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NCT ID NCT03711032
Title Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

bladder urothelial carcinoma

Therapies

BCG solution + Pembrolizumab

BCG solution

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL | AUT

Facility Status City State Zip Country Details
Alaska Urological Institute dba Alaska Clinical Research Center ( Site 1083) Completed Anchorage Alaska 99503 United States Details
Mayo Clinic in Arizona - Phoenix ( Site 1094) Recruiting Phoenix Arizona 85054 United States Details
Arizona Urology Specialists (AUS)-Professional Park ( Site 1096) Recruiting Tucson Arizona 85704 United States Details
UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro Active, not recruiting Los Angeles California 90095 United States Details
University of California Irvine Medical Center ( Site 1061) Recruiting Orange California 92868 United States Details
Genesis Research LLC ( Site 1065) Recruiting Torrance California 90505 United States Details
Colorado Clinical Research ( Site 1100) Recruiting Lakewood Colorado 80228 United States Details
Sylvester Comprehensive Cancer Center ( Site 1056) Recruiting Miami Florida 33136 United States Details
Woodlands Medical Specialists, PA ( Site 8002) Completed Pensacola Florida 32503 United States Details
Emory School of Medicine ( Site 1076) Recruiting Atlanta Georgia 30322 United States Details
Advanced Urology ( Site 1092) Recruiting Roswell Georgia 30076 United States Details
Wichita Urology Group ( Site 1086) Recruiting Wichita Kansas 67226 United States Details
Ochsner LSU Health Shreveport - Regional Urology ( Site 1099) Recruiting Shreveport Louisiana 71106 United States Details
Henry Ford Health System ( Site 1062) Recruiting Detroit Michigan 48202 United States Details
Michigan Institute of Urology ( Site 1077) Recruiting Troy Michigan 48084 United States Details
Coastal Urology Associates ( Site 1055) Completed Brick New Jersey 08724 United States Details
Morristown Medical Center ( Site 1090) Recruiting Morristown New Jersey 07960 United States Details
Rutgers Cancer Institute of New Jersey ( Site 1059) Active, not recruiting New Brunswick New Jersey 08903 United States Details
St. Peter's Hospital Cancer Care Center ( Site 1087) Completed Albany New York 12208 United States Details
Monter Cancer Center ( Site 1080) Recruiting Lake Success New York 11042 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 1074) Recruiting New York New York 10016 United States Details
Associated Medical Professionals of NY ( Site 1078) Completed Syracuse New York 13210 United States Details
Tri-State Urologic Services PSC, Inc. ( Site 1091) Recruiting Cincinnati Ohio 45212 United States Details
University Hospitals Cleveland Medical Center ( Site 1066) Completed Cleveland Ohio 44106 United States Details
Ohio State University Arthur G James Cancer Hospital & Richard J Solove Research Institute ( Site 10 Recruiting Columbus Ohio 43210 United States Details
OHSU Knight Cancer Institute ( Site 1075) Completed Portland Oregon 97210 United States Details
Oregon Urology Institute ( Site 1098) Recruiting Springfield Oregon 97477 United States Details
MidLantic Urology ( Site 1071) Recruiting Bala-Cynwyd Pennsylvania 19004 United States Details
Lancaster Urology ( Site 1079) Recruiting Lancaster Pennsylvania 17604 United States Details
