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| NCT ID | NCT04338399 |
| Title | The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC (BURAN) |
| Acronym | BURAN |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Adlai Nortye Biopharma Co., Ltd. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | United States | Details | |
| Yale University, Yale Cancer Center | New Haven | Connecticut | 06511 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Northwestern University | Chicago | Illinois | 60611 | United States | Details | |
| University of Kentucky | Lexington | Kentucky | 40536 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Washington University School of Medicine | Saint Louis | Missouri | 63130 | United States | Details | |
| Montefiore Medical Center | Bronx | New York | 10461 | United States | Details | |
| NYU Langone | New York | New York | 10016 | United States | Details | |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| University of Cincinnati Cancer Center | Cincinnati | Ohio | 45219 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Hollings Cancer Center | Charleston | South Carolina | 29425 | United States | Details | |
| West Cancer Center | Germantown | Tennessee | 38138 | United States | Details | |
| Hope Cancer Center, UT Health East Texas | Tyler | Texas | 75701 | United States | Details | |
| Fundacion Cenit para la Investigacion en Neurociencias | Buenos Aires | 1125 | Argentina | Details | ||
| Centro de Investigacion Pergamino SA - Clinica Pergamino S.A. | Buenos Aires | B2700CPM | Argentina | Details | ||
| Instituto de Investigaciones Metabólicas (IDIM) // Instituto de Investigaciones Metabólicas S.A. | Ciudad Autonoma de Buenos Aire | C1012AAR | Argentina | Details | ||
| IONC SRL- Instituto Oncológico de Córdoba | Córdoba | X5002HWE | Argentina | Details | ||
| Fundacion CORI para la Investigacion y Prevencion del Cáncer | La Rioja | F5300COE | Argentina | Details | ||
| Centro para la Atencion Integral del Paciente Oncologico - CAIPO | Tucuman | T4000GTB | Argentina | Details | ||
| Princess Alexandra Hospital | Brisbane | 4102 | Australia | Details | ||
| Universitair Ziekenhuis Gent UZ Gent | Ghent | 9000 | Belgium | Details | ||
| Universitair Ziekenhuis Brussel | Jette | 1090 | Belgium | Details | ||
| Clinique CHC MontLégia | Liege | 4000 | Belgium | Details | ||
| Clinique Saint-Pierre dOttignies CSPO | Ottignies | 1340 | Belgium | Details | ||
| CHUM | Montreal | H2X 0C2 | Canada | Details | ||
| CancerCare Manitoba | Winnipeg | R3E 0V9 | Canada | Details | ||
| Beijing Tongren Hospital | Beijing | 100176 | China | Details | ||
| The First Affiliated Hospital of Bengbu Medical College | Bengbu | 233004 | China | Details | ||
| Hunan Cancer Hospital | Changsha | 410000 | China | Details | ||
| Xiangya Hospital Central South University | Changsha | 410000 | China | Details | ||
| Sichuan Cancer Hospital | Chengdu | 610042 | China | Details | ||
| Affiliated Cancer Hospital of Chongqing University | Chongqing | 400000 | China | Details | ||
| The First Affiliated Hospital of CQMU | Chongqing | 400042 | China | Details | ||
| Sun Yat-sen University Cancer Center | Guangzhou | 510000 | China | Details | ||
| Affiliated Cancer Hospital of Guangzhou Medical University | Guangzhou | 510095 | China | Details | ||
| Zhejiang Cancer Hospital | Hangzhou | 310022 | China | Details | ||
| Anhui Provincial Cancer Hospital | Hefei | 230031 | China | Details | ||
| Shandong Provincial Tumor Hospital | Jinan | 250000 | China | Details | ||
| Yunnan Cancer Hospital | Kunming | 650000 | China | Details | ||
| Cancer Hospital affiliated to Guangxi Medical University | Naning | 530021 | China | Details | ||
| Shanghai Dongfang Hospital | Shanghai | 310115 | China | Details | ||
| Tianjin Cancer Hospital | Tianjin | 300202 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450000 | China | Details | ||
| The Fifth Affiliated Hospital of Sun Yat-sen University | Zhuhai | 519000 | China | Details | ||
| Centre hospitalier Universitaire de Bordeaux | Bordeaux | 33075 | France | Details | ||
