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NCT ID NCT03929666
Title A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Recruitment Recruiting
Gender both
Phase Phase II
Variant Requirements No
Sponsors Zymeworks Inc.
Indications

colorectal cancer

gastroesophageal adenocarcinoma

biliary tract cancer

Therapies

Cisplatin + Gemcitabine

Cisplatin + Fluorouracil + ZW25

Capecitabine + Oxaliplatin + ZW25

Fluorouracil + Leucovorin + Oxaliplatin + ZW25

Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin + ZW25

Age Groups: adult | senior
Covered Countries USA | CAN

Facility Status City State Zip Country Details
USC/Norris Comprehensive Cancer Center Recruiting Los Angeles California 90033 United States Details
H. Lee Moffitt Cancer Center Recruiting Tampa Florida 33612 United States Details
Cancer and Hematology Centers of Western Michigan Recruiting Kalamazoo Michigan 49007 United States Details
Nebraska Methodist Hospital Recruiting Omaha Nebraska 68114 United States Details
Memorial Sloan Kettering Cancer Center Recruiting New York New York 10065 United States Details
Fox Chase Cancer Center Recruiting Philadelphia Pennsylvania 19111 United States Details
Sarah Cannon Research Institute Recruiting Nashville Tennessee 37203 United States Details
MD Anderson Cancer Center Recruiting Houston Texas 77030 United States Details
Virginia Mason Medical Center Recruiting Seattle Washington 98101 United States Details
Princess Margaret Cancer Center Recruiting Toronto Ontario M5G 2C1 Canada Details
Centro de Estudios Clinicos SAGA SpA Recruiting Santiago 7500653 Chile Details
Icegclinic Research & Care Recruiting Santiago 8241479 Chile Details
Meditek Ltda Recruiting Santiago 8330008 Chile Details
CECIM Biocinetic Recruiting Santiago 8331143 Chile Details
Seoul National University Bundang Hospital Recruiting Seongnam-si Gyeonggi-do 13620 Korea, Republic of Details
Pusan National University Recruiting Busan 49241 Korea, Republic of Details
Korea University Anam Hospital Recruiting Seoul 02841 Korea, Republic of Details
Seoul National University Hospital Recruiting Seoul 03080 Korea, Republic of Details
Severance Hospital Recruiting Seoul 03722 Korea, Republic of Details
Asan Medical Center Recruiting Seoul 05505 Korea, Republic of Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field