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NCT ID NCT04685135
Title Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-12)
Acronym KRYSTAL-12
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Mirati Therapeutics Inc.
Age Groups: adult | senior
Covered Countries USA | NLD | ITA | GBR | FRA | ESP | DEU | BEL | AUT | AUS

Facility Status City State Zip Country Details
TOI Clinical Research (ICIR) Cerritos California 90703 United States Details
City of Hope - Duarte (Main Campus) Duarte California 91010 United States Details
Providence Medical Group - Santa Rosa Santa Rosa California 95403 United States Details
SCL Health - Saint Joseph Hospital Cancer Center Lafayette Colorado 80026 United States Details
Rocky Mountain Cancer Centers - Lone Tree Lone Tree Colorado 80124 United States Details
Holy Cross Health Fort Lauderdale - Holy Cross Hospital Fort Lauderdale Florida 33308 United States Details
21st Century Oncology of Jacksonville - North Lee Street Jacksonville Florida 32204 United States Details
Cancer Specialists of North Florida - Southpoint Jacksonville Florida 32256 United States Details
Orlando Health University of Florida Health Cancer Center - Head and Neck Center Orlando Florida 32806 United States Details
USOR - Woodlands Medical Specialists Pensacola Florida 32503 United States Details
University Cancer & Blood Center (UCBC) - Athens Athens Georgia 30607 United States Details
Northwest Georgia Oncology Centers Wellstar - Marietta Marietta Georgia 30060 United States Details
University of Illinois Hospital & Health Sciences System Chicago Illinois 60612 United States Details
University of Chicago Chicago Illinois 60637 United States Details
Illinois Cancer Specialists - Niles Niles Illinois 60714 United States Details
Goshen Center for Cancer Care Goshen Indiana 46526 United States Details
Franciscan Health Cancer Center Indianapolis Indianapolis Indiana 46237 United States Details
Franciscan Health Munster Munster Indiana 46321 United States Details
University of Kansas Medical Center Westwood Kansas 66205 United States Details
Cancer Center of Kansas - Wichita - Heritage Plaza Wichita Kansas 67214 United States Details
Baptist Health Lexington Lexington Kentucky 40503 United States Details
Tulane University New Orleans Louisiana 70112 United States Details
New England Cancer Specialists - Scarborough Scarborough Maine 04074 United States Details
Frederick Health Frederick Maryland 21702 United States Details
Ascension Providence Cancer Center - Southfield Southfield Michigan 48075 United States Details
Central Care Cancer Center - Bolivar Bolivar Missouri 65613 United States Details
St. Vincent Healthcare Cancer Centers of Montana Billings Montana 59101 United States Details
Sisters of Charity of Leavenworth Health St. Marys Billings Montana 59102 United States Details
Astera Cancer Care - East Brunswick East Brunswick New Jersey 08816 United States Details
Holy Name Medical Center Teaneck New Jersey 07666 United States Details
SUNY Upstate Medical University Syracuse New York 13210-2306 United States Details
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 United States Details
Kettering Health Cancer Center - Main Campus Kettering Ohio 45429 United States Details
Oregon Oncology Specialists Salem Oregon 97301 United States Details
Lifespan Cancer Institute - Rhode Island Hospital Providence Rhode Island 02903 United States Details
Prisma Health Cancer Institute - Faris Road Greenville South Carolina 29605 United States Details
Avera Cancer Institute Sioux Falls South Dakota 57105 United States Details
Texas Oncology Dallas Fort Worth West (DFWW) - Arlington Cancer Center North Arlington Texas 76012 United States Details
Texas Oncology - South Austin Austin Texas 78745 United States Details
Local Institution - 012-999 Irving Texas 75063 United States Details
Texas Oncology - Sherman Sherman Texas 75090 United States Details
Utah Cancer Specialists - UCS Cancer Center Salt Lake City Utah 84106 United States Details
UVA Health - University Hospital Charlottesville Virginia 22908-0674 United States Details
