |
| Austin Health | Heidelberg | Victoria | 3084 | Australia | Details | |
| Peter MacCallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| Sunshine Hospital | Saint Albans | Victoria | 3021 | Australia | Details | |
| South West Oncology | Warrnambool | Victoria | 3280 | Australia | Details | |
| Ballarat Oncology & Haematology Service | Wendouree | Victoria | 3355 | Australia | Details | |
| St John of God Subiaco Hospital | Subiaco | Western Australia | 6008 | Australia | Details | |
| Calvary North Adelaide Hospital | Bruce | 2614 | Australia | Details | ||
| Universitair Ziekenhuis Brussel | Bruxelles | 1090 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Bruxelles | 1200 | Belgium | Details | ||
| AZ Maria Middelares | Gent | 9000 | Belgium | Details | ||
| Az Groeninge | Kortrijk | 8500 | Belgium | Details | ||
| UZ Leuven | Leuven | 3000 | Belgium | Details | ||
| CHU UCL Namur site de Sainte Elisabeth | Namur | 5000 | Belgium | Details | ||
| NOB - Núcleo de Oncologia da Bahia | Salvador | Bahia | 40170-110 | Brazil | Details | |
| AMO - Assistência Multidisciplinar em Oncologia | Salvador | Bahia | 41950-640 | Brazil | Details | |
| Pronutrir | Fortaleza | Ceará | 60810-180 | Brazil | Details | |
| Oncobio Servicos de Saude | Nova Lima | Minas Gerais | 34000 | Brazil | Details | |
| HGB - Hospital Giovanni Battista - Mãe de Deus Center | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details | |
| CliniOnco - Tratamento Integrado do Câncer | Porto Alegre | Rio Grande Do Sul | 90430-090 | Brazil | Details | |
| Escosteguy Barrios, Carlos Henrique | Porto Alegre | Rio Grande Do Sul | 90610-000 | Brazil | Details | |
| Hospital Nossa Senhora da Conceição | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| Clínica de Neoplasias Litoral Ltda. | Itajaí | Santa Catarina | 88301-220 | Brazil | Details | |
| CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia | Santo André | Sao Paulo | 09060-650 | Brazil | Details | |
| IBCC - Instituto Brasileiro de Controle do Câncer | São Paulo | Sao Paulo | 03102-002 | Brazil | Details | |
| COI - Clínicas Oncológicas Integradas | Rio De Janeiro | 22793-080 | Brazil | Details | ||
| Sociedade Beneficiente de Senhoras Hospital Sírio Libanês | São Paulo | 01308 | Brazil | Details | ||
| A. C. Camargo Cancer Center | São Paulo | 01509-900 | Brazil | Details | ||
| Fakultni nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
| Fakultni nemocnice Olomouc | Olomouc | 775 20 | Czechia | Details | ||
| Fakultni nemocnice v Motole | Prague 5 | 150 06 | Czechia | Details | ||
| Nemocnice Na Bulovce | Praha | 180 81 | Czechia | Details | ||
| Hôpital Nord - CHU Marseille | Marseille cedex 20 | Bouches-du-Rhône | 13915 | France | Details | |
| Centre François Baclesse | Caen Cedex 05 | Calvados | 14076 | France | Details | |
| CARIO - Centre Armoricain de Radiothérapie, Imagerie médicale et Oncologie | Plérin | Cotes d'Armor | 22190 | France | Details | |
| Centre Georges François Leclerc | Dijon cedex | Côte-d'Or | 21079 | France | Details | |
| CHU Besançon - Hôpital Jean Minjoz | Besançon | Doubs | 25030 | France | Details | |
| CHU Brest - Hôpital Morvan | Brest Cedex | Finistere | 29609 | France | Details | |
| Hôpital Privé d'Antony | Antony | Hauts De Seine | 92160 | France | Details | |
| Centre René Huguenin | Saint-Cloud | Hauts De Seine | 92110 | France | Details | |
| Clinique Clementville | Montpellier | Herault | 34070 | France | Details | |
| Institut Régional du Cancer de Montpellier | Montpellier | Herault | 34298 | France | Details | |
