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NCT ID NCT04770896
Title A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab (IMbrave251)
Acronym IMbrave251
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Hoffmann-La Roche
Indications
Therapies
Age Groups: adult | senior
Covered Countries ITA | GBR | FRA | ESP | DEU | CAN | BEL | AUT

Facility Status City State Zip Country Details
Medizinische Universität Innsbruck; Universitätsklinik für Innere Medizin I Innsbruck 6020 Austria Details
Uniklinikum Salzburg, LKH; Univ.Klinik f. Innere Medizin III der PMU Salzburg 5020 Austria Details
Universitätsklinikum St. Pölten; Innere Medizin 2 St. Pölten 3100 Austria Details
Klinik Favoriten; Abteilung für Chirurgie Wien 1100 Austria Details
AZ KLINA Brasschaat 2930 Belgium Details
Hospital Erasme Bruxelles 1070 Belgium Details
Cliniques Universitaires St-Luc Bruxelles 1200 Belgium Details
UZ Leuven Leuven 3000 Belgium Details
AZ Delta (Campus Rumbeke) Roeselare 8800 Belgium Details
Hospital Felicio Rocho Belo Horizonte MG 30110-068 Brazil Details
Clinicas Oncologicas Integradas - COI Rio De Janeiro RJ 22290-160 Brazil Details
Hospital Moinhos de Vento Porto Alegre RS 90035-000 Brazil Details
Hospital Sao Lucas - PUCRS Porto Alegre RS 90610-000 Brazil Details
YNOVA Pesquisa Clinica Florianopolis SC 88020-210 Brazil Details
Beneficencia Portuguesa de Sao Paulo São Paulo SP 01321-00 Brazil Details
Multiprofile Hospital for Active Treatment Uni Hospital; Department of medicinal oncology Panagyurishte 4500 Bulgaria Details
Complex Oncological Center - Plovdiv, EOOD; Second Internal Department Plovdiv 4004 Bulgaria Details
Tom Baker Cancer Centre-Calgary Calgary Alberta T2N 4N2 Canada Details
Cross Cancer Institute Edmonton Alberta T6G 1Z2 Canada Details
Juravinski Cancer Centre Hamilton Ontario L8V 5C2 Canada Details
Princess Margaret Cancer Center Toronto Ontario M5G 2M9 Canada Details
Centro de Estudios Clínicos SAGA Santiago 7500653 Chile Details
The Fifth Medical Center of People's Liberation Army General Hospital Beijing City 100039 China Details
Hunan Cancer Hospital Changsha CITY 410013 China Details
Fujian Provincial Hospital Fuzhou City 350001 China Details
The First Affiliated Hospital, Sun Yat-sen University Guangzhou City 510080 China Details
Sun Yet-sen University Cancer Center Guangzhou City 510663 China Details
Nanfang Hospital, Southern Medical University Guangzhou 510515 China Details
Anhui Province Cancer Hospital Hefei City 230031 China Details
Shandong Cancer Hospital Jinan 250117 China Details
Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University) Nanjing City 210029 China Details
Zhongshan Hospital Fudan University Shanghai 200032 China Details
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200127 China Details
Shengjing Hospital of China Medical University ShenYang 110004 China Details
Tianjin Cancer Hospital Tianjin 300060 China Details
Clinica CIMCA San José 10103 Costa Rica Details
ICIMED Instituto de Investigación en Ciencias Médicas San José 10108 Costa Rica Details
Clinical Hospital Centre Zagreb Zagreb 10000 Croatia Details
AirForce Specialized Hospital; Clinical Oncology Cairo 11391 Egypt Details
North Estonia Medical Centre, Oncology and hematology Clinic; Department of Chemotherapy Tallinn 13419 Estonia Details
Tartu University Hospital; Clinic of Hematology and Oncology Tartu 50406 Estonia Details
TAYS Radius rakennus; onkologinen lääketutkimusyksikkö Tampere 33521 Finland Details
CHU Grenoble Sud; Service hépato-gastroentérologie GRENOBLE Cedex 9 38043 France Details
CHRU de Lille - Hopital Claude Huriez Lille 59037 France Details
Aphm; Cpcet Marseille 13385 France Details
CH Saint Eloi Montpellier 34295 France Details
CHU de Nantes - Hotel Dieu Nantes 44093 France Details
APHP - Hopital Saint Antoine Paris 75571 France Details
