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NCT ID NCT04201457
Title A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration
Recruitment Recruiting
Gender both
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Pediatric Brain Tumor Consortium
Indications

high grade glioma

Therapies

Hydroxychloroquine + Trametinib

Dabrafenib + Hydroxychloroquine + Trametinib

Age Groups: child | adult
Covered Countries USA

Facility Status City State Zip Country Details
Phoenix Children's Hospital Not yet recruiting Phoenix Arizona 85016 United States Details
Children's Hospital Los Angeles Recruiting Los Angeles California 90026 United States Details
Lucile Packard Children's Hospital at Stanford University Medical Center Not yet recruiting Palo Alto California 94304 United States Details
Children's Hospital Colorado Not yet recruiting Aurora Colorado 80045 United States Details
Children's National Medical Center Recruiting Washington District of Columbia 20010-2970 United States Details
Children's Healthcare of Atlanta Recruiting Atlanta Georgia 30322 United States Details
Lurie Children's Hospital-Chicago Not yet recruiting Chicago Illinois 60614 United States Details
National Cancer Institute Pediatric Oncology Branch Not yet recruiting Bethesda Maryland 20892 United States Details
Memorial Sloan Kettering Cancer Center Recruiting New York New York 10065 United States Details
Cincinnati Children Hospital Medical Center Recruiting Cincinnati Ohio 45229 United States Details
Children's Hospital of Pittsburgh Recruiting Pittsburgh Pennsylvania 15224 United States Details
St. Jude Children Research Hospital Recruiting Memphis Tennessee 38105 United States Details
Texas Children's Cancer Center Not yet recruiting Houston Texas 77030 United States Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field