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| NCT ID | NCT03976362 |
| Title | A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NZL | GBR | FRA | ESP | DEU | CAN | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alabama Oncology Bruno Cancer Center ( Site 0001) | Birmingham | Alabama | 35205 | United States | Details | |
| Disney Family Cancer Center ( Site 0005) | Burbank | California | 91505 | United States | Details | |
| Boca Raton Regional Hospital ( Site 0018) | Boca Raton | Florida | 33486 | United States | Details | |
| Mid-Florida Cancer Centers ( Site 0022) | Orange City | Florida | 32763 | United States | Details | |
| H. Lee Moffitt Cancer Center and Research Institute ( Site 0024) | Tampa | Florida | 33612 | United States | Details | |
| Columbus Regional Research Institute ( Site 0099) | Columbus | Georgia | 31904 | United States | Details | |
| Mount Sinai Hospital Medical Center ( Site 0035) | Chicago | Illinois | 60608 | United States | Details | |
| Oncology of Northshore ( Site 0036) | Rolling Meadows | Illinois | 60008 | United States | Details | |
| Methodists Hospitals/Premier Oncology Hematology Associates ( Site 0039) | Merrillville | Indiana | 46410 | United States | Details | |
| MedStar Franklin Square Medical Center ( Site 0044) | Baltimore | Maryland | 21237 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute ( Site 0046) | Detroit | Michigan | 48201 | United States | Details | |
| Hattiesburg Clinic ( Site 0051) | Hattiesburg | Mississippi | 39401 | United States | Details | |
| Frontier Oncology ( Site 0052) | Billings | Montana | 59102 | United States | Details | |
| Bozeman Health Deaconness Cancer Center ( Site 0053) | Bozeman | Montana | 59715 | United States | Details | |
| Waverly Hematology Oncology ( Site 0054) | Cary | North Carolina | 27518 | United States | Details | |
| Thompson Cancer Survival Center ( Site 2812) | Knoxville | Tennessee | 37804 | United States | Details | |
| Renovatio Clinical ( Site 0074) | The Woodlands | Texas | 77380 | United States | Details | |
| Cancer Care Northwest ( Site 0083) | Spokane Valley | Washington | 99216 | United States | Details | |
| Hospital Italiano Regional del Sur ( Site 0509) | Bahia Blanca | Buenos Aires | B8001HXM | Argentina | Details | |
| Instituto de Investigaciones Clinicas Mar del Plata ( Site 0516) | Mar del Plata | Buenos Aires | B7600FZO | Argentina | Details | |
| Hospital Britanico de Buenos Aires ( Site 0500) | Buenos Aires | Caba | C1280AEB | Argentina | Details | |
| Instituto Medico Rio Cuarto ( Site 0501) | Rio Cuarto | Cordoba | X5800AEV | Argentina | Details | |
| Sanatorio Parque ( Site 0515) | Rosario | Santa Fe | S2000DSV | Argentina | Details | |
| Centro Oncológico de Rosario ( Site 0507) | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Centro Medico San Roque ( Site 0506) | San Miguel de Tucuman | Tucuman | T4000IAK | Argentina | Details | |
| Hospital Italiano de Buenos Aires ( Site 0511) | Buenos Aires | C1199ABB | Argentina | Details | ||
| Clínica Universitaria Reina Fabiola ( Site 0505) | Cordoba | X5004FHP | Argentina | Details | ||
| Sanatorio Privado San Geronimo S.R.L ( Site 0510) | Santa Fe | S3000AOL | Argentina | Details | ||
| Liverpool Hospital ( Site 1201) | Liverpool | New South Wales | 2170 | Australia | Details | |
| Southern Medical Day Care Centre ( Site 1200) | Wollongong | New South Wales | 2500 | Australia | Details | |
| Townsville General Hospital ( Site 1202) | Townsville | Queensland | 4814 | Australia | Details | |
| Monash Cancer Centre ( Site 1205) | Clayton | Victoria | 3168 | Australia | Details | |
| Ordensklinikum Linz GmbH Elisabethinen ( Site 1307) | Linz | Oberosterreich | 4020 | Austria | Details | |
| Klinikum Wels-Grieskirchen ( Site 1304) | Wels | Oberosterreich | 4600 | Austria | Details | |