CHU Bordeaux Pessac 33604 France Details
Centre Eugene Marquis; Service d'oncologie; Direction de la Recherche Clinique Rennes 35042 France Details
CHU de Toulouse - Hôpital Rangueil Toulouse Cedex 09 31059 France Details
Hopitaux de Brabois - Gastro-Entereologie Vandoeuvre-les-nancy 54511 France Details
Hopital Paul Brousse; Centre Hepatologie Biliaire Villejuif 94804 France Details
Klinik Johann Wolfgang von Goethe Uni; Zentrum der Inneren Medizin; Medizinische Klinik I Frankfurt 60590 Germany Details
Med. Hochschule Hannover; Gastroenterologie Hannover 30625 Germany Details
Uniklinik Mainz; I. Medizinische Klinik Mainz 55131 Germany Details
Universität Tübingen; Med. Klinik; Innere Medizin I Tübingen 72076 Germany Details
Universitätsklinikum Ulm; Zentrum für Innere Medizin Klinik für Innere Medizin I Ulm 89081 Germany Details
Laiko General Hospital Athen; Uni Clinic of Gastrenterology Athens 115 27 Greece Details
Agioi Anargiroi Hospital of Kifissia; University Internal Medicine Clinic Nea Kifissia 14564 Greece Details
Tata Memorial Hospital; Dept of Medical Oncology Mumbai Maharashtra 400012 India Details
AIG Hospitals Gachibowli Telangana 500032 India Details
Rambam Health Care Campus; Oncology Haifa 3109601 Israel Details
Rabin Medical Center; Oncology Dept Petah Tikva 4910000 Israel Details
Sourasky Medical Center; Oncology Department Tel-Aviv 6423900 Israel Details
Fondazione Pascale; U.O. Sperimentazioni Cliniche Napoli Campania 80100 Italy Details
Azienda Osp Uni Seconda Università Degli Studi Di Napoli; Unità Operativa Oncologia Medica Napoli Campania 80131 Italy Details
Ospedale del Mare; UOC di Oncologia Napoli Campania 80147 Italy Details
A.O. S. Orsola Malpighi; Ambulatorio Epatocarcinoma (Bolondi) Bologna Emilia-Romagna 40138 Italy Details
Azienda Ospedaliera San Camillo Forlanini Roma Lazio 151 Italy Details
Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Lazio 00168 Italy Details
Fondazione IRCCS Ospedale Maggiore Policlinico; Gastroenterologia Milano Lombardia 20122 Italy Details
Azienda Ospedaliera Ordine Mauriziano di Torino Torino Piemonte 10128 Italy Details
A.O.U. Policlinico Paolo Giaccone; Gastroenterologia ed Epatologia Palermo Sicilia 90100 Italy Details
Azienda Ospedaliero-Universitaria Careggi;S.C. Oncologia Medica 1 Firenze Toscana 50139 Italy Details
Azlenda Ospendaliero-Universitaria Pisana; C.O. Oncologia 2 Pisa Toscana 56100 Italy Details
IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Seconda Padova Veneto 35128 Italy Details
Fujita Health University Hospital Aichi 470-1192 Japan Details
Chiba University Hospital Chiba 260-8677 Japan Details
National Cancer Center Hospital East Chiba 277-8577 Japan Details
Kurume University Hospital Fukuoka 830-0011 Japan Details
Hiroshima University Hospital Hiroshima 734-8551 Japan Details
Japanese Red Cross Society Himeji Hospital Hyogo 670-8540 Japan Details
Yokohama City University Medical Center Kanagawa 232-0024 Japan Details
Osaka University Hospital Osaka 565-0871 Japan Details
Kindai University Hospital Osaka 589-8511 Japan Details
Jichi Medical University Hospital Tochigi 329-0498 Japan Details
Toranomon Hospital Tokyo 105-8470 Japan Details
Japanese Red Cross Musashino Hospital Tokyo 180-8610 Japan Details
National Cancer Center Goyang-si 10408 Korea, Republic of Details
CHA Bundang Medical Center Gyeonggi-do 13496 Korea, Republic of Details
Severance Hospital, Yonsei University Health System Seoul 03722 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
Uni Malaya Medical Center; Clinical Oncology Unit, Menara Timur Kuala Lumpur FED. Territory OF Kuala Lumpur 59100 Malaysia Details
Institute Kanser Negara (IKN) Putrajaya FED. Territory OF Kuala Lumpur 62250 Malaysia Details
Beacon International Specialist Centre; Clinical Research Department, Level 2 Petaling Jaya, Selangor Selangor 46050 Malaysia Details