| CRLCC Eugene Marquis | Rennes cedex | Ille Et Vilaine | 35042 | France | Details | |
| Centre Oscar Lambret | Lille cedex | Nord | 59020 | France | Details | |
| Centre de cancerologie les Dentellieres | Valenciennes | Nord | 59300 | France | Details | |
| Institut Curie - site de Paris | Paris Cedex 05 | Paris | 75005 | France | Details | |
| Centre Hospitalier de la côte Basque | Bayonne Cedex | Pyrenees Atlantiques | 64109 | France | Details | |
| Centre Hospitalier Lyon Sud | Pierre Benite cedex | Rhone | 69495 | France | Details | |
| Clinique Victor Hugo - Centre Jean Bernard | Le Mans Cedex 02 | Sarthe | 72015 | France | Details | |
| Centre Henri Becquerel | Rouen | Seine Maritime | 76038 | France | Details | |
| Institut Sainte Catherine | Avignon Cedex 9 | Vaculuse | 84918 | France | Details | |
| Institut Gustave Roussy | Villejuif cedex | Val De Marne | 94805 | France | Details | |
| Institut Régional du Cancer de Montpellier | Montpellier | 34298 | France | Details | ||
| Institut Curie - site de Paris | Paris | 75005 | France | Details | ||
| Hopital Tenon | Paris | 75020 | France | Details | ||
| Klinikum rechts der Isar der TU Muenchen | Muenchen | Bayern | 81675 | Germany | Details | |
| Marienhospital Bottrop gGmbH | Bottrop | Rheinland Pfalz | 46236 | Germany | Details | |
| Universitaetsklinikum Schleswig-Holstein - Campus Luebeck | Luebeck | Schleswig Holstein | 23538 | Germany | Details | |
| Helios-Kliniken Berlin-Buch | Berlin | 13125 | Germany | Details | ||
| Universitaetsklinikum Duesseldorf AoeR | Düsseldorf | 40225 | Germany | Details | ||
| Universitaetsklinikum Erlangen | Erlangen | 91054 | Germany | Details | ||
| Kliniken Koeln | Koeln | 51067 | Germany | Details | ||
| Universitaetsklinikum Leipzig AoeR | Leipzig | 04103 | Germany | Details | ||
| Klinikum der Universitaet Muenchen - Campus Grosshardern | Munich | 81377 | Germany | Details | ||
| Universitaetsklinikum Muenster | Müenster | 48149 | Germany | Details | ||
| Haematologisch-Onkologische Schwerpunktpraxis | Troisdorf | 53840 | Germany | Details | ||
| 251 General Air Force Hospital | Athens | 11525 | Greece | Details | ||
| General Hospital of Athens "Alexandra" | Athens | 11528 | Greece | Details | ||
| General Oncology Hospital of Kifissia " Agioi Anargyroi" | Athens | 14564 | Greece | Details | ||
| University General Hospital of Heraklion | Heraklion | 71110 | Greece | Details | ||
| Euromedica General Clinic Thessaloniki | Thessaloníki | 54645 | Greece | Details | ||
| Rambam Health Care Center | Haifa | 3109601 | Israel | Details | ||
| Shaare Zedek Medical Center | Jerusalem | 9103102 | Israel | Details | ||
| Hadassah University Hospital - Ein Kerem | Jerusalem | 9112001 | Israel | Details | ||
| Sapir Medical Center, Meir Hospital | Kfar Saba | 4428164 | Israel | Details | ||
| Rabin Medical Center-Beilinson Campus | Petah tikva | 49100 | Israel | Details | ||
| Chaim Sheba Medical Center | Ramat Gan | 52363 | Israel | Details | ||
| Tel Aviv Sourasky Medical Center | Tel Aviv | 6423906 | Israel | Details | ||
| Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo) | Monza | Milano | 20900 | Italy | Details | |
| IRCCS Centro di Riferimento Oncologico | Aviano | Pordenone | 33081 | Italy | Details | |
| Ospedale Sacro Cuore Don Calabria | Negrar | Verona | 37024 | Italy | Details | |
| Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII) | Bergamo | 24127 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Arcispedale Sant'Anna | Cona | 44124 | Italy | Details | ||