NEXT Virginia Fairfax Virginia 22031 United States Details
Flinders Medical Centre Bedford Park 5042 Australia Details
Monash Health Clayton 3168 Australia Details
Townsville University Hospital Douglas 4814 Australia Details
GenesisCare - North Shore St. Leonards 2065 Australia Details
The Tweed Hospital Tweed Heads 2485 Australia Details
Cancer Care Wollongong Wollongong 2500 Australia Details
Princess Alexandra Hospital Woolloongabba 4102 Australia Details
Klinikum Klagenfurt Am Worthersee Klagenfurt Am Woerthersee 9020 Austria Details
Uniklinikum Salzburg Salzburg 5020 Austria Details
Wiener Gesundheitsverbund - Klinik Ottakring Wien 1160 Austria Details
Universitair Ziekenhuis Brussel Brussel 1090 Belgium Details
Grand Hopital de Charleroi - Notre Dame Charleroi 6000 Belgium Details
Universitair Ziekenhuis Antwerpen Edegem 2650 Belgium Details
Algemeen Ziekenhuis Maria Middelares Gent 9000 Belgium Details
Jessa Ziekenhuis - Campus Virga Jesse Hasselt 3500 Belgium Details
Algemeen Ziekenhuis Delta - Campus Rumbeke Roeselare 8800 Belgium Details
Algemeen Ziekenhuis Glorieux Ronse Ronse 9600 Belgium Details
Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne Yvoir B-5530 Belgium Details
Multiscan - Ambulance klinicke onkologie se stacionarem - Horovice Horovice 268 31 Czechia Details
Fakultni Nemocnice Olomouc Olomouc 779 00 Czechia Details
Fakultni nemocnice Bulovka Praha 8 - Liben 180 81 Czechia Details
Hopital Morvan Brest 29200 France Details
Hopital Louis Pradel Bron 69500 France Details
Centre Hospitalier Universitaire de Caen Normandie Caen Cedex 09 14033 France Details
Centre Francois Baclesse Caen Cedex 5 14076 France Details
Centre Hospitalier Intercommunal de Creteil Creteil 94000 France Details
Centre Georges Francois Leclerc Dijon cedex 21079 France Details
LHopital Nord-Ouest (HNO) - Villefranche-sur-Saone Gleize 69400 France Details
Hopital Michallon La Tronche 38700 France Details
Centre Hospitalier Regional Universitaire de Lille Lille Cedex 59037 France Details
Centre Hospitalier Universitaire Dupuytren 1 Limoges cedex 87042 France Details
Institut Paoli-Calmettes Marseille 13009 France Details
Hopital Nord de Marseille Marseille 13015 France Details
Hopital Arnaud de Villeneuve Montpellier 34090 France Details
Hopital Emile Muller Mulhouse 68100 France Details
Centre Antoine Lacassagne Nice Cedex 2 06189 France Details
Centre Hospitalier de Cornouaille - Hopital Laennec Quimper 29107 France Details
Institut de Cancerologie de lOuest - Saint-Herblain - Site Rene Gauducheau Saint Herblain 44805 France Details
Hopital Civil Strasbourg cedex 67091 France Details
Institut de Cancerologie Strasbourg Europe Strasbourg 67200 France Details
Hopital Bretonneau Tours Cedex 9 37044 France Details
Gustave Roussy Villejuif 94805 France Details
Zentralklinik Bad Berka Bad Berka 99437 Germany Details
Universitatsklinikum Bonn Bonn 53127 Germany Details
Kliniken Essen-Mitte - Evangelische Huyssens-Stiftung Essen 45136 Germany Details
Asklepios Fachkliniken Munchen-Gauting Gauting 82131 Germany Details
Universitatsklinikum Gieen und Marburg - Gieen Giessen 35392 Germany Details
LungenClinic Grosshansdorf Grohansdorf 22927 Germany Details
Krankenhaus Martha-Maria Halle-Dolau Halle 06120 Germany Details
Universitatsklinikum Jena Jena 07747 Germany Details
Klinikum Kassel Kassel 34125 Germany Details
Klinikum Koln-Merheim Koln 51109 Germany Details
SLK-Kliniken - Fachklinik Lowenstein Lowenstein 74245 Germany Details
Universitatsklinikum Schleswig-Holstein - Campus Lubeck Lubeck 23538 Germany Details
Munchen Klinik Bogenhausen Munchen 81925 Germany Details
Sana Klinikum Offenbach Offenbach 63069 Germany Details
Pius-Hospital Oldenburg Oldenburg 26121 Germany Details
Henry Dunant Hospital Center Athens 11526 Greece Details
General Hospital for Thoracic Diseases Sotiria Athens 11527 Greece Details
University General Hospital of Heraklion (PAGNI) Heraklion 71110 Greece Details
University General Hospital of Larissa Larissa 41110 Greece Details
