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| NCT ID | NCT03711032 |
| Title | Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | DEU | CAN | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alaska Urological Institute dba Alaska Clinical Research Center ( Site 1083) | Completed | Anchorage | Alaska | 99503 | United States | Details |
| Mayo Clinic in Arizona - Phoenix ( Site 1094) | Recruiting | Phoenix | Arizona | 85054 | United States | Details |
| Arizona Urology Specialists (AUS)-Professional Park ( Site 1096) | Recruiting | Tucson | Arizona | 85704 | United States | Details |
| UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro | Active, not recruiting | Los Angeles | California | 90095 | United States | Details |
| University of California Irvine Medical Center ( Site 1061) | Recruiting | Orange | California | 92868 | United States | Details |
| Genesis Research LLC ( Site 1065) | Recruiting | Torrance | California | 90505 | United States | Details |
| Colorado Clinical Research ( Site 1100) | Recruiting | Lakewood | Colorado | 80228 | United States | Details |
| Sylvester Comprehensive Cancer Center ( Site 1056) | Recruiting | Miami | Florida | 33136 | United States | Details |
| Woodlands Medical Specialists, PA ( Site 8002) | Completed | Pensacola | Florida | 32503 | United States | Details |
| Emory School of Medicine ( Site 1076) | Recruiting | Atlanta | Georgia | 30322 | United States | Details |
| Advanced Urology ( Site 1092) | Recruiting | Roswell | Georgia | 30076 | United States | Details |
| Wichita Urology Group ( Site 1086) | Recruiting | Wichita | Kansas | 67226 | United States | Details |
| Ochsner LSU Health Shreveport - Regional Urology ( Site 1099) | Recruiting | Shreveport | Louisiana | 71106 | United States | Details |
| Henry Ford Health System ( Site 1062) | Recruiting | Detroit | Michigan | 48202 | United States | Details |
| Michigan Institute of Urology ( Site 1077) | Recruiting | Troy | Michigan | 48084 | United States | Details |
| Coastal Urology Associates ( Site 1055) | Completed | Brick | New Jersey | 08724 | United States | Details |
| Morristown Medical Center ( Site 1090) | Recruiting | Morristown | New Jersey | 07960 | United States | Details |
| Rutgers Cancer Institute of New Jersey ( Site 1059) | Active, not recruiting | New Brunswick | New Jersey | 08903 | United States | Details |
| St. Peter's Hospital Cancer Care Center ( Site 1087) | Completed | Albany | New York | 12208 | United States | Details |
| Monter Cancer Center ( Site 1080) | Recruiting | Lake Success | New York | 11042 | United States | Details |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 1074) | Recruiting | New York | New York | 10016 | United States | Details |
| Associated Medical Professionals of NY ( Site 1078) | Completed | Syracuse | New York | 13210 | United States | Details |
| Tri-State Urologic Services PSC, Inc. ( Site 1091) | Recruiting | Cincinnati | Ohio | 45212 | United States | Details |
| University Hospitals Cleveland Medical Center ( Site 1066) | Completed | Cleveland | Ohio | 44106 | United States | Details |
| Ohio State University Arthur G James Cancer Hospital & Richard J Solove Research Institute ( Site 10 | Recruiting | Columbus | Ohio | 43210 | United States | Details |
| OHSU Knight Cancer Institute ( Site 1075) | Completed | Portland | Oregon | 97210 | United States | Details |
| Oregon Urology Institute ( Site 1098) | Recruiting | Springfield | Oregon | 97477 | United States | Details |
| MidLantic Urology ( Site 1071) | Recruiting | Bala-Cynwyd | Pennsylvania | 19004 | United States | Details |
| Lancaster Urology ( Site 1079) | Recruiting | Lancaster | Pennsylvania | 17604 | United States | Details |
| University of Pennsylvania ( Site 1088) | Recruiting | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Carolina Urologic Research Center ( Site 1085) | Recruiting | Myrtle Beach | South Carolina | 29572 | United States | Details |