University of Pennsylvania ( Site 1088) Recruiting Philadelphia Pennsylvania 19104 United States Details
Carolina Urologic Research Center ( Site 1085) Recruiting Myrtle Beach South Carolina 29572 United States Details
Urology Associates [Nashville, TN] ( Site 1072) Recruiting Nashville Tennessee 37209 United States Details
Urology Clinics of North Texas, PLLC ( Site 1064) Recruiting Dallas Texas 75231 United States Details
University Of Texas Southwestern Medical Center ( Site 1053) Recruiting Dallas Texas 75390 United States Details
Texas Oncology-Fort Worth Cancer Center ( Site 8003) Completed Fort Worth Texas 76104 United States Details
Texas Oncology-Plano West ( Site 8001) Completed Plano Texas 75093 United States Details
University of Vermont Medical Center ( Site 1057) Recruiting Burlington Vermont 05401 United States Details
Urology of Virginia ( Site 1070) Recruiting Virginia Beach Virginia 23462 United States Details
Nothern Cancer Institute ( Site 0003) Completed St Leonards New South Wales 2065 Australia Details
Sydney Adventist Hospital ( Site 0001) Completed Wahroonga New South Wales 2076 Australia Details
Ordensklinikum Linz GmbH Elisabethinen ( Site 0052) Recruiting Linz Oberosterreich 4020 Austria Details
Univ. Klinik f. Urologie Innsbruck ( Site 0051) Completed Innsbruck Tirol 6020 Austria Details
Medizinische Universität Wien ( Site 0054) Recruiting Vienna Wien 1090 Austria Details
Universitaetsklinik Salzburg ( Site 0053) Recruiting Salzburg 5020 Austria Details
UZA University Hospital Antwerp ( Site 0105) Recruiting Edegem Antwerpen 2650 Belgium Details
CHU UCL Namur Site de Godinne ( Site 0103) Recruiting Yvoir Namur 5530 Belgium Details
O.L.V. Ziekenhuis Aalst ( Site 0106) Recruiting Aalst Oost-Vlaanderen 9300 Belgium Details
AZ Maria Middelares Gent ( Site 0102) Recruiting Gent Oost-Vlaanderen 9000 Belgium Details
UZ Gent ( Site 0101) Recruiting Gent Oost-Vlaanderen 9000 Belgium Details
Hospital São Carlos-Oncocentro Ce ( Site 1558) Recruiting Fortaleza Ceara 60135-237 Brazil Details
BP - A Beneficencia Portuguesa de São Paulo ( Site 1559) Recruiting Sao Paulo 01321-001 Brazil Details
Exdeo Clinical Research Inc. ( Site 0165) Recruiting Abbotsford British Columbia V2T 1X8 Canada Details
Silverado Resarch Inc. ( Site 0155) Recruiting Victoria British Columbia V8T 2C1 Canada Details
Horizon Health Network ( Site 0160) Recruiting Moncton New Brunswick E1C 6Z8 Canada Details
Princess Margaret Cancer Centre ( Site 0153) Recruiting Toronto Ontario M5G 2M9 Canada Details
CIUSSS du Saguenay-Lac-St-Jean ( Site 0164) Recruiting Chicoutimi Quebec G7H 5H6 Canada Details
CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0157) Recruiting Montreal Quebec H1T 2M4 Canada Details
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0 Recruiting Quebec City Quebec G1J 1Z4 Canada Details
CHUS - Hopital Fleurimont ( Site 0152) Recruiting Sherbrooke Quebec J1H 5N4 Canada Details
Fundación Hospital San Vicente de Paúl - Rionegro - Centros Especializados o de Centros Especializad Recruiting Rionegro Antioquia 054047 Colombia Details
Oncomedica S.A.-Oncomedica S.A ( Site 1604) Recruiting Montería Cordoba 230001 Colombia Details
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 1605) Recruiting Bogota Distrito Capital De Bogota 111321 Colombia Details