"General Oncology Hospital of Kifisias "Agioi Anargyroi"" Nea Kifisia 145 64 Greece Details
Metropolitan Hospital Peiraias 185 47 Greece Details
BioClinic Thessaloniki Thessaloniki 54622 Greece Details
Interbalkan Medical Center of Thessaloniki Thessaloniki 57001 Greece Details
General Hospital of Thessaloniki George Papanikolaou Thessaloniki 57010 Greece Details
Anassa General Clinic Volos 38333 Greece Details
Humanity & Health Clinical Trial Centre Central 0 Hong Kong Details
Prince of Wales Hospital - Hong Kong Hong Kong 0 Hong Kong Details
Hong Kong United Oncology Centre Kowloon 0 Hong Kong Details
Semmelweis Egyetem - Pulmonologiai Klinika Budapest 1083 Hungary Details
Orszagos Koranyi Pulmonologiai Intezet Budapest 1121 Hungary Details
Orszagos Onkologiai Intezet Budapest 1122 Hungary Details
Matrai Gyogyintezet Gyongyos 3200 Hungary Details
Bekes Megyei Kozponti Korhaz - Pandy Kalman Tagkorhaz Gyula 5700 Hungary Details
Fejer Varmegyei Szent Gyorgy Egyetemi Oktato Korhaz Szekesfehervar 8000 Hungary Details
Reformatus Pulmonologiai Centrum Torokbalint 2045 Hungary Details
The Meath Foundation Tallaght Dublin D24 NR04 Ireland Details
St. Vincents University Hospital Dublin 4 Ireland Details
Beaumont Hospital - Dublin Dublin 9 Ireland Details
St. Jamess Hospital Dublin D08 NHY1 Ireland Details
University Hospital Galway Galway H91 YR71 Ireland Details
University Hospital Limerick Limerick V94 F858 Ireland Details
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo - Alessandria Alessandria 15121 Italy Details
Azienda Ospedaliera San Giuseppe Moscati - Avellino Avellino 83100 Italy Details
Centro di Riferimento Oncologico Aviano 33081 Italy Details
Istituto Tumori Bari Giovanni Paolo II - IRCCS Bari 70124 Italy Details
Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia Brescia 25123 Italy Details
Istituto di Candiolo - Fondazione del Piemonte per lOncologia Candiolo 10060 Italy Details
Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Garibaldi Catania 95122 Italy Details
Azienda Ospedaliero - Universitaria - Policlinico - Vittorio Emanuele Catania 95123 Italy Details
Azienda Ospedaliero - Universitaria Careggi Firenze 50134 Italy Details
ASL 3 Genovese - Ospedale Villa Scassi - Sampierdarena Genova 16100 Italy Details
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale Policlinico San Martino Genova 16132 Italy Details
Ospedale Vito Fazzi Lecce Lecce 73100 Italy Details
"Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST" Meldola 47014 Italy Details
Fondazione IRCCS - Istituto Nazionale dei Tumori Milano 20133 Italy Details
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele Milan 20132 Italy Details
Istituto Europeo di Oncologia Milan 20141 Italy Details
Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli Napoli 80131 Italy Details
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale Napoli 80131 Italy Details
Azienda Ospedaliero-Universitaria Maggiore della Carita di Novara Novara 28100 Italy Details
Azienda Ospedaliero-Universitaria di Parma Parma 43126 Italy Details
Azienda Ospedaliera di Perugia - Santa Maria della Misericordia Perugia 06132 Italy Details
Azienda Ospedaliera Ospedali Riuniti Marche Nord Pesaro 61122 Italy Details
Ospedale Santa Maria delle Croci di Ravenna Ravenna 48121 Italy Details
Azienda Ospedaliera Universitaria Integrata Verona Verona 37126 Italy Details
Pusan National University Hospital Busan-si 49241 Korea, Republic of Details
Inje University Haeundae Paik Hospital Busan 48108 Korea, Republic of Details
Kosin University Gospel Hospital Busan 602702 Korea, Republic of Details
Chungbuk National University Hospital Cheongju-si 28644 Korea, Republic of Details
Kyungpook National University Chilgok Hospital Daegu 41404 Korea, Republic of Details
Keimyung University Dongsan Hospital Daegu 42601 Korea, Republic of Details
Gachon University Gil Medical Center Incheon 21565 Korea, Republic of Details
Inha University Hospital Jung-Gu 400-712 Korea, Republic of Details
Cha Bundang Medical Center Seongnam-si 13496 Korea, Republic of Details
