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NCT ID NCT03898180
Title Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

urethra transitional cell carcinoma

bladder urothelial carcinoma

renal pelvis transitional cell carcinoma

ureter transitional cell carcinoma

Therapies

Lenvatinib + Pembrolizumab

Pembrolizumab

Age Groups: adult | senior
Covered Countries USA | CAN

Facility Status City State Zip Country Details
Banner MD Anderson Cancer Center ( Site 0016) Recruiting Gilbert Arizona 85234 United States Details
University of California Irvine Medical Center ( Site 0078) Recruiting Orange California 92868 United States Details
John Wayne Cancer Institute ( Site 0017) Recruiting Santa Monica California 90404 United States Details
Northwest Georgia Oncology Centers PC ( Site 0707) Recruiting Marietta Georgia 30060 United States Details
University of Chicago ( Site 0039) Recruiting Chicago Illinois 60637 United States Details
Joliet Oncology Hematology ( Site 0091) Recruiting Joliet Illinois 60436 United States Details
Quincy Medical Group ( Site 0022) Recruiting Quincy Illinois 62301 United States Details
New England Cancer Specialists ( Site 0047) Recruiting Scarborough Maine 04074 United States Details
Karmanos Cancer Institute ( Site 0712) Recruiting Detroit Michigan 48201 United States Details
Mercy Hospital Saint Louis - David C. Pratt Cancer Center ( Site 0095) Recruiting Saint Louis Missouri 63141 United States Details
Comprehensive Cancer Centers of Nevada ( Site 0005) Recruiting Las Vegas Nevada 89169 United States Details
St. Peter's Hospital Cancer Care Center ( Site 0042) Recruiting Albany New York 12208 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0002) Recruiting New York New York 10016 United States Details
Thomas Jefferson University Hospital ( Site 0051) Completed Philadelphia Pennsylvania 19107 United States Details
Medical University of South Carolina-Hollings Cancer Center ( Site 0029) Recruiting Charleston South Carolina 29425 United States Details
Baylor Scott & White Medical Center - Temple ( Site 0706) Recruiting Temple Texas 76508 United States Details
Virginia Cancer Institute ( Site 0099) Completed Richmond Virginia 23230 United States Details
Seattle Cancer Care Alliance ( Site 0003) Recruiting Seattle Washington 98109 United States Details
Cancer Care Northwest ( Site 0009) Completed Spokane Washington 99218 United States Details
Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 0577) Recruiting Berazategui Buenos Aires B1884BBF Argentina Details
Centro de Urología CDU ( Site 0590) Recruiting Buenos Aires Caba C1120AAT Argentina Details
Centro de Investigaciones Clinicas - Clinica Viedma ( Site 0585) Recruiting Viedma Rio Negro R8500ACE Argentina Details
Centro Oncológico de Rosario ( Site 0584) Recruiting Rosario Santa Fe S2000KZE Argentina Details
Instituto de Investigaciones Metabolicas ( Site 0589) Recruiting Buenos Aires C1012AAR Argentina Details
Centro Medico Dra De Salvo ( Site 0593) Recruiting Buenos Aires C1426ANZ Argentina Details
Instituto Medico Alexander Fleming ( Site 0578) Recruiting Buenos Aires C1426ANZ Argentina Details
CEMAIC ( Site 0581) Recruiting Cordoba X5008HHW Argentina Details
Centro Oncologico de Integracion Regional. COIR ( Site 0576) Recruiting Mendoza M5500AYB Argentina Details
Macquarie University ( Site 0151) Recruiting North Ryde New South Wales 2109 Australia Details
Mater Misericordiae Ltd ( Site 0158) Recruiting South Brisbane Queensland 4101 Australia Details
Monash Health ( Site 0160) Completed Clayton Victoria 3168 Australia Details
Peninsula Health Frankston Hospital ( Site 0153) Recruiting Frankston Victoria 3199 Australia Details
Austin Health-Austin Hospital ( Site 0154) Recruiting Heidelberg Victoria 3084 Australia Details
Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0101) Recruiting Hamilton Ontario L8V 5C2 Canada Details
