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| NCT ID | NCT04556773 |
| Title | A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer (DB-08) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies |
Fulvestrant + Trastuzumab deruxtecan Durvalumab + Paclitaxel + Trastuzumab deruxtecan Capivasertib + Trastuzumab deruxtecan |
| Age Groups: | adult | senior |
| Covered Countries | USA | FRA | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | Not yet recruiting | Iowa City | Iowa | 52242 | United States | Details |
| Research Site | Recruiting | Minneapolis | Minnesota | 55426 | United States | Details |
| Research Site | Recruiting | Saint Paul | Minnesota | 55101 | United States | Details |
| Research Site | Recruiting | Basking Ridge | New Jersey | 07920 | United States | Details |
| Research Site | Recruiting | Middletown | New Jersey | 07748 | United States | Details |
| Research Site | Recruiting | Montvale | New Jersey | 07645 | United States | Details |
| Research Site | Recruiting | Ridgewood | New Jersey | 07450 | United States | Details |
| Research Site | Recruiting | Commack | New York | 11725 | United States | Details |
| Research Site | Recruiting | Harrison | New York | 10604 | United States | Details |
| Research Site | Withdrawn | Long Island City | New York | 11101 | United States | Details |
| Research Site | Recruiting | New York | New York | 10011 | United States | Details |
| Research Site | Recruiting | New York | New York | 10019 | United States | Details |
| Research Site | Recruiting | New York | New York | 10029 | United States | Details |
| Research Site | Recruiting | New York | New York | 10065 | United States | Details |
| Research Site | Recruiting | Uniondale | New York | 11553 | United States | Details |
| Research Site | Recruiting | Chapel Hill | North Carolina | 27514 | United States | Details |
| Research Site | Withdrawn | Portland | Oregon | 97239 | United States | Details |
| Research Site | Recruiting | Chattanooga | Tennessee | 37404 | United States | Details |
| Research Site | Recruiting | Germantown | Tennessee | 38138 | United States | Details |
| Research Site | Recruiting | Fort Worth | Texas | 76104 | United States | Details |
| Research Site | Withdrawn | Fairfax | Virginia | 22031 | United States | Details |
| Research Site | Recruiting | East Melbourne | 3002 | Australia | Details | |
| Research Site | Withdrawn | Melbourne | 3004 | Australia | Details | |
| Research Site | Recruiting | Westmead | 2145 | Australia | Details | |
| Research Site | Withdrawn | Anderlecht | 1070 | Belgium | Details | |
| Research Site | Not yet recruiting | Antwerpen | 2020 | Belgium | Details | |
| Research Site | Recruiting | Edegem | 2650 | Belgium | Details | |
| Research Site | Recruiting | Leuven | 3000 | Belgium | Details | |
| Research Site | Recruiting | Ottignies | 1340 | Belgium | Details | |
| Research Site | Not yet recruiting | Brasília | 70200-730 | Brazil | Details | |
| Research Site | Not yet recruiting | Goiania | 74605-070 | Brazil | Details | |
| Research Site | Not yet recruiting | Porto Alegre | 90035-003 | Brazil | Details | |
| Research Site | Recruiting | Porto Alegre | 90110-270 | Brazil | Details | |
| Research Site | Withdrawn | Rio de Janeiro | 22250-905 | Brazil | Details | |
| Research Site | Not yet recruiting | Sao Paulo | 01317-001 | Brazil | Details | |
| Research Site | Recruiting | Sao Paulo | 04543-000 | Brazil | Details | |
| Research Site | Not yet recruiting | São Paulo | 03102-002 | Brazil | Details | |
| Research Site | Not yet recruiting | São Paulo | 04538-132 | Brazil | Details | |
| Research Site | Recruiting | Kelowna | British Columbia | V1Y 5L3 | Canada | Details |
| Research Site | Recruiting | Quebec | G1J 1Z4 | Canada | Details | |
| Research Site | Recruiting | Villejuif Cedex | 94805 | France | Details | |
| Research Site | Recruiting | Seoul | 03080 | Korea, Republic of | Details | |
| Research Site | Recruiting | Seoul | 03722 | Korea, Republic of | Details | |
| Research Site | Recruiting | Seoul | 05505 | Korea, Republic of | Details | |
| Research Site | Recruiting | Seoul | 06351 | Korea, Republic of | Details | |
| Research Site | Not yet recruiting | Culiacán | 80230 | Mexico | Details | |
| Research Site | Not yet recruiting | La Paz | 23040 | Mexico | Details | |
| Research Site | Not yet recruiting | Merida | 97000 | Mexico | Details | |
| Research Site | Not yet recruiting | Monterrey | 64710 | Mexico | Details | |
| Research Site | Withdrawn | Moscow | 105229 | Russian Federation | Details | |
| Research Site | Suspended | Moscow | 115478 | Russian Federation | Details | |
| Research Site | Suspended | Moscow | 143442 | Russian Federation | Details | |
| Research Site | Withdrawn | Saint Petersburg | 194017 | Russian Federation | Details | |
| Research Site | Withdrawn | Saint Petersburg | 195271 | Russian Federation | Details | |
| Research Site | Suspended | Saint Petersburg | 199226 | Russian Federation | Details | |
| Research Site | Suspended | Saint-Petersburg | 197758 | Russian Federation | Details | |
| Research Site | Recruiting | Kaohsiung | 82445 | Taiwan | Details | |
| Research Site | Recruiting | Taichung | 40443 | Taiwan | Details | |
| Research Site | Recruiting | Taipei City | 114 | Taiwan | Details | |
| Research Site | Recruiting | Taipei | 100 | Taiwan | Details | |
| Research Site | Recruiting | Taipei | 11217 | Taiwan | Details | |
| Research Site | Recruiting | Taipei | 235 | Taiwan | Details | |
| Research Site | Recruiting | Taoyuan | 333 | Taiwan | Details |