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| NCT ID | NCT05301842 |
| Title | Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC (EMERALD-3) |
| Acronym | EMERALD-3 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | DEU | CAN | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | RECRUITING | Birmingham | Alabama | 35233 | United States | Details |
| Research Site | RECRUITING | Mobile | Alabama | 36607 | United States | Details |
| Research Site | RECRUITING | Yuma | Arizona | 85364 | United States | Details |
| Research Site | RECRUITING | Glendale | California | 91204 | United States | Details |
| Research Site | WITHDRAWN | Weston | Florida | 33331 | United States | Details |
| Research Site | RECRUITING | Atlanta | Georgia | 30318 | United States | Details |
| Research Site | RECRUITING | Shreveport | Louisiana | 71103 | United States | Details |
| Research Site | RECRUITING | Baltimore | Maryland | 21201 | United States | Details |
| Research Site | RECRUITING | Santa Fe | New Mexico | 87505 | United States | Details |
| Research Site | RECRUITING | Commack | New York | 11725 | United States | Details |
| Research Site | NOT_YET_RECRUITING | New York | New York | 10029 | United States | Details |
| Research Site | WITHDRAWN | Portland | Oregon | 97213 | United States | Details |
| Research Site | WITHDRAWN | Portland | Oregon | 97225 | United States | Details |
| Research Site | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Research Site | RECRUITING | Memphis | Tennessee | 38104 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Dallas | Texas | 75235 | United States | Details |
| Research Site | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Research Site | RECRUITING | Brussels | 1070 | Belgium | Details | |
| Research Site | RECRUITING | Gent | 9000 | Belgium | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Barretos | 14784-400 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Brasilia | 71681-603 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Niterói | 24020-096 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Porto Alegre | 91350-200 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Rio de Janeiro | 20231-050 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Santa Maria | 97015-450 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Santo Andre | 09060-650 | Brazil | Details | |
| Research Site | SUSPENDED | São Paulo | 04014-002 | Brazil | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Vitória | 29043-272 | Brazil | Details | |
| Research Site | RECRUITING | Calgary | Alberta | T2N 4N2 | Canada | Details |
| Research Site | RECRUITING | Moncton | New Brunswick | E1C 6Z8 | Canada | Details |
| Research Site | RECRUITING | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details |
| Research Site | RECRUITING | Kingston | Ontario | K7L 5P9 | Canada | Details |
| Research Site | WITHDRAWN | London | Ontario | N6C 2R5 | Canada | Details |
| Research Site | RECRUITING | Ottawa | Ontario | K1H 8L6 | Canada | Details |
| Research Site | RECRUITING | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Research Site | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H2X 3E4 | Canada | Details |
| Research Site | RECRUITING | Montreal | Quebec | H4A 3J1 | Canada | Details |
| Research Site | ACTIVE_NOT_RECRUITING | Beijing | 100021 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Beijing | 100069 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Beijing | 100142 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Changchun | 130021 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Changsha | 410013 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Chengdu | 610041 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Fuzhou | 350001 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Fuzhou | 350011 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Guangzhou | 510060 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Guangzhou | 510515 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Haikou | 570311 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hangzhou | 310022 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Harbin | 150081 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hefei | 230031 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Lanzhou | 730030 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Lishui | 323000 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Nanchang | 330006 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Nanjing | 210002 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Nantong | 226361 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Neijiang | 641000 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Shanghai | 200032 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Suzhou | 215004 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Tianjin | 300170 | China | Details | |