| Urology Associates [Nashville, TN] ( Site 1072) | Recruiting | Nashville | Tennessee | 37209 | United States | Details |
| Urology Clinics of North Texas, PLLC ( Site 1064) | Recruiting | Dallas | Texas | 75231 | United States | Details |
| University Of Texas Southwestern Medical Center ( Site 1053) | Recruiting | Dallas | Texas | 75390 | United States | Details |
| Texas Oncology-Fort Worth Cancer Center ( Site 8003) | Completed | Fort Worth | Texas | 76104 | United States | Details |
| Texas Oncology-Plano West ( Site 8001) | Completed | Plano | Texas | 75093 | United States | Details |
| University of Vermont Medical Center ( Site 1057) | Recruiting | Burlington | Vermont | 05401 | United States | Details |
| Urology of Virginia ( Site 1070) | Recruiting | Virginia Beach | Virginia | 23462 | United States | Details |
| Nothern Cancer Institute ( Site 0003) | Completed | St Leonards | New South Wales | 2065 | Australia | Details |
| Sydney Adventist Hospital ( Site 0001) | Completed | Wahroonga | New South Wales | 2076 | Australia | Details |
| Ordensklinikum Linz GmbH Elisabethinen ( Site 0052) | Recruiting | Linz | Oberosterreich | 4020 | Austria | Details |
| Univ. Klinik f. Urologie Innsbruck ( Site 0051) | Completed | Innsbruck | Tirol | 6020 | Austria | Details |
| Medizinische Universität Wien ( Site 0054) | Recruiting | Vienna | Wien | 1090 | Austria | Details |
| Universitaetsklinik Salzburg ( Site 0053) | Recruiting | Salzburg | 5020 | Austria | Details | |
| UZA University Hospital Antwerp ( Site 0105) | Recruiting | Edegem | Antwerpen | 2650 | Belgium | Details |
| CHU UCL Namur Site de Godinne ( Site 0103) | Recruiting | Yvoir | Namur | 5530 | Belgium | Details |
| O.L.V. Ziekenhuis Aalst ( Site 0106) | Recruiting | Aalst | Oost-Vlaanderen | 9300 | Belgium | Details |
| AZ Maria Middelares Gent ( Site 0102) | Recruiting | Gent | Oost-Vlaanderen | 9000 | Belgium | Details |
| UZ Gent ( Site 0101) | Recruiting | Gent | Oost-Vlaanderen | 9000 | Belgium | Details |
| Hospital São Carlos-Oncocentro Ce ( Site 1558) | Recruiting | Fortaleza | Ceara | 60135-237 | Brazil | Details |
| BP - A Beneficencia Portuguesa de São Paulo ( Site 1559) | Recruiting | Sao Paulo | 01321-001 | Brazil | Details | |
| Exdeo Clinical Research Inc. ( Site 0165) | Recruiting | Abbotsford | British Columbia | V2T 1X8 | Canada | Details |
| Silverado Resarch Inc. ( Site 0155) | Recruiting | Victoria | British Columbia | V8T 2C1 | Canada | Details |
| Horizon Health Network ( Site 0160) | Recruiting | Moncton | New Brunswick | E1C 6Z8 | Canada | Details |
| Princess Margaret Cancer Centre ( Site 0153) | Recruiting | Toronto | Ontario | M5G 2M9 | Canada | Details |
| CIUSSS du Saguenay-Lac-St-Jean ( Site 0164) | Recruiting | Chicoutimi | Quebec | G7H 5H6 | Canada | Details |
| CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0157) | Recruiting | Montreal | Quebec | H1T 2M4 | Canada | Details |
| Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0 | Recruiting | Quebec City | Quebec | G1J 1Z4 | Canada | Details |
| CHUS - Hopital Fleurimont ( Site 0152) | Recruiting | Sherbrooke | Quebec | J1H 5N4 | Canada | Details |
| Fundación Hospital San Vicente de Paúl - Rionegro - Centros Especializados o de Centros Especializad | Recruiting | Rionegro | Antioquia | 054047 | Colombia | Details |
| Oncomedica S.A.-Oncomedica S.A ( Site 1604) | Recruiting | Montería | Cordoba | 230001 | Colombia | Details |
| Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 1605) | Recruiting | Bogota | Distrito Capital De Bogota | 111321 | Colombia | Details |
| Administradora Country S.A. - Clinica del Country ( Site 1607) | Recruiting | Bogotá | Distrito Capital De Bogota | 110221 | Colombia | Details |
