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| NCT ID | NCT03839771 |
| Title | A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy (HOVON150AML) |
| Acronym | HOVON150AML |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Stichting Hemato-Oncologie voor Volwassenen Nederland |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | NLD | FRA | ESP | DEU | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| AU-Adelaide-FLINDERS | RECRUITING | Adelaide | Australia | Details | ||
| AU-Adelaide-RAH | RECRUITING | Adelaide | Australia | Details | ||
| AU-Brisbane-PAH | RECRUITING | Brisbane | Australia | Details | ||
| AU-Camperdown-RPA | RECRUITING | Camperdown | Australia | Details | ||
| AU-Canberra-CANBERRAHOSPITAL | NOT_YET_RECRUITING | Canberra | Australia | Details | ||
| AU-Douglas-TOWNSVILLE | RECRUITING | Douglas | Australia | Details | ||
| AU-Hobart TAS-RHOBART | RECRUITING | Hobart | Australia | Details | ||
| AU-Launceston TAS-LAUNCESTON | NOT_YET_RECRUITING | Launceston | Australia | Details | ||
| AU-Melbourne-ALFRED | RECRUITING | Melbourne | Australia | Details | ||
| AU-Melbourne-AUSTIN | RECRUITING | Melbourne | Australia | Details | ||
| AU-Melbourne-MONASH | RECRUITING | Melbourne | Australia | Details | ||
| AU-Melbourne-RMELBOURNE | RECRUITING | Melbourne | Australia | Details | ||
| AU-Melbourne-SVHM | RECRUITING | Melbourne | Australia | Details | ||
| AU-Perth-FSH | RECRUITING | Perth | Australia | Details | ||
| AU-Perth-RPH | NOT_YET_RECRUITING | Perth | Australia | Details | ||
| AU-Perth-SCGH | RECRUITING | Perth | Australia | Details | ||
| AU-Sydney-CONCORD | RECRUITING | Sydney | Australia | Details | ||
| AU-Sydney-RNSH | RECRUITING | Sydney | Australia | Details | ||
| AU-Sydney-SVHS | NOT_YET_RECRUITING | Sydney | Australia | Details | ||
| AU-Sydney-WSAH | RECRUITING | Sydney | Australia | Details | ||
| AU-Waratah-CALVARYMATER | NOT_YET_RECRUITING | Waratah | Australia | Details | ||
| AT-Graz-MEDUNIGRAZ | NOT_YET_RECRUITING | Graz | Austria | Details | ||
| AT-Innsbruck-IMED | NOT_YET_RECRUITING | Innsbruck | Austria | Details | ||
| AT-Linz-ORDENSKLINIKUM | NOT_YET_RECRUITING | Linz | Austria | Details | ||
| AT-Vienna-HANUSCH | NOT_YET_RECRUITING | Vienna | Austria | Details | ||
| BE-Antwerpen-ZNASTUIVENBERG | RECRUITING | Antwerpen | Belgium | Details | ||
| BE-Brugge-AZBRUGGE | RECRUITING | Brugge | Belgium | Details | ||
| BE-Brussel-BORDET | RECRUITING | Brussels | Belgium | Details | ||
| BE-Brussel-UZBRUSSEL | RECRUITING | Brussels | Belgium | Details | ||
| BE-Bruxelles-STLUC | RECRUITING | Brussels | Belgium | Details | ||
| BE-Gent-UZGENT | RECRUITING | Gent | Belgium | Details | ||
| BE-Haine-Saint-Paul-JOLIMONT | RECRUITING | Haine-Saint-Paul | Belgium | Details | ||
| BE-Hasselt-VIRGAJESSE | RECRUITING | Hasselt | Belgium | Details | ||
| BE-Leuven-UZLEUVEN | RECRUITING | Leuven | Belgium | Details | ||
| BE-Liege-CHRCITADELLE | RECRUITING | Liège | Belgium | Details | ||
| BE-Liege-CHULIEGE | RECRUITING | Liège | Belgium | Details | ||
| BE-Roeselare-AZDELTA | RECRUITING | Roeselare | Belgium | Details | ||
| BE-Yvoir-MONTGODINNE | RECRUITING | Yvoir | Belgium | Details | ||
| EE-Tartu-TARTU | RECRUITING | Tartu | Estonia | Details | ||
| FI-Helsinki-HUS | RECRUITING | Helsinki | Finland | Details | ||
| FI-Tampere-TAYS | RECRUITING | Tampere | Finland | Details | ||
| FR-Amiens-CHUAMIENS | RECRUITING | Amiens | France | Details | ||