| Innsbruck LKH ( Site 1302) | Innsbruck | Tirol | 6020 | Austria | Details | |
| Social Medical Center - Otto Wagner Hospital ( Site 1301) | Vienna | Wien | 1145 | Austria | Details | |
| Krankenhaus Nord - Klinik Floridsdorf ( Site 1300) | Wien | 1210 | Austria | Details | ||
| Hospital Sao Rafael ( Site 0258) | Salvador - BA | Bahia | 41253-190 | Brazil | Details | |
| Instituto do Cancer do Ceara ( Site 0251) | Fortaleza | Ceara | 60430-230 | Brazil | Details | |
| Oncologica do Brasil ( Site 0256) | Belem | Para | 66053-000 | Brazil | Details | |
| Hospital Tacchini ( Site 0265) | Bento Goncalves | Rio Grande Do Sul | 95700-000 | Brazil | Details | |
| Irmandade da Santa Casa de Misericordia de Porto Alegre ( Site 0255) | Porto Alegre | Rio Grande Do Sul | 90050-170 | Brazil | Details | |
| Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 0252) | Itajai | Santa Catarina | 88301-220 | Brazil | Details | |
| Hospital de Base de Sao Jose de Rio Preto ( Site 0254) | Sao Jose Rio Preto | Sao Paulo | 15090-000 | Brazil | Details | |
| Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0253) | Rio de Janeiro | 20230-130 | Brazil | Details | ||
| Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0250) | Sao Paulo | 01246-000 | Brazil | Details | ||
| Hospital Paulistano - Amil Clinical Research ( Site 0263) | Sao Paulo | 01321-001 | Brazil | Details | ||
| Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0260) | Sao Paulo | 01321-001 | Brazil | Details | ||
| Nova Scotia Health Authority ( Site 0103) | Halifax | Nova Scotia | B3H 1V7 | Canada | Details | |
| Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0107) | Hamilton | Ontario | L8V5C2 | Canada | Details | |
| Kingston Health Sciences Centre ( Site 0102) | Kingston | Ontario | K7L 2V7 | Canada | Details | |
| Stronach Regional Cancer Centre ( Site 0100) | Newmarket | Ontario | L3Y 2P9 | Canada | Details | |
| CISSS de la Monteregie-Centre ( Site 0101) | Greenfield Park | Quebec | J4V 2H1 | Canada | Details | |
| Hopital Cite de la Sante de Laval ( Site 0105) | Laval | Quebec | H7M 3L9 | Canada | Details | |
| CIUSSS Ouest de l Ile - St-Mary s Hospital ( Site 0110) | Montreal | Quebec | H3T 1M5 | Canada | Details | |
| CIUSSS de la Mauricie et du Centre du Quebec ( Site 0106) | Trois-Rivieres | Quebec | G8Z 3R9 | Canada | Details | |
| Centre Hospitalier De Chauny ( Site 1411) | Chauny | Aisne | 02300 | France | Details | |
| CHU Caen ( Site 1406) | Caen | Calvados | 14033 | France | Details | |
| CHU Angers ( Site 1405) | Angers | Maine-et-Loire | 49100 | France | Details | |
| Institut De Cancerologie De Lorraine ( Site 1409) | Vandoeuvre les Nancy | Meurthe-et-Moselle | 54519 | France | Details | |
| Hopital Robert Schuman ( Site 1402) | Vantoux | Moselle | 57070 | France | Details | |
| Centre Jean Perrin ( Site 1407) | Clermont Ferrand | Puy-de-Dome | 63011 | France | Details | |
| Centre Hospitalier de Pau ( Site 1412) | Pau | Pyrenees-Atlantiques | 64000 | France | Details | |
| CHU de Rouen ( Site 1403) | Rouen | Seine-Maritime | 76000 | France | Details | |
| Hopital d'Instruction des Armees Begin ( Site 1413) | Saint-Mande | Val-de-Marne | 94163 | France | Details | |
| Studienzentrum Aschaffenburg ( Site 1575) | Aschaffenburg | Bayern | 63739 | Germany | Details | |
| Klinikum Bogenhausen Staedt. Klinikum Muenchen GmbH ( Site 1573) | Muenchen | Bayern | 81925 | Germany | Details | |
| Klinikum der LMU ( Site 1550) | Munich | Bayern | 80336 | Germany | Details | |
| Universitaetsklinikum Regensburg ( Site 1562) | Regensburg | Bayern | 93042 | Germany | Details | |
| Klinikum Wuerzburg Mitte gGmbH ( Site 1559) | Wuerzburg | Bayern | 97074 | Germany | Details | |
| Universitaetsklinikum Frankfurt ( Site 1563) | Frankfurt | Hessen | 60590 | Germany | Details | |