| Research Site | WITHDRAWN | Urumqi | 830000 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Wenzhou | 325000 | China | Details | |
| Research Site | WITHDRAWN | Wuhan | 430010 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Wuhan | 430010 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Wuhan | 430022 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Xi'an | 710000 | China | Details | |
| Research Site | WITHDRAWN | Zhengzhou | 450000 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Zhengzhou | 450008 | China | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Zhuhai | 519000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Alexandria | 21131 | Egypt | Details | |
| Research Site | NOT_YET_RECRUITING | Cairo | 11451 | Egypt | Details | |
| Research Site | NOT_YET_RECRUITING | Luxor | 85863 | Egypt | Details | |
| Research Site | NOT_YET_RECRUITING | Mansoura | 7650001 | Egypt | Details | |
| Research Site | NOT_YET_RECRUITING | New Cairo | 11566 | Egypt | Details | |
| Research Site | NOT_YET_RECRUITING | Shebeen El Kom | 32511 | Egypt | Details | |
| Research Site | RECRUITING | Angers | 49933 | France | Details | |
| Research Site | RECRUITING | Clichy | 92110 | France | Details | |
| Research Site | RECRUITING | Creteil | 94010 | France | Details | |
| Research Site | RECRUITING | MONTPELLIER Cedex 5 | 34295 | France | Details | |
| Research Site | RECRUITING | Nantes cedex 1 | 44093 | France | Details | |
| Research Site | RECRUITING | Nice | 06200 | France | Details | |
| Research Site | RECRUITING | Paris | 75013 | France | Details | |
| Research Site | WITHDRAWN | Rennes | 35000 | France | Details | |
| Research Site | RECRUITING | Strasbourg | 67091 | France | Details | |
| Research Site | RECRUITING | Toulouse | 31059 | France | Details | |
| Research Site | RECRUITING | Vandoeuvre Les Nancy | 54511 | France | Details | |
| Research Site | RECRUITING | Bonn | 53127 | Germany | Details | |
| Research Site | RECRUITING | Chemnitz | 09116 | Germany | Details | |
| Research Site | RECRUITING | Dresden | 01307 | Germany | Details | |
| Research Site | RECRUITING | Düsseldorf | 40225 | Germany | Details | |
| Research Site | RECRUITING | Frankfurt | 60596 | Germany | Details | |
| Research Site | RECRUITING | Göttingen | 37075 | Germany | Details | |
| Research Site | RECRUITING | Hamburg | 22291 | Germany | Details | |
| Research Site | RECRUITING | Hannover | 30625 | Germany | Details | |
| Research Site | RECRUITING | Heidelberg | 69120 | Germany | Details | |
| Research Site | RECRUITING | Kiel | 24105 | Germany | Details | |
| Research Site | RECRUITING | Leipzig | 04103 | Germany | Details | |
| Research Site | RECRUITING | Magdeburg | 39120 | Germany | Details | |
| Research Site | RECRUITING | Ulm | 89081 | Germany | Details | |
| Research Site | RECRUITING | Ahmedabad | 380052 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Ahmedabad | 380054 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Ahmedabad | 380060 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Bangalore | 560027 | India | Details | |
| Research Site | WITHDRAWN | Bangalore | 560092 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Delhi | 110029 | India | Details | |
| Research Site | WITHDRAWN | Gurgaon | 122002 | India | Details | |
| Research Site | RECRUITING | Gurugram | 122001 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hyderabad | 500032 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | JAipur | 302022 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Kolkata | 700099 | India | Details | |
| Research Site | WITHDRAWN | Ludhiana | 141001 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Mumbai | 400012 | India | Details | |
| Research Site | RECRUITING | Nagpur | 440001 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | New Delhi | 110 085 | India | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | New Delhi | 110005 | India | Details | |
| Research Site | RECRUITING | Rishikesh | 249203 | India | Details | |
| Research Site | RECRUITING | Arezzo | 52100 | Italy | Details | |
| Research Site | RECRUITING | Firenze | 50134 | Italy | Details | |
| Research Site | RECRUITING | Milano | 20132 | Italy | Details | |
| Research Site | RECRUITING | Milano | 20133 | Italy | Details | |
| Research Site | RECRUITING | Roma | 00128 | Italy | Details | |
| Research Site | RECRUITING | Rozzano | 20089 | Italy | Details | |
| Research Site | RECRUITING | Tricase | 73039 | Italy | Details | |
| Research Site | RECRUITING | Chuo-ku | 104-0045 | Japan | Details | |
| Research Site | RECRUITING | Fukuoka-shi | 810-8563 | Japan | Details | |
| Research Site | RECRUITING | Hiroshima-shi | 734-8551 | Japan | Details | |
| Research Site | RECRUITING | Kashihara-shi | 634-8522 | Japan | Details | |
| Research Site | RECRUITING | Kashiwa | 277-8577 | Japan | Details | |