Cebu Doctors' University Hospital; Research Office Cebu City 6000 Philippines Details
Makati Medical Center Makati City 1229 Philippines Details
The Medical City; Cancer Center Pasig City 1600 Philippines Details
FSBI "National Medical Research Center of Oncology N.N. Blokhin? Moscow Moskovskaja Oblast 115478 Russian Federation Details
Moscow City Oncology Hospital #62; Outpatient Care Center Moscow Moskovskaja Oblast 125134 Russian Federation Details
Group of companies "Medci" Moskva Moskovskaja Oblast 105229 Russian Federation Details
I.M.Sechenov First Moscow State Medical University (1st MSMU) Moskva Moskovskaja Oblast 119991 Russian Federation Details
LLC "Oncology scientific centre" Pesochny Sankt Petersburg 197758 Russian Federation Details
University Medical Center Ljubljana; Clinical Dept. of Gastroenterology Ljubljana 1000 Slovenia Details
Corporacio Sanitaria Parc Tauli; Servicio de Hepatologia Sabadell Barcelona 08208 Spain Details
Hospital Son Llatzer; Servicio de Oncologia Palma de Mallorca Islas Baleares 07198 Spain Details
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia Santiago de Compostela LA Coruña 15706 Spain Details
Clinica Universitaria de Navarra; Servicio de Hepatologia Pamplona/iruña Navarra 31008 Spain Details
Hospital Universitari Vall d'Hebron; Servicio de Hepatologia Barcelona 08035 Spain Details
Hospital Universitario Reina Sofia; Servicio de Hepatologia Cordoba 14004 Spain Details
Hospital General Universitario Gregorio Marañon; Servicio de Aparato Digestivo Madrid 28007 Spain Details
Clinica Universidad de Navarra Madrid; Servicio de Oncología Madrid 28027 Spain Details
Hospital Clinico San Carlos; Servicio de Oncologia Madrid 28040 Spain Details
START Madrid. Centro Integral Oncologico Clara Campal; CIOCC Madrid 28050 Spain Details
Hospital Universitario la Fe; Servicio de Oncologia Valencia 46026 Spain Details
Hospital Universitario Miguel Servet; Servicio Oncologia Zaragoza 50009 Spain Details
Inselspital Bern Medizin Gastroenterologie Bern 3010 Switzerland Details
Universitätsspital Zürich Medizin Gastroenterologie; Klinik für Gastroenterologie und Hepatologie Zürich 8091 Switzerland Details
Chi-Mei Medical Centre; Hematology & Oncology Tainan 710 Taiwan Details
National Taiwan University Hospital; Oncology Zhongzheng Dist. 10048 Taiwan Details
Chulalongkorn Hospital; Medical Oncology Bangkok 10330 Thailand Details
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology Bangkok 10700 Thailand Details
Adana Ac?badem Hospital Oncology Department Adana 01130 Turkey Details
Memorial Ankara Hastanesi Ankara 06520 Turkey Details
Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji Bakirkoy / Istanbul 34147 Turkey Details
Uludag Uni Hospital; Oncology Bursa 16059 Turkey Details
Medipol Mega Üniversite Hastanesi Göztepe Istanbul 34214 Turkey Details
Ege Uni Medical Faculty Hospital; Oncology Dept Izmir 35100 Turkey Details
Hacettepe Uni Medical Faculty Hospital; Oncology Dept Sihhiye/Ankara 06230 Turkey Details
Ac?badem Altunizade Hastanesi; Oncology Üsküdar 34662 Turkey Details
Queen Elizabeth Hospital; Hepatobiliary Unit Birmingham B15 2TH United Kingdom Details
The Clatterbridge Cancer Centre NHS Foundation Trust Liverpool L7 8YA United Kingdom Details
Royal Free Hospital London NW3 2QS United Kingdom Details
King College Hospital NHS Foundation Trust London SE5 9RS United Kingdom Details
Hammersmith Hospital; Clinical trials unit London W12 0HS United Kingdom Details
Christie Hospital Nhs Trust; Medical Oncology Manchester M2O 4BX United Kingdom Details
Freeman Hospital; Gastroenterology & Liver Unit Newcastle Upon Tyne NE7 7DN United Kingdom Details
Churchill Hospital; Department of Oncology Oxford OX3 7LE United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field