| Pneumologische Lehrklinik Universitaet Goettingen ( Site 1551) | Immenhausen | Hessen | 34376 | Germany | Details | |
| Universitaetsmedizin Goettingen ( Site 1557) | Goettingen | Niedersachsen | 37075 | Germany | Details | |
| Universitaetsklinikum Bonn ( Site 1574) | Bonn | Nordrhein-Westfalen | 53105 | Germany | Details | |
| Kliniken Essen Mitte ( Site 1567) | Essen | Nordrhein-Westfalen | 45136 | Germany | Details | |
| InVo-Institut fuer Versorgungsforschung in der Onkologie ( Site 1564) | Koblenz | Rheinland-Pfalz | 56068 | Germany | Details | |
| Helios Klinikum Erfurt GmbH ( Site 1552) | Erfurt | Thuringen | 99089 | Germany | Details | |
| Katholisches Marienkrankenhaus gGmbH ( Site 1572) | Hamburg | 22087 | Germany | Details | ||
| National Hospital Organization Nagoya Medical Center ( Site 0806) | Nagoya | Aichi | 460-0001 | Japan | Details | |
| Aichi Cancer Center Hospital ( Site 0803) | Nagoya | Aichi | 464-8681 | Japan | Details | |
| National Cancer Center Hospital East ( Site 0801) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Kurume University Hospital ( Site 0814) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| Kanazawa University Hospital ( Site 0811) | Kanazawa | Ishikawa | 920-8641 | Japan | Details | |
| Kanagawa Cancer Center ( Site 0807) | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Sendai Kousei Hospital ( Site 0812) | Sendai | Miyagi | 980-0873 | Japan | Details | |
| Kansai Medical University Hospital ( Site 0804) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0813) | Sakai | Osaka | 591-8555 | Japan | Details | |
| Shizuoka Cancer Center Hospital and Research Institute ( Site 0802) | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Hospital Organization Kyushu Medical Center ( Site 0805) | Fukuoka | 810-8563 | Japan | Details | ||
| Niigata Cancer Center Hospital ( Site 0808) | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital ( Site 0810) | Okayama | 700-8558 | Japan | Details | ||
| Osaka International Cancer Institute ( Site 0809) | Osaka | 541-8567 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR ( Site 0800) | Tokyo | 135-8550 | Japan | Details | ||
| Chungbuk National University Hospital ( Site 1002) | Cheongju si | Chungbuk | 28644 | Korea, Republic of | Details | |
| National Cancer Center ( Site 1006) | Goyang-si | Kyonggi-do | 10408 | Korea, Republic of | Details | |
| The Catholic University of Korea St. Vincent s Hospital ( Site 1003) | Gyeonggi-do | Kyonggi-do | 16247 | Korea, Republic of | Details | |
| Ajou University Hospital ( Site 1004) | Suwon | Kyonggi-do | 16499 | Korea, Republic of | Details | |
| Gyeongsang National University Hospital ( Site 1005) | Jinju | Kyongsangnam-do | 52727 | Korea, Republic of | Details | |
| Asan Medical Center ( Site 1007) | Songpa-gu | Seoul | 05505 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 1000) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System ( Site 1001) | Seoul | 03722 | Korea, Republic of | Details | ||
| Korea University Guro Hospital ( Site 1008) | Seoul | 08308 | Korea, Republic of | Details | ||
| Investigacion Onco Farmaceutica S de RL de CV ( Site 0300) | La Paz | Baja California Sur | 23040 | Mexico | Details | |
| Hospital Civil de Guadalajara Fray Antonio Alcalde ( Site 0334) | Guadalajara | Jalisco | 44280 | Mexico | Details | |
| Axis Heilsa S. de R.L. de C.V. ( Site 0301) | Monterrey | Nuevo Leon | 64060 | Mexico | Details | |
| CLIMERS Clinical Medical Research ( Site 0306) | Orizaba | Veracruz | 94300 | Mexico | Details | |
| Arke Estudios Clinicos ( Site 0333) | Cdmx | 06700 | Mexico | Details | ||
| FAICIC Clinical Research ( Site 0303) | Veracruz | 91900 | Mexico | Details | ||
| MidCentral DHB Palmerston North Hospital ( Site 1102) | Palmerston North | Manawatu-Wanganui | 4414 | New Zealand | Details | |