Lakeridge Health ( Site 0103) Recruiting Oshawa Ontario L1G 2B9 Canada Details
Sunnybrook Research Institute ( Site 0106) Recruiting Toronto Ontario M4N 3M5 Canada Details
CIUSSS de l Estrie Centre Hospitalier Universitaire de Sherbrooke ( Site 0102) Recruiting Sherbrooke Quebec J1H 5H3 Canada Details
CHU de Quebec-Universite Laval-Hotel Dieu de Quebec ( Site 0104) Recruiting Quebec G1R 2J6 Canada Details
Peking University First Hospital ( Site 0726) Recruiting Beijing Beijing 100034 China Details
Peking University Third Hospital ( Site 0727) Recruiting Beijing Beijing 100089 China Details
Chongqing Cancer Hospital ( Site 0741) Recruiting Chongging Chongqing 400030 China Details
The First Affiliated Hospital of Xiamen University ( Site 0743) Recruiting Xiamen Fujian 361003 China Details
The First Affiliated Hospital of Guangzhou Medical University ( Site 0749) Recruiting Guangzhou Guangdong 510230 China Details
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University ( Site 0746) Recruiting Guangzhou Guangdong 510289 China Details
Harbin Medical University Cancer Hospital ( Site 0750) Recruiting Harbin Heilongjiang 150081 China Details
Hubei Cancer Hospital ( Site 0744) Recruiting Wuhan Hubei 430079 China Details
Hunan Cancer Hospital ( Site 0745) Recruiting Changsha Hunan 410013 China Details
Nanjing Drum Tower Hospital ( Site 0737) Recruiting Nanjing Jiangsu 210008 China Details
Fudan University Shanghai Cancer Center ( Site 0721) Recruiting Shanghai Shanghai 200032 China Details
Zhongshan Hospital Fudan University ( Site 0725) Recruiting Shanghai Shanghai 200032 China Details
The First Affiliated Hospital of Xi an Jiaotong University ( Site 0738) Recruiting Xian Shanxi 710061 China Details
Cancer Hospital Affiliated to Xinjiang Medical University ( Site 0751) Recruiting Urumqi Xinjiang 830011 China Details
Second Affiliated Hospital, Zhejiang University ( Site 0734) Recruiting Hangzhou Zhejiang 310009 China Details
Zhejiang Provincial People's Hospital ( Site 0735) Recruiting Hangzhou Zhejiang 310014 China Details
Rigshospitalet ( Site 0680) Recruiting Copenhagen Hovedstaden 2100 Denmark Details
Herlev Hospital ( Site 0681) Recruiting Herlev Hovedstaden 2730 Denmark Details
Aarhus Universitets hospital ( Site 0683) Recruiting Aarhus N Midtjylland 8200 Denmark Details
Aalborg Universitets Hospital ( Site 0684) Recruiting Aalborg Nordjylland 9000 Denmark Details
Odense Universitetshospital ( Site 0682) Recruiting Odense Syddanmark 5000 Denmark Details
Centre Leon Berard ( Site 0244) Recruiting Lyon Auvergne 69373 France Details
Institut de Cancerologie Strasbourg Europe ( Site 0232) Recruiting Strasbourg Bas-Rhin 67200 France Details
Hopital de la Timone ( Site 0246) Recruiting Marseille Bouches-du-Rhone 13005 France Details
CHIC Quimper ( Site 0245) Recruiting Quimper Finistere 29107 France Details
CHU de Bordeaux- Hopital Saint Andre ( Site 0235) Recruiting Bordeaux Gironde 33075 France Details
Clinique Pasteur ( Site 0252) Completed Tolouse Haute-Garonne 31076 France Details
Centre de Cancerologie du Grand Montpellier ( Site 0249) Recruiting Montpellier Languedoc-Roussillon 34070 France Details
Centre Rene Gauducheau ICO ( Site 0250) Recruiting Saint Herblain Loire-Atlantique 44805 France Details
Institut de Cancerologie de l Ouest Site Paul Papin ( Site 0236) Recruiting Angers Maine-et-Loire 49055 France Details
Centre D Oncologie de Gentilly ( Site 0240) Recruiting Nancy Meurthe-et-Moselle 54100 France Details
Centre Hospitalier de la Cote Basque ( Site 0239) Recruiting Bayonne Pyrenees-Atlantiques 64109 France Details
Institut Gustave Roussy ( Site 0243) Recruiting Villejuif Val-de-Marne 94805 France Details
CHD Vendee-onco-hematologie ( Site 0251) Recruiting La Roche sur Yon Vendee 85925 France Details