| Centre Franois Baclesse | Caen | 14000 | France | Details | ||
| Centre Leon Berard | Lyon | 69008 | France | Details | ||
| Hopital de la Timone | Marseille | 13005 | France | Details | ||
| Institut regional du Cancer de Montpellier | Montpellier | 34298 | France | Details | ||
| LHopital prive du Confluent Nantes | Nantes | 44277 | France | Details | ||
| Clinique Hartmann | Neuilly Sur Seine | 92200 | France | Details | ||
| Hôpital St-Louis | Paris | 75010 | France | Details | ||
| Hopital La Pitie Salpetriere | Paris | 75013 | France | Details | ||
| Hopital Tenon | Paris | 75970 | France | Details | ||
| CHP Saint-Grégoire | Saint-Grégoire | 35760 | France | Details | ||
| Institut de cancerologie de Lorraine | Vandœuvre-lès-Nancy | 54500 | France | Details | ||
| Uniklinik RWTH Aachen | Aachen | 52074 | Germany | Details | ||
| Universitaetsklinikum Bonn | Bonn | 53127 | Germany | Details | ||
| University Hospital Essen | Essen | 45147 | Germany | Details | ||
| Franziskus Hospital | Georgsmarienhütte | 49124 | Germany | Details | ||
| HNO-Klinik des Universitats-Klinikums Giessen | Giessen | 35392 | Germany | Details | ||
| Universitatsmedizin Greifswald - KoR | Greifswald | 17489 | Germany | Details | ||
| Universitatsklinikum Hamburg Eppendorf | Hamburg | 20246 | Germany | Details | ||
| Marienkrankenhaus Hamburg | Hamburg | 22045 | Germany | Details | ||
| Hannover Medical School | Hannover | 30625 | Germany | Details | ||
| Universitatsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| UNIVERSITÄTSMEDIZIN Mainz III. Klinik/Poliklinik | Mainz | 55131 | Germany | Details | ||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Orszagos Onkologiai Intezet | Budapest | 1122 | Hungary | Details | ||
| University of Pecs Department of Oncotherapy | Pécs | 7624 | Hungary | Details | ||
| Tolna Megyei Balassa Janos Korhaz | Szekszárd | 7100 | Hungary | Details | ||
| Azienda Ospedaliera Universitaria S.Orsola-Malpighi | Bologna | 40138 | Italy | Details | ||
| ASST Spedali Civili Brescia | Brescia | 25123 | Italy | Details | ||
| Istituto di Candiolo IRCCS | Candiolo | 10060 | Italy | Details | ||
| IRCCS - Istituto Scientifico Romagnolo per la Cura e lo Studio dei Tumori | Cesena | Italy | Details | |||
| A.O. S. Croce e Carle | Cuneo | 12100 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Careggi - Firenze | Firenze | 50134 | Italy | Details | ||
| Azienda Ospedaliera San Paolo Polo Universitario | Milano | 20142 | Italy | Details | ||
| Istituto Nazionale dei Tumori | Milan | 20133 | Italy | Details | ||
| INT IRCCS Fondazione G.Pascale | Napoli | 80131 | Italy | Details | ||
| A.O.U. "Maggiore della Carita"- S.C.D.U Oncologiac | Novara | 28100 | Italy | Details | ||
| Azienda Ospedaliero Universitaria Policlinico "Paolo Giaccone" U.O.C. Oncologia Medica | Palermo | 90127 | Italy | Details | ||
| Azienda Ospedaliero Universitaria di Parma | Parma | 43126 | Italy | Details | ||
| IRCCS Maugeri Pavia | Pavia | 27100 | Italy | Details | ||
| IRCCS Istituto Clinico Humanitas | Rozzano | 20089 | Italy | Details | ||
| AOU San Giovanni di Dio e Ruggi D'Aragona, Università degli Studi di Salerno | Salerno | 84131 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte | Siena | 53100 | Italy | Details | ||
| ASST Valtellina e Alto Lario - UOC Oncologia Medica Ospedale di Sondrio | Sondrio | 23100 | Italy | Details | ||
| AO Card. G. Panico | Tricase | 73039 | Italy | Details | ||
| Azienda Sanitaria Universitaria Integrata di Udine | Udine | 33100 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Integrata Verona | Verona | 37126 | Italy | Details | ||
| Hyogo Cancer Center | Akashi-shi | 673-8558 | Japan | Details | ||
| National Cancer Center Hospital | Chuo Ku | 104-0045 | Japan | Details | ||
| Kyushu University Hospital | Fukuoka shi | 812-8582 | Japan | Details | ||
| Saitama Medical University International Medical Center | Hidaka | 350-1298 | Japan | Details | ||
| Kagawa University Hospital | Kita-gun | 761-0793 | Japan | Details | ||