| Capital & Coast District Health Board - Wellington Hospital ( Site 1101) | Wellington | 6021 | New Zealand | Details | ||
| Samodzielny Publiczny Zespol Gruzlicy i Chorob Pluc ( Site 2417) | Olsztyn | Dolnoslaskie | 10-357 | Poland | Details | |
| Wielospecjalistyczny Szpital SPZOZ w Zgorzelcu ( Site 2404) | Zgorzelec | Dolnoslaskie | 59-900 | Poland | Details | |
| Krakowski Szpital Specjalistyczny im Jana Pawla II ( Site 2420) | Krakow | Malopolskie | 31-202 | Poland | Details | |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Szpital Rejonowy im. dr Jozefa Rostka ( Site 2402) | Raciborz | Slaskie | 47-400 | Poland | Details | |
| Przychodnia Lekarska Komed ( Site 2416) | Konin | Wielkopolskie | 62-500 | Poland | Details | |
| MED-POLONIA Sp. z o.o. ( Site 2419) | Poznan | Wielkopolskie | 60-693 | Poland | Details | |
| Cardiomed SRL Cluj-Napoca ( Site 2504) | Cluj Napoca | Cluj | 400015 | Romania | Details | |
| S.C. Radiotherapy Center Cluj S.R.L ( Site 2507) | Cluj-Napoca | Cluj | 407280 | Romania | Details | |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 2508) | Craiova | Dolj | 200347 | Romania | Details | |
| Policlinica Oncomed SRL ( Site 2505) | Timisoara | Timis | 300239 | Romania | Details | |
| S.C.Focus Lab Plus S.R.L ( Site 2502) | Bucuresti | 022548 | Romania | Details | ||
| Spitalul Clinic Judetean de Urgenta Sf Apostol Andrei ( Site 2501) | Constanta | 900591 | Romania | Details | ||
| Moscow Regional Oncological Dispensary ( Site 2028) | Balashikha | Moskovskaya Oblast | 143900 | Russian Federation | Details | |
| Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 2000) | Moscow | Moskva | 115478 | Russian Federation | Details | |
| First Moscow State Medical University n.a. I.M.Sechenov ( Site 2024) | Moscow | Moskva | 119991 | Russian Federation | Details | |
| Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2009) | Moscow | Moskva | 125284 | Russian Federation | Details | |
| FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 2006) | Moscow | Moskva | 125367 | Russian Federation | Details | |
| Nizhniy Novgorod Region Oncology Dispensary ( Site 2026) | Nizhniy Novgorod | Nizhegorodskaya Oblast | 603081 | Russian Federation | Details | |
| Budgetary Healthcare Institution of Omsk Region Clinical Oncology Dispensary-Chemotherapy #1 ( Site | Omsk | Omskaya Oblast | 644013 | Russian Federation | Details | |
| SBHI Samara Regional Clinical Oncology Dispensary ( Site 2016) | Samara | Samarskaya Oblast | 443031 | Russian Federation | Details | |
| SBHI Leningrad Regional Clinical Hospital ( Site 2002) | Saint Petersburg | Sankt-Peterburg | 194291 | Russian Federation | Details | |
| SPb Central Clinical Railway Hospital ( Site 2003) | Saint Petersburg | Sankt-Peterburg | 195271 | Russian Federation | Details | |
| National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 2004) | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details | |
| SPb SBHI City Clinical Oncological Dispensary ( Site 2001) | Saint Petersburg | Sankt-Peterburg | 198255 | Russian Federation | Details | |
| Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 2021) | Kazan | Tatarstan, Respublika | 420029 | Russian Federation | Details | |
| Hospital Duran i Reynals ( Site 1710) | Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details | |
| Complejo Hospitalario de Jaen ( Site 1713) | Jaen | La Coruna | 23007 | Spain | Details | |
| Hospital Sant Creu i Sant Pau ( Site 1711) | Barcelona | 08041 | Spain | Details | ||
| Hospital Universitario 12 de Octubre ( Site 1716) | Madrid | 28041 | Spain | Details | ||
| Complejo Hospitalario de Malaga ( Site 1714) | Malaga | 29010 | Spain | Details | ||
| Hospital Universitario Virgen Macarena ( Site 1712) | Sevilla | 41009 | Spain | Details | ||
| Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0907) | Kaohsiung | 83301 | Taiwan | Details | ||
| China Medical University Hospital ( Site 0904) | Taichung | 40447 | Taiwan | Details | ||
| National Cheng Kung University Hospital ( Site 0905) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital ( Site 0900) | Taipei | 10048 | Taiwan | Details | ||
| Mackay Memorial Hospital ( Site 0902) | Taipei | 104 | Taiwan | Details | ||
| Chang Gung Medical Foundation.Linkou Branch ( Site 0903) | Taoyuan | 333 | Taiwan | Details | ||
| Namik Kemal Universitesi Tip Fakultesi ( Site 2100) | Tekirdag | Tekirdas | 59100 | Turkey | Details | |
| Baskent Unv. Adana Uyg. ve Arast. Hastanesi ( Site 2101) | Adana | 01120 | Turkey | Details | ||
| Gazi Universitesi Tip Fakultesi ( Site 2104) | Ankara | 06500 | Turkey | Details | ||
| Ankara Sehir Hastanesi ( Site 2105) | Ankara | 06800 | Turkey | Details | ||
| Bezmialem Vakif Univ. Tıp Fakultesi Hastanesi Tibbi Onkoloji Bolumu ( Site 2107) | Istanbul | 34093 | Turkey | Details | ||
| Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 2103) | Istanbul | 34722 | Turkey | Details | ||
| Ege Universitesi Tip Fakultesi ( Site 2109) | Izmir | 35040 | Turkey | Details | ||
| Erciyes Universitesi Tip Fakultesi ( Site 2108) | Kayseri | 38039 | Turkey | Details | ||
| Ondokuz Mays Üniversitesi Tp Fakültesi Hastanesi-Oncology ( Site 2106) | Samsun | 55270 | Turkey | Details | ||
| Cherkasy Regional Oncology Dispensary ( Site 2225) | Cherkasy | Cherkaska Oblast | 18009 | Ukraine | Details | |
| City Clinical Hosp.4 of DCC ( Site 2215) | Dnipro | Dnipropetrovska Oblast | 49102 | Ukraine | Details | |
| MI Precarpathian Clinical Oncology Center ( Site 2218) | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
| Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 2226) | Kharkiv | Kharkivska Oblast | 61024 | Ukraine | Details | |
| Regional Centre of Oncology-Thoracic organs ( Site 2219) | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details | |
| PP PPC Acinus Medical and Diagnostic Centre ( Site 2223) | Kropyvnytskyi | Kirovohradska Oblast | 25006 | Ukraine | Details | |
| Medical Center Asklepion LLC ( Site 2243) | Khodosivka | Kyivska Oblast | 08173 | Ukraine | Details | |
| Kyiv City Clinical Oncology Centre ( Site 2224) | Kyiv | Kyivska Oblast | 03115 | Ukraine | Details | |
| Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 2227) | Kyiv | Kyivska Oblast | 03126 | Ukraine | Details | |
| MI Odessa Regional Oncological Centre ( Site 2222) | Odesa | Odeska Oblast | 65055 | Ukraine | Details | |
| Central City Clinical Hospital ( Site 2221) | Uzhgorod | Zakarpatska Oblast | 88000 | Ukraine | Details | |
| Medical Center Verum ( Site 2228) | Kyiv | 03039 | Ukraine | Details | ||
| Southend University Hospital NHS Foundation Trust ( Site 1913) | Westcliff-on-Sea | Essex | SS0 0RY | United Kingdom | Details | |
| Barts Health NHS Trust - St Bartholomew s Hospital ( Site 1923) | London | London, City Of | EC1M 6BQ | United Kingdom | Details | |
| Chelsea and Westminster Hospital ( Site 1901) | London | London, City Of | SW10 9NH | United Kingdom | Details | |
| Newcastle Freeman Hospital ( Site 1902) | Newcastle-upon-Tyne | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details | |
| West Suffolk Hospitals NHS Trust ( Site 1919) | Bury Saint Edmunds | Suffolk | IP33 2QZ | United Kingdom | Details | |
| Singleton Hospital ( Site 1909) | Swansea | Wales | SA2 8QA | United Kingdom | Details | |
| Colchester General Hospital ( Site 1911) | Colchester | Worcestershire | CO4 5JL | United Kingdom | Details | |
| Birmingham Heartlands Hospital ( Site 1910) | Birmingham | B9 5SS | United Kingdom | Details | ||
| Western General Hospital, Edinburgh ( Site 1924) | Edinburg | EH4 2XU | United Kingdom | Details |