CHU Poitiers ( Site 0253) Recruiting Poitiers Vienne 86021 France Details
Institut Curie ( Site 0237) Recruiting Paris 75005 France Details
Klinikum der Eberhard-Karls-Universitaet Tuebingen ( Site 0271) Recruiting Tuebingen Baden-Wurttemberg 72076 Germany Details
Universitaetsklinikum Giessen und Marburg GmbH ( Site 0284) Recruiting Marburg Hessen 35032 Germany Details
Helios Kliniken Schwerin GmbH ( Site 0278) Recruiting Schwerin Mecklenburg-Vorpommern 19049 Germany Details
Universitaetsmedizin Goettingen ( Site 0281) Recruiting Gottingen Niedersachsen 37075 Germany Details
Universitaetsklinikum Essen ( Site 0274) Recruiting Essen Nordrhein-Westfalen 45147 Germany Details
Staedtisches Krankenhaus Kiel GmbH ( Site 0285) Recruiting Kiel Schleswig-Holstein 24116 Germany Details
Universitaetsklinikum Schleswig-Holstein-Campus Lubeck ( Site 0277) Recruiting Luebeck Schleswig-Holstein 23538 Germany Details
Universitaetsklinikum Hamburg-Eppendorf ( Site 0282) Recruiting Hamburg 20246 Germany Details
Bacs-Kiskun Megyei Korhaz ( Site 0510) Recruiting Kecskemet Bacs-Kiskun 6000 Hungary Details
Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Okta-Klinikai Onkológiai és Sugárterápiás Ce Recruiting Miskolc Borsod-Abauj-Zemplen 3526 Hungary Details
Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 0507) Recruiting Szolnok Jasz-Nagykun-Szolnok 5000 Hungary Details
Markusovszky Egyetemi Oktatokorhaz ( Site 0502) Recruiting Szombathely Vas 9400 Hungary Details
Bajcsy Zsilinszki Korhaz es Rendelointezet ( Site 0509) Recruiting Budapest 1106 Hungary Details
Orszagos Onkologiai Intezet ( Site 0503) Recruiting Budapest 1122 Hungary Details
Uzsoki Utcai Korhaz ( Site 0508) Recruiting Budapest 1145 Hungary Details
Somogy Megyei Kaposi Mor Oktato Korhaz ( Site 0504) Recruiting Kaposvar 7400 Hungary Details
Sheba Medical Center ( Site 0551) Completed Ramat Gan Tell Abib 5265601 Israel Details
Sourasky Medical Center ( Site 0561) Recruiting Tel Aviv Tell Abib 6423906 Israel Details
Ha Emek Medical Center ( Site 0560) Recruiting Afula 1834111 Israel Details
Assuta Ashdod Public ( Site 0562) Recruiting Ashdod 7747629 Israel Details
Rambam Medical Center ( Site 0552) Recruiting Haifa 3525408 Israel Details
Shaare Zedek Medical Center ( Site 0559) Recruiting Jerusalem 9103102 Israel Details
Hadassah Ein Kerem Medical Center ( Site 0558) Recruiting Jerusalem 9112001 Israel Details
Meir Medical Center ( Site 0554) Recruiting Kfar Saba 4428164 Israel Details
Rabin Medical Center ( Site 0553) Recruiting Petach-Tikwa 4941492 Israel Details
Assaf Harofeh Medical Center ( Site 0556) Recruiting Zerifin 70300 Israel Details
ASST Grande Ospedale Metropolitano Niguarda ( Site 0307) Recruiting Milano Lombardia 20162 Italy Details
Centro di Riferimento Oncologico CRO ( Site 0304) Recruiting Aviano Pordenone 33081 Italy Details
Istituto Tumori Giovanni Paolo II ( Site 0306) Recruiting Bari 70124 Italy Details
Policlinico S. Orsola - Malpighi (Bologna) ( Site 0302) Recruiting Bologna 40138 Italy Details
Azienda Ospedaliera per l Emergenza Cannizzaro ( Site 0305) Recruiting Catania 95126 Italy Details
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 0301) Recruiting Milano 20133 Italy Details
Azienda Ospedaliera Santa Maria ( Site 0303) Recruiting Terni 05100 Italy Details
Ospedale Borgo Roma-Oncologia ( Site 0308) Recruiting Verona 37134 Italy Details
Ehime University Hospital ( Site 0137) Recruiting Toon Aichi 791-0295 Japan Details
Hirosaki University Hospital ( Site 0123) Recruiting Hirosaki Aomori 036-8563 Japan Details
National Cancer Center Hospital East ( Site 0128) Recruiting Kashiwa Chiba 277-8577 Japan Details
Sapporo Medical University Hospital ( Site 0122) Recruiting Sapporo Hokkaido 060-8543 Japan Details
University of Tsukuba Hospital ( Site 0126) Recruiting Tsukuba Ibaraki 305-8576 Japan Details