Seoul National University Bundang Hospital Seongnam-si 13620 Korea, Republic of Details
Korea University Anam Hospital Seoul 02841 Korea, Republic of Details
Severance Hospital - Yonsei Cancer Center Seoul 03722 Korea, Republic of Details
Konkuk University Medical Center Seoul 05080 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
The Catholic University of Korea - Seoul St. Marys Hospital Seoul 06591 Korea, Republic of Details
Catholic University of Korea Saint Vincents Hospital Suwon-Si 16247 Korea, Republic of Details
Ajou University Hospital Suwon-si 16499 Korea, Republic of Details
Amsterdam Universitair Medische Centra (UMC) - Locatie Vrije Universiteit Medisch Centrum Amsterdam 1081 HV Netherlands Details
Hagaziekenhuis Van Den Haag - Leyweg Den Haag 2545 AA Netherlands Details
Maastricht Universitair Medisch Centrum Maastricht 6229 HX Netherlands Details
Radboud Universitair Medisch Centrum Nijmegen 6525 GA Netherlands Details
St. Antonius Ziekenhuis - Ziekenhuis Utrecht Utrecht 3543 AZ Netherlands Details
Universitair Medisch Centrum Utrecht Utrecht 3584 CX Netherlands Details
Instytut MSF Lodz 90-302 Poland Details
MS Pnuemed - Janusz Milanowski, Katarzyna Szmygin-Milanowska Spolka Jawna Lublin 20-064 Poland Details
Specjalistyczna Praktyka Lekarska Slawomir Mandziuk Lublin 20-093 Poland Details
Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy Otwock 05-400 Poland Details
Mruk-Med I Sp. z o.o. Rzeszow 35-922 Poland Details
Pratia Poznan Skorzewo 60-185 Poland Details
Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu Torun 87-100 Poland Details
Wojskowy Instytut Medyczny Warsaw 04-349 Poland Details
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy Warszawa 02-781 Poland Details
Unidade Local de Saude de Almada-Seixal, E. P. E (Hospital Garcia de Orta) Almada 2805-267 Portugal Details
Unidade Local de Saude de Braga, E. P. E (Hospital de Braga) Braga 4710-243 Portugal Details
Instituto Portugues de Oncologia de Coimbra Francisco Gentil Coimbra 3000-075 Portugal Details
Unidade Local de Saude de Coimbra Coimbra 3000-075 Portugal Details
Unidade Local de Saude do Alto Ave, E. P. E (Hospital da Senhora da Oliveira Guimaraes) Guimaraes 4835-044 Portugal Details
Instituto Portugues De Oncologia De Lisboa Francisco Gentil Lisbon 1099-023 Portugal Details
The Champalimaud Centre for the Unknown Lisbon 1400-038 Portugal Details
Hospital CUF Descobertas Lisbon 1998-018 Portugal Details
Unidade Local de Saude de Loures-Odivelas, EPE (Hospital Beatriz Angelo) Loures 2674-514 Portugal Details
Hospital CUF Porto Porto 14341 Portugal Details
Unidade Local de Saude de Santo Antonio, E. P. E - Hospital Geral de Santo Antonio Porto 4099-001 Portugal Details
Instituto Portugues de Oncologia do Porto Francisco Gentil Porto 4200-072 Portugal Details
Unidade Local de Saude de Entre Douro e Vouga, E. P. E Santa Maria Da Feira 4520-211 Portugal Details
Unidade Local de Saude da Arrabida, E. P. E (Centro Hospitalar de Setubal) Setubal 2910-443 Portugal Details
Unidade Local de Saude de Gaia/Espinho, E. P. E Vila Nova de Gaia 4434-502 Portugal Details
Puerto Rico Medical Research Center San Juan 00919 Puerto Rico Details
Fundacion de Investigacion de Diego Clinical Research San Juan 00927 Puerto Rico Details
PanOncology Trials - Rio Piedras Medical Center San Juan 00935 Puerto Rico Details
Spitalul Jude�ean de Urgen�a dr. Constantin Opri� Baia Mare Baia Mare 430031 Romania Details
SC Policlinica de Diagnostic Rapid SA Brașov 500152 Romania Details
Institutul Oncologic Bucuresti - Prof. Dr. Alexandru Trestioreanu Bucharest 022328 Romania Details
Centrul Oncologic Sanador București 010991 Romania Details
Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj-Napoca 400015 Romania Details
Medisprof Cluj-Napoca 400641 Romania Details
Oncolab Craiova Craiova 200385 Romania Details
Centrul de Oncologie Sf Nectarie Craiova 200746 Romania Details
Centrul de Oncologie Euroclinic Iasi 700106 Romania Details
Ovidius Clinical Hospital Ovidiu 905900 Romania Details
SC OncoMed SRL Timisoara 300239 Romania Details