| Istituto Nazionale per la Ricerca sul Cancro di Genova | Genova | 16132 | Italy | Details | ||
| Azienda Ospealiera della Provincia di Lecco | Lecco | 23900 | Italy | Details | ||
| Azienda Ospedaliera Ospedali Riuniti Papardo-Piemonte | Messina | 98158 | Italy | Details | ||
| Ospedale San Raffaele | Milano | 20132 | Italy | Details | ||
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | 20133 | Italy | Details | ||
| IEO Istituto Europeo di Oncologia | Milano | 20141 | Italy | Details | ||
| A.O.U. Policlinico di Modena | Modena | 41124 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione G. Pascale | Napoli | 80131 | Italy | Details | ||
| IOV - Istituto Oncologico Veneto IRCCS | Padova | 35128 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Parma | Parma | 43100 | Italy | Details | ||
| Fondazione IRCCS Policlinico San Matteo | Pavia | 27100 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Pisana | Pisa | 56126 | Italy | Details | ||
| Azienda Ospedaliera Città della Salute e della Scienza di Torino | Torino | 10126 | Italy | Details | ||
| Fukushima Medical University Hospital | Fukushima-shi | Fukushima-Ken | 960-1295 | Japan | Details | |
| Kindai University Hospital | Osakasayama-shi | Osaka-Fu | 589-8511 | Japan | Details | |
| Kindai University Hospital | Ōsakasayama-shi | Osaka-Fu | 589-8511 | Japan | Details | |
| National Cancer Center Hospital | Chuo Ku | Tokyo-To | 104-0045 | Japan | Details | |
| NHO Shikoku Cancer Center | Ehime | 791-0280 | Japan | Details | ||
| NHO Kyushu Cancer Center | Fukuoka | 811-1395 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital | Hiroshima | 730-8518 | Japan | Details | ||
| NHO Hokkaido Cancer Center | Hokkaido | 003-0804 | Japan | Details | ||
| Hyōgo College of Medicine Hospital | Hyōgo | 663-8501 | Japan | Details | ||
| St. Marianna University School of Medicine Hospital | Kanagawa | 216-8511 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Kyoto University Hospital | Kyoto | 606-8507 | Japan | Details | ||
| Tohoku University Hospital | Miyagi | 980-8574 | Japan | Details | ||
| Aichi Cancer Center Hospital | Nagoya | 464-8681 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| NHO Osaka National Hospital | Osaka | 540-0006 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| Saitama Cancer Center | Saitama | 362-0806 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| Toranomon Hospital | Tokyo | 105-8470 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
| Tokyo Medical University Hospital | Tokyo | 160-0023 | Japan | Details | ||
| Chungbuk National University Hospital | Cheongju-si | Chungcheongbuk-do | 28644 | Korea, Republic of | Details | |
| Inha University Hospital | Incheon | Gyeonggi-do | 22332 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 13620 | Korea, Republic of | Details | |
| The Catholic University of Korea, St. Vincent's Hospital | Suwon-si | Gyeonggi-do | 16247 | Korea, Republic of | Details | |
| Ajou University Hospital | Suwon | Gyeonggi-do | 16499 | Korea, Republic of | Details | |
| Kyungpook National University Chilgok Hospital | Daegu | 41404 | Korea, Republic of | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University | Seoul | 03772 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea, Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| ICO Badalona - Hospital Universitari Germans Trias i Pujol | Badalona | Barcelona | 08916 | Spain | Details | |