Kitasato University Hospital ( Site 0129) Recruiting Sagamihara Kanagawa 252-0375 Japan Details
Nara Medical University Hospital ( Site 0133) Recruiting Kashihara Nara 634-8522 Japan Details
Saitama Medical University International Medical Center ( Site 0125) Recruiting Hidaka Saitama 350-1298 Japan Details
Yamaguchi University Hospital ( Site 0135) Recruiting Ube Yamaguchi 755-8505 Japan Details
Akita University Hospital ( Site 0124) Recruiting Akita 010-8543 Japan Details
Chiba Cancer Center ( Site 0127) Recruiting Chiba 260-8717 Japan Details
Nagasaki University Hospital ( Site 0136) Recruiting Nagasaki 852-8501 Japan Details
Osaka City University Hospital ( Site 0132) Recruiting Osaka 545-8586 Japan Details
Tokushima University Hospital ( Site 0134) Recruiting Tokushima 770-8503 Japan Details
Medical Hospital, Tokyo Medical And Dental University ( Site 0130) Recruiting Tokyo 113-8519 Japan Details
Chonnam National University Hwasun Hospital ( Site 0194) Recruiting Hwasun Gun Jeonranamdo 58128 Korea, Republic of Details
National Cancer Center ( Site 0196) Recruiting Goyang-si Kyonggi-do 10408 Korea, Republic of Details
Chungnam National University Hospital ( Site 0195) Recruiting Daejeon Taejon-Kwangyokshi 35015 Korea, Republic of Details
Korea University Anam Hospital ( Site 0197) Recruiting Seoul 02841 Korea, Republic of Details
Seoul National University Hospital ( Site 0191) Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital ( Site 0192) Recruiting Seoul 03722 Korea, Republic of Details
Veterans Health Service Medical Center ( Site 0198) Recruiting Seoul 05368 Korea, Republic of Details
Samsung Medical Center ( Site 0193) Recruiting Seoul 06351 Korea, Republic of Details
Ziekenhuis Rijnstate ( Site 0342) Recruiting Arnhem Gelderland 6815 AD Netherlands Details
Maastricht Universitair Medisch Centrum - MUMC ( Site 0334) Recruiting Maastricht Limburg 6229 HX Netherlands Details
VieCuri Medisch Centrum ( Site 0340) Recruiting Venlo Limburg 5912 BL Netherlands Details
Amphia Ziekenhuis Breda ( Site 0331) Recruiting Breda Noord-Brabant 4819 EV Netherlands Details
Deventer Ziekenhuis ( Site 0341) Recruiting Deventer Overijssel 7416 SE Netherlands Details
Haga Ziekenhuis ( Site 0333) Recruiting Den Haag Zuid-Holland 2545 AA Netherlands Details
Erasmus MC ( Site 0332) Recruiting Rotterdam Zuid-Holland 3015 GD Netherlands Details
St. Antonius Ziekenhuis ( Site 0335) Recruiting Utrecht 3543 AZ Netherlands Details
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego ( Site 0535) Recruiting Wroclaw Dolnoslaskie 50-556 Poland Details
Szpital Wojewodzki ( Site 1062) Recruiting Tarnow Malopolskie 33-100 Poland Details
Europejskie Centrum Zdrowia Otwock ( Site 0532) Active, not recruiting Otwock Mazowieckie 05-400 Poland Details
Urologica Praktyka Lekarska Adam Marcheluk ( Site 0543) Recruiting Siedlce Mazowieckie 08-110 Poland Details
Luxmed Onkologia sp. z o. o. ( Site 0541) Recruiting Warszawa Mazowieckie 01-748 Poland Details
Szpital Miejski im. Jana Pawła II w Bielsku-Białej ( Site 0542) Recruiting Bielsko-Biala Slaskie 43-300 Poland Details
GBUZ Leningrad Regional Clinical Oncology Dispensary ( Site 0426) Recruiting Kuzmolovskiy Settlement Leningradskaya Oblast 188663 Russian Federation Details
Russian Scientific Center of Roentgenoradiology ( Site 0424) Recruiting Moscow Moskva 117485 Russian Federation Details
Central Clinical Hospital with Polyclinic ( Site 0415) Recruiting Moscow Moskva 121359 Russian Federation Details
Medical Rehabilitation Center ( Site 0411) Recruiting Moscow Moskva 125367 Russian Federation Details
Murmansk Regional Oncology Dispensary ( Site 0420) Recruiting Murmansk Murmanskaya Oblast 183057 Russian Federation Details
Volga District Medical Center Federal Medical and Biological Agency ( Site 0413) Recruiting Nizhny Novgorod Nizhegorodskaya Oblast 603074 Russian Federation Details