| Oncologos del Occidente ( Site 1608) | Recruiting | Pereira | Risaralda | 660001 | Colombia | Details |
| Hemato Oncologos SA-Oncology ( Site 1601) | Recruiting | Cali | Valle Del Cauca | 76001 | Colombia | Details |
| CIMCA ( Site 1550) | Recruiting | San José | San Jose | 10103 | Costa Rica | Details |
| Policlinico San Bosco ( Site 0600) | Recruiting | San Jose | 10103 | Costa Rica | Details | |
| Tampere University Hospital [Tampere Finland] ( Site 0201) | Recruiting | Tampere | Pirkanmaa | 33520 | Finland | Details |
| Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou ( Site 1353) | Recruiting | Rennes | Bretagne | 35033 | France | Details |
| Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand-Urology ( Site 1355) | Recruiting | Dijon | Cote-d Or | 21000 | France | Details |
| Hôpital Foch-Urology department ( Site 1351) | Recruiting | Suresnes | Hauts-de-Seine | 92150 | France | Details |
| HENRI MONDOR HOSPITAL ( Site 1357) | Recruiting | Créteil | Seine-et-Marne | 94000 | France | Details |
| Klinikum Rechts der Isar. Technischen Universitaet Muenchen ( Site 0266) | Recruiting | Munich | Bayern | 81675 | Germany | Details |
| Klinikum Weiden ( Site 0259) | Recruiting | Weiden In Der Oberpfalz | Bayern | 92637 | Germany | Details |
| Universitaetsklinikum Wuerzburg ( Site 0265) | Recruiting | Wuerzburg | Bayern | 97080 | Germany | Details |
| Krankenhaus der Barmherzigen Brüder Trier-Abteilung für Urologie und Kinderurologie ( Site 0262) | Recruiting | Trier | Rheinland-Pfalz | 54292 | Germany | Details |
| Universitaetsklinikum Jena ( Site 0252) | Recruiting | Jena | Thuringen | 07747 | Germany | Details |
| General University Hospital of Patras ( Site 0302) | Recruiting | Patra | Achaia | 265 04 | Greece | Details |
| ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0304) | Recruiting | Chaidari | Attiki | 124 62 | Greece | Details |
| Antikarkiniko Nosokomeio Thessalonikis THEAGENIO ( Site 0303) | Recruiting | Thessaloniki | Kentriki Makedonia | 54007 | Greece | Details |
| University Hospital of Larissa ( Site 0301) | Recruiting | Larissa | Thessalia | 411 10 | Greece | Details |
| Intervasc ( Site 1454) | Recruiting | Guatemala City | 01010 | Guatemala | Details | |
| INTEGRA Cancer Institute ( Site 1451) | Recruiting | Guatemala | 01010 | Guatemala | Details | |
| Grupo Medico Angeles-Grupo Medico Angeles ( Site 1453) | Recruiting | Guatemala | 01015 | Guatemala | Details | |
| Pécsi Tudományegyetem Klinikai Központ-Urológiai Klinika ( Site 1304) | Recruiting | Pécs | Baranya | 7621 | Hungary | Details |
| Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Urológiai Klinika ( Site 1303) | Recruiting | Szeged | Csongrad | 6725 | Hungary | Details |
| Semmelweis University-Urológiai Klinika ( Site 1301) | Recruiting | Budapest | 1082 | Hungary | Details | |
| Debreceni Egyetem Klinikai Kozpont ( Site 1302) | Recruiting | Debrecen | 4032 | Hungary | Details | |
| Ospedale Clinicizzato Santissima Annunziata ( Site 0361) | Recruiting | Chieti | Abruzzo | 66100 | Italy | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0353) | Recruiting | Milan | Milano | 20133 | Italy | Details |
| Ospedale Mauriziano-SCDU ONCOLOGIA MEDICA ( Site 0366) | Recruiting | Torino | Piemonte | 10128 | Italy | Details |
| Azienda Ospedaliero Universitaria Careggi ( Site 0360) | Recruiting | Firenze | Toscana | 50134 | Italy | Details |
| Osp Generale Reg di Bolzano ( Site 0355) | Recruiting | Bolzano | Trentino-Sudtirol | 39100 | Italy | Details |
| Azienda USL 8 di Arezzo-Medical Oncology ( Site 0363) | Recruiting | Arezzo | 52100 | Italy | Details | |
| Istituto Tumori Giovanni Paolo II ( Site 0357) | Completed | Bari | 70124 | Italy | Details | |
| Ospedale San Martino ( Site 0351) | Completed | Genova | 16132 | Italy | Details | |
| Ospedale San Raffaele ( Site 0362) | Recruiting | Milano | 20132 | Italy | Details | |
