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| NCT ID | NCT03726879 |
| Title | A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer (IMpassion050) |
| Acronym | IMpassion050 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | ESP | DEU | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| HCA Midwest Division | Kansas City | Missouri | 64132 | United States | Details | |
| New York University Medical Center PRIME; NYU Langone Medical Center | New York | New York | 10016 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| Hospital Sao Rafael - HSR | Salvador | BA | 41253-190 | Brazil | Details | |
| Hospital Araujo Jorge; Departamento de Ginecologia E Mama | Goiania | GO | 74605-070 | Brazil | Details | |
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Hospital Nossa Senhora da Conceicao | Porto Alegre | RS | 91350-200 | Brazil | Details | |
| Hospital Perola Byington | Sao Paulo | SP | 01317-000 | Brazil | Details | |
| Tom Baker Cancer Centre-Calgary | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| BCCA-Vancouver Cancer Centre | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Hopital du Saint Sacrement | Quebec City | Quebec | G1S 4L8 | Canada | Details | |
| Masarykuv onkologicky ustav | Brno | 656 53 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum | Essen | 45136 | Germany | Details | ||
| Praxis für Interdisziplinäre Onkologie und Hämatologie GbR | Freiburg | 79110 | Germany | Details | ||
| Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem | Hamburg | 20357 | Germany | Details | ||
| Sankt Elisabeth Krankenhaus; Gynaekology | Leipzig | 04277 | Germany | Details | ||
| Rotkreuzklinikum München; Frauenklinik | Muenchen | 80637 | Germany | Details | ||
| Universitätsklinikum Münster; Klinik für Frauenheilkunde und Geburtshilfe | Münster | 48149 | Germany | Details | ||
| St. Vincenz-Krankenhaus Paderborn; Haus 3 Frauenklinik | Paderborn | 33098 | Germany | Details | ||
| Universitätsfrauenklinik Ulm; Abteilung Gynäkologie | Ulm | 89075 | Germany | Details | ||
| Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica | Napoli | Campania | 80131 | Italy | Details | |
| Università degli Studi Federico II; Clinica di Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica | Aviano | Friuli-Venezia Giulia | 33081 | Italy | Details | |
| Policlinico Universitario Agostino Gemelli | Roma | Lazio | 00168 | Italy | Details | |
| ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica | Brescia | Lombardia | 25123 | Italy | Details | |
| ASST DI MONZA; Oncologia Medica | Monza | Lombardia | 20900 | Italy | Details | |
| Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia | Rozzano | Lombardia | 20089 | Italy | Details | |
| Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico | Candiolo | Piemonte | 10060 | Italy | Details | |
| IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II | Padova | Veneto | 35128 | Italy | Details | |
| National Hospital Organization Shikoku Cancer Center | Ehime | 791-0280 | Japan | Details | ||
| Fukushima Medical University Hospital | Fukushima | 960-1295 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital | Hiroshima | 730-8518 | Japan | Details | ||
| Hiroshima University Hospital | Hiroshima | 734-8551 | Japan | Details | ||
| National Hospital Organization Hokkaido Cancer Center | Hokkaido | 003-0804 | Japan | Details | ||
| Hyogo Cancer Center | Hyogo | 673-0021 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Tokai University Hospital | Kanagawa | 259-1193 | Japan | Details | ||
| Kumamoto Shinto General Hospital | Kumamoto | 862-8655 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Saitama Medical University International Medical Center | Saitama | 350-1298 | Japan | Details | ||
| Toranomon Hospital | Tokyo | 105-8470 | Japan | Details | ||
| Showa University Hospital | Tokyo | 142-8666 | Japan | Details | ||
| Gachon University Gil Medical Center | Incheon | 21565 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Samsung Medical Centre; Oncology | Seoul | 135-170 | Korea, Republic of | Details | ||
| Instytut "Centrum Zdrowia Matki Polki"; Klinika Onkologii | ?ód? | 93-338 | Poland | Details | ||
| Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; Centr.Diagn.i Lecz.Chor.Piersi | Gliwice | 44-101 | Poland | Details | ||
| Regionalny Szpital Specjalistyczny im. W. Bieganskiego; Oddzial Onkologii Klinicznej | Grudzi?dz | 86-300 | Poland | Details | ||
| Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii | Kraków | 30-688 | Poland | Details | ||
| Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad; Klinika Nowtw.Piersi i Chir.Rekonstr | Warszawa | 02-781 | Poland | Details | ||
| FSBI National Medical Research Radiological Center; A. TSYB MEDICAL RADIOLOGICAL RESEARCH CENTER | Obninsk | Kaluga | 249036 | Russian Federation | Details | |
| City Clinical Oncology Hospital | Moscow | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| SBIH "Moscow Clinical Scientific and Practical Center named after A.S. Loginov of DHM" | Moskva | Moskovskaja Oblast | 111123 | Russian Federation | Details | |
| Blokhin Cancer Research Center; Combined Treatment | Moskva | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| Petrov Research Inst. of Oncology | Sankt Petersburg | 197758 | Russian Federation | Details | ||
| Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Sant Andreu de La Barca | Barcelona | 08740 | Spain | Details | |
| Hospital Universitario Virgen de La Arrixaca; Servicio De Oncologia | El Palmar | Murcia | 30120 | Spain | Details | |
| Clinica Universitaria de Navarra; Servicio de Oncologia | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Clínic i Provincial; Servicio de Hematología y Oncología | Barcelona | 08036 | Spain | Details | ||
| Complejo Asistencial Universitario De Burgos; Servicio de Oncologia | Burgos | 09006 | Spain | Details | ||
| Hospital Clinico de Granada; Servicio de Oncologia | Granada | 18016 | Spain | Details | ||
| Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia | Jaen | 23007 | Spain | Details | ||
| Hospital Universitari Arnau de Vilanova de Lleida; Servicio de Oncologia | Lerida | 25198 | Spain | Details | ||
| Clinica Universidad de Navarra Madrid; Servicio de Oncología | Madrid | 28027 | Spain | Details | ||
| Centro Integral Oncologico Clara Campal; Servicio de Oncología | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario Virgen Macarena; Servicio de Oncologia | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| China Medical University Hospital; Surgery | Taichung | 404 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology | Taipei City | 11259 | Taiwan | Details | ||
| Mackay Memorial Hospital; Dept of Surgery | Taipei | 104 | Taiwan | Details | ||
| Chang Gung Medical Foundation - Linkou; Dept of Surgery | Taoyuan | 333 | Taiwan | Details |