Administradora Country S.A. - Clinica del Country ( Site 1607) Recruiting Bogotá Distrito Capital De Bogota 110221 Colombia Details
Oncologos del Occidente ( Site 1608) Recruiting Pereira Risaralda 660001 Colombia Details
Hemato Oncologos SA-Oncology ( Site 1601) Recruiting Cali Valle Del Cauca 76001 Colombia Details
CIMCA ( Site 1550) Recruiting San José San Jose 10103 Costa Rica Details
Policlinico San Bosco ( Site 0600) Recruiting San Jose 10103 Costa Rica Details
Tampere University Hospital [Tampere Finland] ( Site 0201) Recruiting Tampere Pirkanmaa 33520 Finland Details
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou ( Site 1353) Recruiting Rennes Bretagne 35033 France Details
Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand-Urology ( Site 1355) Recruiting Dijon Cote-d Or 21000 France Details
Hôpital Foch-Urology department ( Site 1351) Recruiting Suresnes Hauts-de-Seine 92150 France Details
HENRI MONDOR HOSPITAL ( Site 1357) Recruiting Créteil Seine-et-Marne 94000 France Details
Klinikum Rechts der Isar. Technischen Universitaet Muenchen ( Site 0266) Recruiting Munich Bayern 81675 Germany Details
Klinikum Weiden ( Site 0259) Recruiting Weiden In Der Oberpfalz Bayern 92637 Germany Details
Universitaetsklinikum Wuerzburg ( Site 0265) Recruiting Wuerzburg Bayern 97080 Germany Details
Krankenhaus der Barmherzigen Brüder Trier-Abteilung für Urologie und Kinderurologie ( Site 0262) Recruiting Trier Rheinland-Pfalz 54292 Germany Details
Universitaetsklinikum Jena ( Site 0252) Recruiting Jena Thuringen 07747 Germany Details
General University Hospital of Patras ( Site 0302) Recruiting Patra Achaia 265 04 Greece Details
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0304) Recruiting Chaidari Attiki 124 62 Greece Details
Antikarkiniko Nosokomeio Thessalonikis THEAGENIO ( Site 0303) Recruiting Thessaloniki Kentriki Makedonia 54007 Greece Details
University Hospital of Larissa ( Site 0301) Recruiting Larissa Thessalia 411 10 Greece Details
Intervasc ( Site 1454) Recruiting Guatemala City 01010 Guatemala Details
INTEGRA Cancer Institute ( Site 1451) Recruiting Guatemala 01010 Guatemala Details
Grupo Medico Angeles-Grupo Medico Angeles ( Site 1453) Recruiting Guatemala 01015 Guatemala Details
Pécsi Tudományegyetem Klinikai Központ-Urológiai Klinika ( Site 1304) Recruiting Pécs Baranya 7621 Hungary Details
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Urológiai Klinika ( Site 1303) Recruiting Szeged Csongrad 6725 Hungary Details
Semmelweis University-Urológiai Klinika ( Site 1301) Recruiting Budapest 1082 Hungary Details
Debreceni Egyetem Klinikai Kozpont ( Site 1302) Recruiting Debrecen 4032 Hungary Details
Ospedale Clinicizzato Santissima Annunziata ( Site 0361) Recruiting Chieti Abruzzo 66100 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0353) Recruiting Milan Milano 20133 Italy Details
Ospedale Mauriziano-SCDU ONCOLOGIA MEDICA ( Site 0366) Recruiting Torino Piemonte 10128 Italy Details
Azienda Ospedaliero Universitaria Careggi ( Site 0360) Recruiting Firenze Toscana 50134 Italy Details
Osp Generale Reg di Bolzano ( Site 0355) Recruiting Bolzano Trentino-Sudtirol 39100 Italy Details
Azienda USL 8 di Arezzo-Medical Oncology ( Site 0363) Recruiting Arezzo 52100 Italy Details
Istituto Tumori Giovanni Paolo II ( Site 0357) Completed Bari 70124 Italy Details
Ospedale San Martino ( Site 0351) Completed Genova 16132 Italy Details