Omsk Clinical Oncology Dispensary ( Site 0418) Recruiting Omsk Omskaya Oblast 644013 Russian Federation Details
Clinical Hospital Saint Luka ( Site 0421) Recruiting Saint-Petersburg Sankt-Peterburg 194044 Russian Federation Details
Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 0414) Recruiting Yaroslavl Yaroslavskaya Oblast 150054 Russian Federation Details
Institut Catala d Oncologia Hospital Germans Trias i Pujol ( Site 0351) Recruiting Badalona Barcelona 08916 Spain Details
ICO L Hospitalet ( Site 0361) Recruiting Hospitalet de Llobregat Barcelona 08908 Spain Details
Xarxa Assistencial Universitaria Manresa ( Site 0354) Recruiting Manresa Barcelona 08243 Spain Details
Hospital Teresa Herrera - Chuac ( Site 0357) Recruiting A Coruna La Coruna 15006 Spain Details
Hospital Infanta Cristina ( Site 0355) Recruiting Badajoz 06080 Spain Details
Hospital General Universitari Vall d Hebron ( Site 0358) Completed Barcelona 08035 Spain Details
Hospital La Princesa ( Site 0862) Recruiting Madrid 28006 Spain Details
Hospital Universitario Gregorio Maranon ( Site 0352) Recruiting Madrid 28009 Spain Details
Hospital Universitario HM Sanchinarro ( Site 0356) Recruiting Madrid 28050 Spain Details
Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 0216) Recruiting Kaoshiung Kaohsiung 807 Taiwan Details
Kaohsiung Chang Gung Memorial Hospital ( Site 0217) Recruiting Kaohsiung 83301 Taiwan Details
China Medical University Hospital ( Site 0213) Recruiting Taichung 40447 Taiwan Details
Taichung Veterans General Hospital ( Site 0214) Recruiting Taichung 40705 Taiwan Details
National Cheng Kung University Hospital ( Site 0215) Recruiting Tainan 70403 Taiwan Details
National Taiwan University Hospital ( Site 0211) Recruiting Taipei 100229 Taiwan Details
Taipei Veterans General Hospital ( Site 0212) Recruiting Taipei 11217 Taiwan Details
Cukurova Universitesi Tıp Fakultesi Balcalı Hastanesi ( Site 0457) Completed Adana 01330 Turkey Details
Ankara Sehir Hastanesi ( Site 0455) Recruiting Ankara 06800 Turkey Details
Antalya Memorial Hospital Department of Medical Oncology ( Site 0461) Recruiting Antalya 07020 Turkey Details
Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 0454) Recruiting Istanbul 34098 Turkey Details
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 0459) Recruiting Istanbul 34722 Turkey Details
Ege Universitesi Tulay Aktas Onkoloji Hastanesi ( Site 0462) Recruiting İzmir 35100 Turkey Details
Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 0456) Recruiting Konya 42080 Turkey Details
Sakarya Universitesi Tip Fakultesi Arastirma Hastanesi ( Site 0460) Recruiting Sakarya 54290 Turkey Details
Queens Hospital-Purple Zone ( Site 0377) Recruiting Romford Essex RM7 0AG United Kingdom Details
Lister Hospital ( Site 0376) Recruiting Stevenage Hertfordshire SG1 4AB United Kingdom Details
Kent and Canterbury Hospital ( Site 0390) Recruiting Canterbury Kent CT1 3NG United Kingdom Details
Royal Preston Hospital ( Site 0379) Recruiting Preston Lancashire PR2 9HT United Kingdom Details
Saint Bartholomew s Hospital - London ( Site 0386) Recruiting London London, City Of EC1A 7BE United Kingdom Details
University College London Hospital NHS Foundation Trust ( Site 0380) Recruiting London London, City Of NW1 2PG United Kingdom Details
Imperial Healthcare NHS Trust Charing Cross Hospital ( Site 0378) Recruiting London London, City Of W6 8RF United Kingdom Details
Nottingham University Hospital NHS Trust ( Site 0383) Recruiting Nottingham NG5 1PB United Kingdom Details
Derriford Hospital ( Site 0388) Recruiting Plymouth PL6 8DH United Kingdom Details
Weston Park Hospital ( Site 0387) Recruiting Sheffield S10 2SJ United Kingdom Details
Royal Stoke University Hospital Univ. Hosps of North Midlands NHST ( Site 0392) Recruiting Stoke-on-Trent ST4 6QG United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field