| Kobe University Hospital | Kobe | 650-0017 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Koto-Ku | 135-8550 | Japan | Details | ||
| National Hospital Organization Shikoku Cancer Center | Matsuyama | 791-0280 | Japan | Details | ||
| Aichi Cancer Center | Nagoya | 464-8681 | Japan | Details | ||
| Kindai University Hospital | Osaka Sayama-shi | 589-8511 | Japan | Details | ||
| Hokkaido University Hospital | Sapporo | 060-8648 | Japan | Details | ||
| National University Corporation Tohoku University, Tohoku University Hospital | Sendai | 980-8574 | Japan | Details | ||
| Showa University Hospital | Shinagawa-Ku | 142-8666 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| Kosin University Gospel Hospital | Busan | 49267 | Korea, Republic of | Details | ||
| Gachon University Gil Medical Center | Incheon | 21565 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 13620 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 2841 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 5505 | Korea, Republic of | Details | ||
| The Catholic University of Korea Seoul ST. Mary's Hospital | Seoul | 6591 | Korea, Republic of | Details | ||
| Korea University Guro Hospital | Seoul | 8308 | Korea, Republic of | Details | ||
| Ajou University Hospital | Suwon-si | 16499 | Korea, Republic of | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie | Gliwice | 44-102 | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie | Warszawa | 02-781 | Poland | Details | ||
| Fundacion Oncologico de Galicia Jos Antonio Quiroga y Pieyro | A Coruña | 15009 | Spain | Details | ||
| Institut Catala d Oncologia Badalona | Badalona | 08916 | Spain | Details | ||
| Hospital de la Santa Creu i Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Vall dHebron Institute of Oncology (VHIO) | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario de Burgos | Burgos | 09006 | Spain | Details | ||
| Hospital Reina Sofia | Córdoba | 14004 | Spain | Details | ||
| Hospital Duran i Reynals - Institut Catala dOncologia ICO | Hospitalet de Llobregat | 08908 | Spain | Details | ||
| Complejo Hospitalario de Jaen | Jaén | 23007 | Spain | Details | ||
| Hospital Universitario Severo Ochoa | Leganés | 28911 | Spain | Details | ||
| Hospital Universitario Lucus Augusti | Lugo | 27003 | Spain | Details | ||
| Clinica Universidad de Navarra | Madrid | 28027 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| Hospital Clinico Universitario Virgen de la Arrixaca | Madrid | 30120 | Spain | Details | ||
| Hospital General Universitario Gregorio Maran | Madrid | Spain | Details | |||
| Hospital Puerta de Hierro- Majadahonda | Majadahonda | 28220 | Spain | Details | ||
| Hospital Regional de Malaga | Málaga | 29010 | Spain | Details | ||
| Hospital de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hospital Universitario Marques de Valdecilla | Santander | 39008 | Spain | Details | ||
| Hospital Universitario Santiago de Compostela | Santiago De Compostela | 15706 | Spain | Details | ||
| Valme Hospital Medical Oncology Department | Sevilla | 41014 | Spain | Details | ||
| Instituto Valenciano de Oncologia | Valencia | 46009 | Spain | Details | ||
| Hospital Clinico Universitario Valencia - INCLIVA | Valencia | 46010 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| Changhua Christian Hospital | Changhua | 500 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-KaohSiung | Kaohsiung | 833 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 704017 | Taiwan | Details | ||
| Chi Mei Medical Center Liouying | Tainan | 73657 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 11217 | Taiwan | Details | ||
| Chang Gung Memorial Hospital-LinKou | Taoyuan | 33342 | Taiwan | Details | ||
| Edinburgh Cancer Center | Edinburgh | EH4 2XU | United Kingdom | Details | ||
| Beatson Oncology Centre | Glasgow | G12 0YN | United Kingdom | Details | ||
| University College London Hospitals | London | NW1 2BU | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | London | SW3 6JJ | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust - Sutton | Sutton | SM2 5PT | United Kingdom | Details |