Ospedale San Raffaele ( Site 0362) Recruiting Milano 20132 Italy Details
Ospedale Buccheri La Ferla Fatebenefratelli ( Site 0352) Recruiting Palermo 90123 Italy Details
Policlinico Universitario A. Gemelli ( Site 0358) Recruiting Roma 00168 Italy Details
A.O.U. di Verona - Ospedale Civile Maggiore Borgo Trento ( Site 0356) Recruiting Verona 37126 Italy Details
Hirosaki University Hospital ( Site 0407) Recruiting Hirosaki Aomori 036-8563 Japan Details
Ehime University Hospital ( Site 0414) Recruiting Toon Ehime 791-0295 Japan Details
University of Tsukuba Hospital ( Site 0412) Recruiting Tsukuba Ibaraki 305-8576 Japan Details
Kitasato University Hospital ( Site 0403) Recruiting Sagamihara Kanagawa 252-0375 Japan Details
Yokosuka Kyosai Hospital ( Site 0406) Recruiting Yokosuka Kanagawa 238-8558 Japan Details
Nara Medical University Hospital ( Site 0411) Recruiting Kashihara Nara 634-8522 Japan Details
Chiba Cancer Center ( Site 0401) Recruiting Chiba 260-8717 Japan Details
Harasanshin Hospital ( Site 0410) Recruiting Fukuoka 812-0033 Japan Details
Osaka International Cancer Institute ( Site 0413) Recruiting Osaka 541-8567 Japan Details
Osaka Metropolitan University Hospital ( Site 0404) Recruiting Osaka 545-8586 Japan Details
Keio University Hospital ( Site 0405) Recruiting Tokyo 160-8582 Japan Details
Tokyo Medical and Dental University Hospital ( Site 0409) Recruiting Tokyo Japan Details
Asan Medical Center ( Site 0804) Completed Songpagu Seoul 05505 Korea, Republic of Details
Korea University Anam Hospital ( Site 0801) Recruiting Seoul 02841 Korea, Republic of Details
Seoul National University Hospital ( Site 0802) Recruiting Seoul 03080 Korea, Republic of Details
Samsung Medical Center ( Site 0803) Completed Seoul 06351 Korea, Republic of Details
University Malaya Medical Centre ( Site 1180) Completed Kuala Lumpur 59100 Malaysia Details
Maastricht University Medical Centre ( Site 0453) Recruiting Maastricht Limburg 6229 HX Netherlands Details
Erasmus MC ( Site 0451) Recruiting Rotterdam Zuid-Holland 3015 EA Netherlands Details
Universitair Medisch Centrum Utrecht-Medical Oncology ( Site 0455) Recruiting Utrecht 3584 CX Netherlands Details
Akershus University Hospital ( Site 0553) Recruiting Lorenskog Akershus 1478 Norway Details
Stavanger universitetssykehus ( Site 0555) Recruiting Stavanger Rogaland 4011 Norway Details
Hospital Nacional Guillermo Almenara Irigoyen ( Site 0601) Completed La Victoria Lima 15033 Peru Details
Oncosalud ( Site 0603) Recruiting Lima 15036 Peru Details
Hospital Militar Central [Lima, Peru] ( Site 0604) Recruiting Lima 15076 Peru Details
Uniwesytecki Szpital Kliniczny we Wroclawiu ( Site 0669) Recruiting Wroclaw Dolnoslaskie 50-556 Poland Details
Nasz Lekarz Przychodnie Medyczne ( Site 0679) Recruiting Torun Kujawsko-pomorskie 87-100 Poland Details
Pratia MCM Krakow ( Site 0668) Completed Krakow Malopolskie 30-510 Poland Details
Szpital Wojewódzki im. Świętego Lukasza SP ZOZ w Tarnowie ( Site 0681) Recruiting Tarnow Malopolskie 33-100 Poland Details
Urologica Praktyka Lekarska Adam Marcheluk ( Site 0654) Recruiting Siedlce Mazowieckie 08-110 Poland Details
Luxmed Onkologia sp. z o. o. ( Site 0653) Completed Warszawa Mazowieckie 01-748 Poland Details
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 0678) Recruiting Przemysl Podkarpackie 37-700 Poland Details