Oncocenter - Oncologie Clinica Timișoara 300166 Romania Details
Evimed Oncology Clinic Chelyabinsk 454048 Russian Federation Details
"Budgetary Healthcare Institution of the Udmurt Republic "Republican Clinical Oncological Dispensary n.a. Sergey Grigoryevich Pr Izhevsk 426067 Russian Federation Details
"Regional Budgetary Healthcare Institution "G.E. Ostroverkhov Kursk Oncology Scientific and Clinical Center" of the Healthcare C Kislino Village 305524 Russian Federation Details
VitaMed - Moscow Moscow 121309 Russian Federation Details
University Headache Clinic Moscow 121467 Russian Federation Details
State Budgetary Healthcare Institution of the Nizhny Novgorod Region Clinical Diagnostic Center Nizhniy Novgorod 603006 Russian Federation Details
"Limited Liability Company Medical Sanitary Unit "Clinicist-Clinic Pretor"" Novosibirsk 630099 Russian Federation Details
"Budgetary Healthcare Institution of Omsk region "Clinical Oncologic Dispensary"" Omsk 644013 Russian Federation Details
EuroCityClinic LLC Saint Petersburg 197022 Russian Federation Details
Saint Petersburg Clinical Scientific & Practical Center for Specialized Types of Medical Care (Oncology) Saint Petersburg 197758 Russian Federation Details
"Federal State Budgetary Institution "Influenza Research Institute named after N.N. A.A. Smorodintsev" of the Ministry of Health Saint-Petersburg 197376 Russian Federation Details
National Cancer Centre Singapore Singapore 168583 Singapore Details
Raffles Hospital Singapore 188770 Singapore Details
Icon Cancer Centre Farrer Park Singapore 217562 Singapore Details
Oncocare Cancer Centre Singapore 258499 Singapore Details
Parkway Cancer Centre - Gleneagles Hospital Singapore 258500 Singapore Details
Complejo Hospitalario Universitario A Coruna A Coruna 15006 Spain Details
Hospital General Universitario Dr. Balmis Alicante 3010 Spain Details
Hospital Germans Trias i Pujol Badalona 08916 Spain Details
Hospital Universitario Cruces Barakaldo 48903 Spain Details
Hospital del Mar - Parc de Salut Mar Barcelona 08003 Spain Details
Hospital Universitari Dexeus Barcelona 08028 Spain Details
Hospital Universitari Vall dHebron Barcelona 08035 Spain Details
Hospital Clinic de Barcelona Barcelona 08036 Spain Details
Hospital Universitario Reina Sofia Cordoba 14004 Spain Details
Institut Catala dOncologia Girona (ICO Girona) Girona 17007 Spain Details
Hospital Universitario Virgen de las Nieves Granada 18014 Spain Details
Complejo Hospitalario Universitario Insular Materno Infantil Las Palmas de Gran Canaria 35016 Spain Details
Hospital de Leon Leon 24008 Spain Details
Hospital Universitario Lucus Augusti Lugo 27003 Spain Details
Hospital Beata Maria Ana Madrid 28007 Spain Details
Clinica Universidad de Navarra - Madrid Madrid 28027 Spain Details
Hospital Universitario Ramon y Cajal Madrid 28034 Spain Details
Hospital Clinico San Carlos Madrid 28040 Spain Details
Hospital Universitario Fundacion Jimenez Diaz Madrid 28040 Spain Details
Hospital Universitario 12 de Octubre Madrid 28041 Spain Details
Hospital Universitario Puerta de Hierro - Majadahonda Majadahonda 28222 Spain Details
Hospital Regional Universitario de Malaga - Hospital Civil Malaga 29009 Spain Details
Hospital Universitario Son Espases Palma de Mallorca 07120 Spain Details
Hospital Universitario Marques de Valdecilla Santander 39008 Spain Details
Consorci Hospital General Universitari de Valencia Valencia 46014 Spain Details
Hospital Universitari i Politecnic La Fe Valencia 46026 Spain Details
Hospital Clinico Universitario Lozano Blesa Zaragoza 50009 Spain Details
Universitatsspital Basel Basel 4031 Switzerland Details
Kantonsspital Winterthur Winterthur 8401 Switzerland Details
University Hospital Birmingham NHS Foundation Trust Birmingham B15 2WB United Kingdom Details
NHS Lothian Edinburgh EH4 2XU United Kingdom Details
NHS Greater Glasgow and Clyde Glasgow G12 0XH United Kingdom Details
University Hospitals of Leicester NHS Trust Leicester LE1 5WW United Kingdom Details
The Christie NHS Foundation Trust Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from for the field