| Ospedale Buccheri La Ferla Fatebenefratelli ( Site 0352) | Recruiting | Palermo | 90123 | Italy | Details | |
| Policlinico Universitario A. Gemelli ( Site 0358) | Recruiting | Roma | 00168 | Italy | Details | |
| A.O.U. di Verona - Ospedale Civile Maggiore Borgo Trento ( Site 0356) | Recruiting | Verona | 37126 | Italy | Details | |
| Hirosaki University Hospital ( Site 0407) | Recruiting | Hirosaki | Aomori | 036-8563 | Japan | Details |
| Ehime University Hospital ( Site 0414) | Recruiting | Toon | Ehime | 791-0295 | Japan | Details |
| University of Tsukuba Hospital ( Site 0412) | Recruiting | Tsukuba | Ibaraki | 305-8576 | Japan | Details |
| Kitasato University Hospital ( Site 0403) | Recruiting | Sagamihara | Kanagawa | 252-0375 | Japan | Details |
| Yokosuka Kyosai Hospital ( Site 0406) | Recruiting | Yokosuka | Kanagawa | 238-8558 | Japan | Details |
| Nara Medical University Hospital ( Site 0411) | Recruiting | Kashihara | Nara | 634-8522 | Japan | Details |
| Chiba Cancer Center ( Site 0401) | Recruiting | Chiba | 260-8717 | Japan | Details | |
| Harasanshin Hospital ( Site 0410) | Recruiting | Fukuoka | 812-0033 | Japan | Details | |
| Osaka International Cancer Institute ( Site 0413) | Recruiting | Osaka | 541-8567 | Japan | Details | |
| Osaka Metropolitan University Hospital ( Site 0404) | Recruiting | Osaka | 545-8586 | Japan | Details | |
| Keio University Hospital ( Site 0405) | Recruiting | Tokyo | 160-8582 | Japan | Details | |
| Tokyo Medical and Dental University Hospital ( Site 0409) | Recruiting | Tokyo | Japan | Details | ||
| Asan Medical Center ( Site 0804) | Completed | Songpagu | Seoul | 05505 | Korea, Republic of | Details |
| Korea University Anam Hospital ( Site 0801) | Recruiting | Seoul | 02841 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 0802) | Recruiting | Seoul | 03080 | Korea, Republic of | Details | |
| Samsung Medical Center ( Site 0803) | Completed | Seoul | 06351 | Korea, Republic of | Details | |
| University Malaya Medical Centre ( Site 1180) | Completed | Kuala Lumpur | 59100 | Malaysia | Details | |
| Maastricht University Medical Centre ( Site 0453) | Recruiting | Maastricht | Limburg | 6229 HX | Netherlands | Details |
| Erasmus MC ( Site 0451) | Recruiting | Rotterdam | Zuid-Holland | 3015 EA | Netherlands | Details |
| Universitair Medisch Centrum Utrecht-Medical Oncology ( Site 0455) | Recruiting | Utrecht | 3584 CX | Netherlands | Details | |
| Akershus University Hospital ( Site 0553) | Recruiting | Lorenskog | Akershus | 1478 | Norway | Details |
| Stavanger universitetssykehus ( Site 0555) | Recruiting | Stavanger | Rogaland | 4011 | Norway | Details |
| Hospital Nacional Guillermo Almenara Irigoyen ( Site 0601) | Completed | La Victoria | Lima | 15033 | Peru | Details |
| Oncosalud ( Site 0603) | Recruiting | Lima | 15036 | Peru | Details | |
| Hospital Militar Central [Lima, Peru] ( Site 0604) | Recruiting | Lima | 15076 | Peru | Details | |
| Uniwesytecki Szpital Kliniczny we Wroclawiu ( Site 0669) | Recruiting | Wroclaw | Dolnoslaskie | 50-556 | Poland | Details |
| Nasz Lekarz Przychodnie Medyczne ( Site 0679) | Recruiting | Torun | Kujawsko-pomorskie | 87-100 | Poland | Details |
| Pratia MCM Krakow ( Site 0668) | Completed | Krakow | Malopolskie | 30-510 | Poland | Details |
| Szpital Wojewódzki im. Świętego Lukasza SP ZOZ w Tarnowie ( Site 0681) | Recruiting | Tarnow | Malopolskie | 33-100 | Poland | Details |
| Urologica Praktyka Lekarska Adam Marcheluk ( Site 0654) | Recruiting | Siedlce | Mazowieckie | 08-110 | Poland | Details |
| Luxmed Onkologia sp. z o. o. ( Site 0653) | Completed | Warszawa | Mazowieckie | 01-748 | Poland | Details |
| Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 0678) | Recruiting | Przemysl | Podkarpackie | 37-700 | Poland | Details |
| Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0671) | Recruiting | Koscierzyna | Pomorskie | 83-400 | Poland | Details |
| Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Slupsku ( Site 0655) | Recruiting | Slupsk | Pomorskie | 76-200 | Poland | Details |
| LIFTMED ( Site 0652) | Completed | Rybnik | Slaskie | 44-200 | Poland | Details |
| Clinical Research Center Sp. z o.o. ( Site 0674) | Recruiting | Poznan | Wielkopolskie | 60-848 | Poland | Details |
| 2CA Braga. Centro Clinico Academico ( Site 0705) | Recruiting | Braga | 4710-243 | Portugal | Details | |
| Inst. Portugues de Oncologia de Coimbra Francisco Gentil EPE ( Site 0704) | Completed | Coimbra | 3000-075 | Portugal | Details | |
| Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0708) | Recruiting | Lisboa | 1099-023 | Portugal | Details | |
| CHLN Hospital Santa Maria ( Site 0702) | Recruiting | Lisboa | 1649-035 | Portugal | Details | |
| Hospital CUF Descobertas ( Site 0706) | Completed | Lisboa | 1998-018 | Portugal | Details | |
| Inst. Portugues de Oncologia de Porto Francisco Gentil EPE ( Site 0701) | Recruiting | Porto | 4200-072 | Portugal | Details | |
| Advance Urology and Laparoscopic Center ( Site 0757) | Recruiting | Ponce | 00716 | Puerto Rico | Details | |
| Hospital Universitario Lucus Augusti ( Site 0852) | Recruiting | Lugo | La Coruna | 27003 | Spain | Details |
| Hospital La Fe de Valencia ( Site 0855) | Recruiting | Valencia | La Coruna | 46026 | Spain | Details |
| Hospital Universitario Quiron Madrid ( Site 0862) | Recruiting | Pozuelo de Alarcon | Madrid, Comunidad De | 28223 | Spain | Details |
| Clinica Universitaria de Navarra ( Site 0863) | Completed | Pamplona | Navarra | 31008 | Spain | Details |
| Fundacio Puigvert ( Site 0864) | Recruiting | Barcelona | 08025 | Spain | Details | |
| Hospital Universitario Gregorio Maranon ( Site 0854) | Recruiting | Madrid | 28009 | Spain | Details | |
| Clinica Universitaria Navarra - Madrid ( Site 0860) | Completed | Madrid | 28027 | Spain | Details | |
| MD Anderson Cancer Center Madrid ( Site 0859) | Recruiting | Madrid | 28033 | Spain | Details | |
| Hospital Universitario Ramon y Cajal ( Site 0857) | Recruiting | Madrid | 28034 | Spain | Details | |
| Hospital Universitario La Paz ( Site 0866) | Recruiting | Madrid | 28046 | Spain | Details | |
| Universitaetsspital Basel ( Site 1201) | Recruiting | Basel | Basel-Stadt | 4031 | Switzerland | Details |
| Hopitaux Universitaires de Geneve HUG ( Site 1204) | Recruiting | Geneve | 1205 | Switzerland | Details | |
| Universitaetsspital Zurich ( Site 1203) | Recruiting | Zurich | 8091 | Switzerland | Details | |
| China Medical University Hospital-Department of Urology ( Site 1654) | Recruiting | Taichung | 40447 | Taiwan | Details | |
| Taichung Veterans General Hospital ( Site 1653) | Recruiting | Taichung | 407 | Taiwan | Details | |
| Taipei Veterans General Hospital ( Site 1652) | Recruiting | Taipei | 11217 | Taiwan | Details | |
| Memorial Sisli Hastanesi-Medical Oncology ( Site 0965) | Recruiting | Stanbul | Istanbul | 34385 | Turkey | Details |
| Eskisehir Osmangazi Universitesi Hastanesi ( Site 0953) | Recruiting | Eskisehir | 26480 | Turkey | Details | |
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0963) | Recruiting | Istanbul | 34722 | Turkey | Details | |
| Dokuz Eylul Universitesi ( Site 0959) | Active, not recruiting | Izmir | 35340 | Turkey | Details | |
| Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 0961) | Recruiting | Konya | 42000 | Turkey | Details | |
| Raigmore Hospital ( Site 1006) | Recruiting | Inverness | Highland | IV2 3UJ | United Kingdom | Details |
| St Bartholomew s Hospital ( Site 1008) | Recruiting | London | London, City Of | EC1A 7BE | United Kingdom | Details |
| St Georges University Hospitals NHS Foundation Trust. ( Site 1005) | Recruiting | London | London, City Of | SW17 0QT | United Kingdom | Details |