Szpital Specjalistyczny w Koscierzynie Sp. z o.o. ( Site 0671) Recruiting Koscierzyna Pomorskie 83-400 Poland Details
Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka w Slupsku ( Site 0655) Recruiting Slupsk Pomorskie 76-200 Poland Details
LIFTMED ( Site 0652) Completed Rybnik Slaskie 44-200 Poland Details
Clinical Research Center Sp. z o.o. ( Site 0674) Recruiting Poznan Wielkopolskie 60-848 Poland Details
2CA Braga. Centro Clinico Academico ( Site 0705) Recruiting Braga 4710-243 Portugal Details
Inst. Portugues de Oncologia de Coimbra Francisco Gentil EPE ( Site 0704) Completed Coimbra 3000-075 Portugal Details
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0708) Recruiting Lisboa 1099-023 Portugal Details
CHLN Hospital Santa Maria ( Site 0702) Recruiting Lisboa 1649-035 Portugal Details
Hospital CUF Descobertas ( Site 0706) Completed Lisboa 1998-018 Portugal Details
Inst. Portugues de Oncologia de Porto Francisco Gentil EPE ( Site 0701) Recruiting Porto 4200-072 Portugal Details
Advance Urology and Laparoscopic Center ( Site 0757) Recruiting Ponce 00716 Puerto Rico Details
Hospital Universitario Lucus Augusti ( Site 0852) Recruiting Lugo La Coruna 27003 Spain Details
Hospital La Fe de Valencia ( Site 0855) Recruiting Valencia La Coruna 46026 Spain Details
Hospital Universitario Quiron Madrid ( Site 0862) Recruiting Pozuelo de Alarcon Madrid, Comunidad De 28223 Spain Details
Clinica Universitaria de Navarra ( Site 0863) Completed Pamplona Navarra 31008 Spain Details
Fundacio Puigvert ( Site 0864) Recruiting Barcelona 08025 Spain Details
Hospital Universitario Gregorio Maranon ( Site 0854) Recruiting Madrid 28009 Spain Details
Clinica Universitaria Navarra - Madrid ( Site 0860) Completed Madrid 28027 Spain Details
MD Anderson Cancer Center Madrid ( Site 0859) Recruiting Madrid 28033 Spain Details
Hospital Universitario Ramon y Cajal ( Site 0857) Recruiting Madrid 28034 Spain Details
Hospital Universitario La Paz ( Site 0866) Recruiting Madrid 28046 Spain Details
Universitaetsspital Basel ( Site 1201) Recruiting Basel Basel-Stadt 4031 Switzerland Details
Hopitaux Universitaires de Geneve HUG ( Site 1204) Recruiting Geneve 1205 Switzerland Details
Universitaetsspital Zurich ( Site 1203) Recruiting Zurich 8091 Switzerland Details
China Medical University Hospital-Department of Urology ( Site 1654) Recruiting Taichung 40447 Taiwan Details
Taichung Veterans General Hospital ( Site 1653) Recruiting Taichung 407 Taiwan Details
Taipei Veterans General Hospital ( Site 1652) Recruiting Taipei 11217 Taiwan Details
Memorial Sisli Hastanesi-Medical Oncology ( Site 0965) Recruiting Stanbul Istanbul 34385 Turkey Details
Eskisehir Osmangazi Universitesi Hastanesi ( Site 0953) Recruiting Eskisehir 26480 Turkey Details
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0963) Recruiting Istanbul 34722 Turkey Details
Dokuz Eylul Universitesi ( Site 0959) Active, not recruiting Izmir 35340 Turkey Details
Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 0961) Recruiting Konya 42000 Turkey Details
Raigmore Hospital ( Site 1006) Recruiting Inverness Highland IV2 3UJ United Kingdom Details
St Bartholomew s Hospital ( Site 1008) Recruiting London London, City Of EC1A 7BE United Kingdom Details
St Georges University Hospitals NHS Foundation Trust. ( Site 1005) Recruiting London London, City Of SW17 0QT United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field