| FR-Angers-CHUANGERS | RECRUITING | Angers | France | Details | ||
| FR-Argenteuil-CHARGENTEUIL | RECRUITING | Argenteuil | France | Details | ||
| FR-Bayonne-CHCOTEBASQUE | RECRUITING | Bayonne | France | Details | ||
| FR-Besançon Cedex-JEANMINJOZ | RECRUITING | Besançon | France | Details | ||
| FR-Bobigny-AVICENNE | RECRUITING | Bobigny | France | Details | ||
| FR-Chambery-CHMETROPOLESAVOIE | RECRUITING | Chambéry | France | Details | ||
| FR-Le Chesnay cedex-CHVERSAILLES | RECRUITING | Chesnay | France | Details | ||
| FR-Clamart-HIAPERCY | RECRUITING | Clamart | France | Details | ||
| FR-Clermont-Ferrand-ESTAING | RECRUITING | Clermont-Ferrand | France | Details | ||
| FR-Créteil cedex-CHUMONDOR | RECRUITING | Créteil | France | Details | ||
| FR-Grenoble cedex 9-CHUGRENOBLE | RECRUITING | Grenoble cedex 9 | France | Details | ||
| FR-Lens-CHLENS | RECRUITING | Lens | France | Details | ||
| FR-Lille-CHULILLE | RECRUITING | Lille | France | Details | ||
| FR-Limoges-CHULIMOGES | NOT_YET_RECRUITING | Limoges | France | Details | ||
| FR-Lyon Pierre Benite cedex-LYONSUD | RECRUITING | Lyon | France | Details | ||
| FR-Lyon-LEONBERARD | RECRUITING | Lyon | France | Details | ||
| FR-Marseille-IPC | RECRUITING | Marseille | France | Details | ||
| FR-Montpellier-STELOI | RECRUITING | Montpellier | France | Details | ||
| FR-Mulhouse-GHRMSA | RECRUITING | Mulhouse | France | Details | ||
| FR-Nantes-CHUNANTES | RECRUITING | Nantes | France | Details | ||
| FR-Nice-CAL | RECRUITING | Nice | France | Details | ||
| FR-Nice-LARCHET | RECRUITING | Nice | France | Details | ||
| FR-Orléans-CHORLEANS | RECRUITING | Orléans | France | Details | ||
| FR-Paris cedex 10-SAINTLOUIS | RECRUITING | Paris | France | Details | ||
| FR-Paris cedex 12-SAINTANTOINE | RECRUITING | Paris | France | Details | ||
| FR-Paris cedex 15-NECKER | RECRUITING | Paris | France | Details | ||
| FR-Pessac Cedex-CHUBORDEAUX | RECRUITING | Pessac | France | Details | ||
| FR-Poitiers-CHUPOITERS | RECRUITING | Poitiers | France | Details | ||
| FR-Reims-CHREIMS | RECRUITING | Reims | France | Details | ||
| FR-Rennes cedex 9-CHURENNES | RECRUITING | Rennes | France | Details | ||
| FR-Rouen cedex-BECQUEREL | RECRUITING | Rouen | France | Details | ||
| FR-Strasbourg cedex-HAUTEPIERRE | RECRUITING | Strasbourg | France | Details | ||
| FR-Toulouse-CHUTOULOUSE | RECRUITING | Toulouse | France | Details | ||
| FR-Tours cedex-BRETONNEAU | RECRUITING | Tours | France | Details | ||
| FR-Vandoeuvre Les Nancy-CHRUNANCY | RECRUITING | Vandœuvre-lès-Nancy | France | Details | ||
| FR-Villejuif-GUSTAVEROUSSY | RECRUITING | Villejuif | France | Details | ||
| DE-Bad Saarow-HELIOSBADSAAROW | RECRUITING | Bad Saarow | Germany | Details | ||
| DE-Berlin-CAMPUSBENFRANKLIN | RECRUITING | Berlin | Germany | Details | ||
| DE-Berlin-CAMPUSVIRCHOW | RECRUITING | Berlin | Germany | Details | ||
| DE-Berlin-VIVANTESNEUKOLLN | RECRUITING | Berlin | Germany | Details | ||
| DE-Berlin-VIVANTESURBAN | NOT_YET_RECRUITING | Berlin | Germany | Details | ||
| DE-Bochum-RUB | RECRUITING | Bochum | Germany | Details | ||
| DE-Bonn-UNIBONN | RECRUITING | Bonn | Germany | Details | ||
| DE-Braunschweig-KLINIKUMBRAUNSCHWEIG | RECRUITING | Braunschweig | Germany | Details | ||
| DE-Bremen-KBM | RECRUITING | Bremen | Germany | Details | ||
| DE-Dortmund-JOHODORTMUND | RECRUITING | Dortmund | Germany | Details | ||
