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NCT ID NCT04196283
Title A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Recruitment Active, not recruiting
Gender both
Phase Phase I
Variant Requirements No
Sponsors AbbVie
Indications

hypopharynx cancer

laryngeal squamous cell carcinoma

oropharynx cancer

head and neck squamous cell carcinoma

oral squamous cell carcinoma

Therapies

ABBV-368 + IMO-2125

ABBV-368 + IMO-2125 + Nab-paclitaxel

ABBV-181 + ABBV-368 + IMO-2125 + Nab-paclitaxel

Age Groups: adult | senior
Covered Countries USA | FRA | ESP | DEU

Facility Status City State Zip Country Details
The University of Chicago Medical Center /ID# 217196 Chicago Illinois 60637-1443 United States Details
Norton Cancer Institute /ID# 216179 Louisville Kentucky 40241-2832 United States Details
Barbara Ann Karmanos Cancer In /ID# 214050 Detroit Michigan 48201 United States Details
Nebraska Methodist Hospital /ID# 215786 Omaha Nebraska 68114 United States Details
Atlantic Health System /ID# 216159 Morristown New Jersey 07960-6136 United States Details
Roswell Park Comprehensive Cancer Center /ID# 215882 Buffalo New York 14263 United States Details
Vanderbilt Ingram Cancer Center /ID# 214040 Nashville Tennessee 37232-0021 United States Details
MD Anderson Cancer Center /ID# 214041 Houston Texas 77030 United States Details
Centre Antoine Lacassagne - Nice /ID# 215706 Nice Alpes-Maritimes 06189 France Details
AP-HM - Hopital de la Timone /ID# 215657 Marseille CEDEX 05 Bouches-du-Rhone 13385 France Details
Institut Curie /ID# 215653 Paris CEDEX 05 Ile-de-France 75248 France Details
Hopital Saint-Andre /ID# 215702 Bordeaux 33075 France Details
Universitaetsklinikum Erlangen /ID# 214196 Erlangen Bayern 91054 Germany Details
Universitaetsklinikum Leipzig /ID# 214200 Leipzig Sachsen 04103 Germany Details
Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 214197 Berlin 12203 Germany Details
The Chaim Sheba Medical Center /ID# 215229 Ramat Gan Tel-Aviv 5265601 Israel Details
Rambam Health Care Campus /ID# 215231 Haifa 3109601 Israel Details
Gastroenterology Institute, Division of Medicine /ID# 215862 Jerusalem 91120 Israel Details
Antoni van Leeuwenhoek /ID# 215291 Amsterdam Noord-Holland 1066 CX Netherlands Details
Instituto Catalan de Oncologia (ICO) L'Hospitalet /ID# 221402 Hospitalet de Llobregat Barcelona 08908 Spain Details
Hospital Universitario de Fuenlabrada /ID# 214263 Fuenlabrada Madrid 28942 Spain Details
Hospital Clinic de Barcelona /ID# 214264 Barcelona 08036 Spain Details
Hospital Universitario 12 de Octubre /ID# 214198 Madrid 28041 Spain Details
Hospital Universitario HM Sanchinarro /ID# 214110 Madrid 28050 Spain Details
Hospital Universitario Virgen de la Victoria /ID# 214109 Malaga 29010 Spain Details
Hospital Clinico Universitario de Valencia /ID# 221401 Valencia 46010 Spain Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field