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NCT ID NCT04556773
Title A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer (DB-08)
Recruitment Recruiting
Gender both
Phase Phase I
Variant Requirements No
Sponsors AstraZeneca
Indications

Her2-receptor negative breast cancer

Therapies

Fulvestrant + Trastuzumab deruxtecan

Durvalumab + Paclitaxel + Trastuzumab deruxtecan

Capivasertib + Trastuzumab deruxtecan

Capecitabine + Trastuzumab deruxtecan

Anastrozole + Trastuzumab deruxtecan

Age Groups: adult | senior
Covered Countries USA | FRA | CAN | BEL

Facility Status City State Zip Country Details
Research Site Not yet recruiting Iowa City Iowa 52242 United States Details
Research Site Recruiting Minneapolis Minnesota 55426 United States Details
Research Site Recruiting Saint Paul Minnesota 55101 United States Details
Research Site Recruiting Basking Ridge New Jersey 07920 United States Details
Research Site Recruiting Middletown New Jersey 07748 United States Details
Research Site Recruiting Montvale New Jersey 07645 United States Details
Research Site Recruiting Ridgewood New Jersey 07450 United States Details
Research Site Recruiting Commack New York 11725 United States Details
Research Site Recruiting Harrison New York 10604 United States Details
Research Site Withdrawn Long Island City New York 11101 United States Details
Research Site Recruiting New York New York 10011 United States Details
Research Site Recruiting New York New York 10019 United States Details
Research Site Recruiting New York New York 10029 United States Details
Research Site Recruiting New York New York 10065 United States Details
Research Site Recruiting Uniondale New York 11553 United States Details
Research Site Recruiting Chapel Hill North Carolina 27514 United States Details
Research Site Withdrawn Portland Oregon 97239 United States Details
Research Site Recruiting Chattanooga Tennessee 37404 United States Details
Research Site Recruiting Germantown Tennessee 38138 United States Details
Research Site Recruiting Fort Worth Texas 76104 United States Details
Research Site Withdrawn Fairfax Virginia 22031 United States Details
Research Site Recruiting East Melbourne 3002 Australia Details
Research Site Withdrawn Melbourne 3004 Australia Details
Research Site Recruiting Westmead 2145 Australia Details
Research Site Withdrawn Anderlecht 1070 Belgium Details
Research Site Not yet recruiting Antwerpen 2020 Belgium Details
Research Site Recruiting Edegem 2650 Belgium Details
Research Site Recruiting Leuven 3000 Belgium Details
Research Site Recruiting Ottignies 1340 Belgium Details
Research Site Not yet recruiting Brasília 70200-730 Brazil Details
Research Site Not yet recruiting Goiania 74605-070 Brazil Details
Research Site Not yet recruiting Porto Alegre 90035-003 Brazil Details
Research Site Recruiting Porto Alegre 90110-270 Brazil Details
Research Site Withdrawn Rio de Janeiro 22250-905 Brazil Details
Research Site Not yet recruiting Sao Paulo 01317-001 Brazil Details
Research Site Recruiting Sao Paulo 04543-000 Brazil Details
Research Site Not yet recruiting São Paulo 03102-002 Brazil Details
Research Site Not yet recruiting São Paulo 04538-132 Brazil Details
Research Site Recruiting Kelowna British Columbia V1Y 5L3 Canada Details
Research Site Recruiting Quebec G1J 1Z4 Canada Details
Research Site Recruiting Villejuif Cedex 94805 France Details
Research Site Recruiting Seoul 03080 Korea, Republic of Details
Research Site Recruiting Seoul 03722 Korea, Republic of Details
Research Site Recruiting Seoul 05505 Korea, Republic of Details
Research Site Recruiting Seoul 06351 Korea, Republic of Details
Research Site Not yet recruiting Culiacán 80230 Mexico Details
Research Site Not yet recruiting La Paz 23040 Mexico Details
Research Site Not yet recruiting Merida 97000 Mexico Details
Research Site Not yet recruiting Monterrey 64710 Mexico Details
Research Site Withdrawn Moscow 105229 Russian Federation Details
Research Site Suspended Moscow 115478 Russian Federation Details
Research Site Suspended Moscow 143442 Russian Federation Details
Research Site Withdrawn Saint Petersburg 194017 Russian Federation Details
Research Site Withdrawn Saint Petersburg 195271 Russian Federation Details
Research Site Suspended Saint Petersburg 199226 Russian Federation Details
Research Site Suspended Saint-Petersburg 197758 Russian Federation Details
Research Site Recruiting Kaohsiung 82445 Taiwan Details
Research Site Recruiting Taichung 40443 Taiwan Details
Research Site Recruiting Taipei City 114 Taiwan Details
Research Site Recruiting Taipei 100 Taiwan Details
Research Site Recruiting Taipei 11217 Taiwan Details
Research Site Recruiting Taipei 235 Taiwan Details
Research Site Recruiting Taoyuan 333 Taiwan Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field