| DE-Düsseldorf-MEDUNIDUESSELDORF | RECRUITING | Düsseldorf | Germany | Details | ||
| DE-Essen-KEM | RECRUITING | Essen | Germany | Details | ||
| DE-Esslingen-KLINIKUMESSLINGEN | RECRUITING | Esslingen | Germany | Details | ||
| DE-Flensburg-MALTESER | RECRUITING | Flensburg | Germany | Details | ||
| DE-Giessen-UKGM | NOT_YET_RECRUITING | Gießen | Germany | Details | ||
| DE-Goch-KKLE | RECRUITING | Goch | Germany | Details | ||
| DE-Hamburg-ASKLEPIOSSTGEORG | RECRUITING | Hamburg | Germany | Details | ||
| DE-Hamburg-ASKLEPIOS | RECRUITING | Hamburg | Germany | Details | ||
| DE-Hamburg-UKE | NOT_YET_RECRUITING | Hamburg | Germany | Details | ||
| DE-Hamm-EVKHAMM | RECRUITING | Hamm | Germany | Details | ||
| DE-Hanau-KLINIKUMHANAU | NOT_YET_RECRUITING | Hanau | Germany | Details | ||
| DE-Hannover-MHHANNOVER | RECRUITING | Hannover | Germany | Details | ||
| DE-Hannover-SILOAHKRH | RECRUITING | Hannover | Germany | Details | ||
| DE-Herne-MARIENHOSPITALHERNE | RECRUITING | Herne | Germany | Details | ||
| DE-Homburg-UNIKLINIKSAARLAND | RECRUITING | Homburg | Germany | Details | ||
| DE-Karlsruhe-KLINIKUMKARLSRUHE | RECRUITING | Karlsruhe | Germany | Details | ||
| DE-Lebach-CARITASKHLEBACH | NOT_YET_RECRUITING | Lebach | Germany | Details | ||
| DE-Lemgo-KLINIKUMLIPPE | RECRUITING | Lemgo | Germany | Details | ||
| DE-Ludwigshafen-KLILU | RECRUITING | Ludwigshafen | Germany | Details | ||
| DE-Luedenscheid-KLINIKUMLUEDENSCHEID | RECRUITING | Lüdenscheid | Germany | Details | ||
| DE-Magdeburg-OVGU | RECRUITING | Magdeburg | Germany | Details | ||
| DE-Mainz-KLINKUNIMAINZ | RECRUITING | Mainz | Germany | Details | ||
| DE-Mainz-UNIMEDIZINMAINZ | NOT_YET_RECRUITING | Mainz | Germany | Details | ||
| DE-Meschede-HOCHSAUERLAND | RECRUITING | Meschede | Germany | Details | ||
| DE-Minden-MUEHLENKREISKLINKEN | RECRUITING | Minden | Germany | Details | ||
| DE-München-IRZTUM | RECRUITING | München | Germany | Details | ||
| DE-München-MEDUNIMUNCHIN | NOT_YET_RECRUITING | München | Germany | Details | ||
| DE-Offenburg-ORTENAUKLINIKUM | RECRUITING | Offenburg | Germany | Details | ||
| DE-Oldenburg-KLINIKUMOLDENBURG | RECRUITING | Oldenburg | Germany | Details | ||
| DE-Passau-KLINIKUMPASSAU | RECRUITING | Passau | Germany | Details | ||
| DE-Stuttgart-DIAKSTUTTGART | RECRUITING | Stuttgart | Germany | Details | ||
| DE-Stuttgart-KLINIKUMSTUTTGART | NOT_YET_RECRUITING | Stuttgart | Germany | Details | ||
| DE-Traunstein-TSSOB | RECRUITING | Traunstein | Germany | Details | ||
| DE-Trier-MUTTERHAUS | NOT_YET_RECRUITING | Trier | Germany | Details | ||
| DE-Tübingen-MEDUNITUEBINGEN | RECRUITING | Tübingen | Germany | Details | ||
| DE-Ulm-UNIKLINKULM | RECRUITING | Ulm | Germany | Details | ||
| DE-Villingen-Schwenningen-SBKVS | RECRUITING | Villingen-Schwenningen | Germany | Details | ||
| DE-Wuppertal-HELIOSGESUNDHEIT | NOT_YET_RECRUITING | Wuppertal | Germany | Details | ||
| IE-Cork-CUH | RECRUITING | Cork | Ireland | Details | ||
| IE-Dublin 8-STJAMES | RECRUITING | Dublin | Ireland | Details | ||
| IE-Dublin 9-BEAUMONT | RECRUITING | Dublin | Ireland | Details | ||
| IE-Galway-UHGALWAY | NOT_YET_RECRUITING | Galway | Ireland | Details | ||
| LT-Vilnius-SANTA | RECRUITING | Vilnius | Lithuania | Details | ||
| LU-Luxembourg-CHL | NOT_YET_RECRUITING | Luxembourg | Luxembourg | Details | ||
| NL-Amersfoort-MEANDERMC | RECRUITING | Amersfoort | Netherlands | Details | ||
| NL-Amsterdam-AMC | RECRUITING | Amsterdam | Netherlands | Details | ||