| Research Site | RECRUITING | Kumamoto-shi | 860-8556 | Japan | Details | |
| Research Site | RECRUITING | Mitaka-shi | 181-8611 | Japan | Details | |
| Research Site | RECRUITING | Morioka-shi | 028-3695 | Japan | Details | |
| Research Site | RECRUITING | Musashino-shi | 180-8610 | Japan | Details | |
| Research Site | RECRUITING | Okayama-shi | 700-8558 | Japan | Details | |
| Research Site | RECRUITING | Osaka-shi | 543-8555 | Japan | Details | |
| Research Site | RECRUITING | Osaka-shi | 545-8586 | Japan | Details | |
| Research Site | RECRUITING | Osakasayama-shi | 589-8511 | Japan | Details | |
| Research Site | RECRUITING | Sapporo-shi | 006-8555 | Japan | Details | |
| Research Site | RECRUITING | Sendai-shi | 980-0873 | Japan | Details | |
| Research Site | RECRUITING | Sunto-gun | 411-8777 | Japan | Details | |
| Research Site | RECRUITING | Tokushima-shi | 770-8503 | Japan | Details | |
| Research Site | RECRUITING | Tsu-shi | 514-8507 | Japan | Details | |
| Research Site | RECRUITING | Yokohama-shi | 241-8515 | Japan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Busan | 49241 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Daegu | 42601 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Goyang-si | 10408 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Jung-gu | 41944 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | George Town | 10450 | Malaysia | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Kuching | 93586 | Malaysia | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Puncak Alam | 42300 | Malaysia | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Selangor | 62250 | Malaysia | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Guadalajara, Jalisco | 44280 | Mexico | Details | |
| Research Site | COMPLETED | México | 1400 | Mexico | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | San Luis Potosí | 78209 | Mexico | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Tuxtla Gutierrez | 29090 | Mexico | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Davao City | 8000 | Philippines | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Makati | 1229 | Philippines | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Manila | 1003 | Philippines | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Pasig City | 1600 | Philippines | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Quezon City | 1112 | Philippines | Details | |
| Research Site | RECRUITING | Lisboa | 1649-035 | Portugal | Details | |
| Research Site | RECRUITING | Vila Real | 5000-508 | Portugal | Details | |
| Research Site | RECRUITING | Hato Rey Central | 00917 | Puerto Rico | Details | |
| Research Site | RECRUITING | San Juan | 00927 | Puerto Rico | Details | |
| Research Site | WITHDRAWN | Moscow | 115478 | Russian Federation | Details | |
| Research Site | WITHDRAWN | Moscow | 143442 | Russian Federation | Details | |
| Research Site | RECRUITING | Ar Riyāḑ | 11426 | Saudi Arabia | Details | |
| Research Site | RECRUITING | Dammam | 31444 | Saudi Arabia | Details | |
| Research Site | RECRUITING | Jeddah | 22384 | Saudi Arabia | Details | |
| Research Site | RECRUITING | Riyadh | 12713 | Saudi Arabia | Details | |
| Research Site | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Research Site | RECRUITING | Barcelona | 8035 | Spain | Details | |
| Research Site | RECRUITING | Cordoba | 14004 | Spain | Details | |
| Research Site | RECRUITING | Madrid | 28007 | Spain | Details | |
| Research Site | RECRUITING | Madrid | 28034 | Spain | Details | |
| Research Site | RECRUITING | San Sebastian | 20014 | Spain | Details | |
| Research Site | RECRUITING | Taichung | 40447 | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Taichung | 40705 | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Tainan City | 70403 | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Taipei | 100 | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Taipei | TAIWAN | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Bangkok | 10210 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Bangkok | 10300 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Bangkok | 10400 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Chiang Mai | 50200 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hat Yai | 90110 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Khon Kaen | 40002 | Thailand | Details | |
| Research Site | WITHDRAWN | Phisanulok | 65000 | Thailand | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Ha Noi | 100000 | Vietnam | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hanoi | 100000 | Vietnam | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hcmc | 700000 | Vietnam | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Hcmc | 70000 | Vietnam | Details | |
| Research Site | ACTIVE_NOT_RECRUITING | Ho Chi Minh | 700000 | Vietnam | Details |