| ICO l'Hospitalet - Hospital Duran i Reynals | L'Hospitalet De Llobregat | Barcelona | 08908 | Spain | Details | |
| Hospital de Especialidades de Jerez de la Frontera | Jerez De La Frontera | Cádiz | 11407 | Spain | Details | |
| Complejo Hospitalario Universitario A Coruña | A Coruña | La Coruña | 15006 | Spain | Details | |
| Hospital Universitario de Canarias | San Cristobal de la Laguna | Tenerife | 38320 | Spain | Details | |
| Hospital Infanta Cristina | Badajoz | 06007 | Spain | Details | ||
| Hospital Quironsalud Barcelona | Barcelona | 08023 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital del Mar | Barcelona | 8003 | Spain | Details | ||
| Hospital Universitari Arnau de Vilanova | Lleida | 25198 | Spain | Details | ||
| Hospital General Universitario Gregorio Marañon | Madrid | 28007 | Spain | Details | ||
| MD Anderson Cancer Centre | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Clinico Universitario Virgen de la Victoria | Málaga | 29010 | Spain | Details | ||
| Hospital Universitario de Salamanca | Salamanca | 37370 | Spain | Details | ||
| Hospital Universitario Virgen Macarena | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Instituto Valenciano de Oncologia IVO | Valencia | 46009 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| Acibadem Adana Hospital | Adana | 01130 | Turkey | Details | ||
| Adana Numune Training and Research Hospital | Adana | 01370 | Turkey | Details | ||
| Ankara Yildirim Beyazit Uni. Med. Fac.Ankara City Hospital | Ankara | 6800 | Turkey | Details | ||
| Akdeniz University Medical Faculty | Antalya | 07058 | Turkey | Details | ||
| Uludag University Medical Faculty | Bursa | 16059 | Turkey | Details | ||
| Istanbul University Cerrahpasa - Cerrahpasa Medical Faculty | Istanbul | 34098 | Turkey | Details | ||
| Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital | Istanbul | 34147 | Turkey | Details | ||
| Medipol University Medical Faculty | Istanbul | 34214 | Turkey | Details | ||
| Medical Park Goztepe Hospital | Istanbul | 34732 | Turkey | Details | ||
| Istanbul Medeniyet Uni Goztepe Training & Research Hospital | Istanbul | 34854 | Turkey | Details | ||
| Kartal Lutfi Kirdar Research and Training Hospital | Istanbul | 34890 | Turkey | Details | ||
| Izmir Medicalpark Hospital | İzmir | 35530 | Turkey | Details | ||
| Konya Necmettin Erbakan University Meram Faculty of Medicine | Konya | 42080 | Turkey | Details | ||
| Sakarya Traning and Research Hospital | Sakarya | 54187 | Turkey | Details | ||
| Medical Park Samsun Hastanesi | Samsun | 55200 | Turkey | Details | ||
| Namik Kemal University | Tekirdağ | 59100 | Turkey | Details | ||
| Royal Cornwall Hospital | Truro | Cornwall | TR1 3LJ | United Kingdom | Details | |
| Royal Devon and Exeter Hospital (Wonford) | Exeter | Devon | EX2 5DW | United Kingdom | Details | |
| Derriford Hospital | Plymouth | Devon | PL6 8BQ | United Kingdom | Details | |
| Aberdeen Royal Infirmary | Aberdeen | Grampian Region | AB25 2ZB | United Kingdom | Details | |
| Queen Mary University of London | London | Greater London | EC1M 6BQ | United Kingdom | Details | |
| University College London Hospitals | London | Greater London | NW1 2PG | United Kingdom | Details | |
| Sarah Cannon Research Institute UK | London | Greater London | W1G 6AD | United Kingdom | Details | |
| Western General Hospital | Edinburgh | Lothian Region | EH4 2XU | United Kingdom | Details | |
| Nottingham University Hospitals City Campus | Nottingham | Nottinghamshire | NG5 1PB | United Kingdom | Details |