| NL-Amsterdam-OLVG | RECRUITING | Amsterdam | Netherlands | Details | ||
| NL-Amsterdam-VUMC | RECRUITING | Amsterdam | Netherlands | Details | ||
| NL-Arnhem-RIJNSTATE | RECRUITING | Arnhem | Netherlands | Details | ||
| NL-Breda-AMPHIA | RECRUITING | Breda | Netherlands | Details | ||
| NL-Delft-RDGG | RECRUITING | Delft | Netherlands | Details | ||
| NL-Den Bosch-JBZ | RECRUITING | Den Bosch | Netherlands | Details | ||
| NL-Den Haag-HAGA | RECRUITING | Den Haag | Netherlands | Details | ||
| NL-Dordrecht-ASZ | RECRUITING | Dordrecht | Netherlands | Details | ||
| NL-Eindhoven-MAXIMAMC | RECRUITING | Eindhoven | Netherlands | Details | ||
| NL-Enschede-MST | RECRUITING | Enschede | Netherlands | Details | ||
| NL-Groningen-UMCG | RECRUITING | Groningen | Netherlands | Details | ||
| NL-Leeuwarden-MCL | RECRUITING | Leeuwarden | Netherlands | Details | ||
| NL-Leiden-LUMC | RECRUITING | Leiden | Netherlands | Details | ||
| NL-Maastricht-MUMC | RECRUITING | Maastricht | Netherlands | Details | ||
| NL-Nieuwegein-ANTONIUS | RECRUITING | Nieuwegein | Netherlands | Details | ||
| NL-Nijmegen-RADBOUDUMC | RECRUITING | Nijmegen | Netherlands | Details | ||
| NL-Rotterdam-ErasmusMC | RECRUITING | Rotterdam | Netherlands | Details | ||
| NL-Utrecht-UMCUTRECHT | RECRUITING | Utrecht | Netherlands | Details | ||
| NL-Zwolle-ISALA | RECRUITING | Zwolle | Netherlands | Details | ||
| NO-Bergen-HELSEBERGEN | RECRUITING | Bergen | Norway | Details | ||
| NO-Oslo-OSLOUH | RECRUITING | Oslo | Norway | Details | ||
| NO-Stavanger-HELSESTAVANGER | RECRUITING | Stavanger | Norway | Details | ||
| NO-Tromsø-NORTHNOORWEGEN | RECRUITING | Tromsø | Norway | Details | ||
| NO-Trondheim-STOLAV | RECRUITING | Trondheim | Norway | Details | ||
| ES-Barcelona-CLINICUB | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-GERMANTRIALS | RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-ICODURANREYNALS | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-MUTUATERRASSA | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-PARCDESALUTMAR | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-SANTPAU | RECRUITING | Barcelona | Spain | Details | ||
| ES-Barcelona-VHEBRON | NOT_YET_RECRUITING | Barcelona | Spain | Details | ||
| ES-Girona-ICSTRUETA | RECRUITING | Girona | Spain | Details | ||
| ES-Madrid-CSGREGORIOMARANON | NOT_YET_RECRUITING | Madrid | Spain | Details | ||
| ES-Palma-SSIB | RECRUITING | Palma | Spain | Details | ||
| ES-Tarragona-JOAN | NOT_YET_RECRUITING | Tarragona | Spain | Details | ||
| ES-Valencia-MALVARROSA | NOT_YET_RECRUITING | Valencia | Spain | Details | ||
| SE-Lund-SUH | RECRUITING | Lund | Sweden | Details | ||
| SE-Stockholm-KAROLINSKAHUDDINGE | RECRUITING | Stockholm | Sweden | Details | ||
| SE-Uppsala-UPPSALAUH | RECRUITING | Uppsala | Sweden | Details | ||
| CH-Basel-USB | RECRUITING | Basel | Switzerland | Details | ||
| CH-Bellinzona-IOSI | RECRUITING | Bellinzona | Switzerland | Details | ||
| CH-Bern-INSEL | RECRUITING | Bern | Switzerland | Details | ||
| CH-Fribourg-HFR | RECRUITING | Fribourg | Switzerland | Details | ||
| CH-Geneve (14)-HCUGE | RECRUITING | Geneve | Switzerland | Details | ||
| CH-Lausanne-CHUV | WITHDRAWN | Lausanne | Switzerland | Details | ||
| CH-Luzern-LUKS | RECRUITING | Luzern | Switzerland | Details | ||
| CH-St. Gallen-KSSG | RECRUITING | Saint Gallen | Switzerland | Details | ||
| CH-Zürich-USZ | RECRUITING | Zürich | Switzerland | Details |