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| NCT ID | NCT05445843 |
| Title | Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression >= 1% and an STK11 Co-mutation. |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | ESP | DEU | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Hartford Hospital | RECRUITING | Hartford | Connecticut | 06102 | United States | Details |
| University of Toledo Precision Oncology | RECRUITING | Toledo | Ohio | 43606 | United States | Details |
| The Brown University Oncology Group | RECRUITING | Providence | Rhode Island | 02903 | United States | Details |
| Novartis Investigative Site | RECRUITING | Pilar | Buenos Aires | B1629AHJ | Argentina | Details |
| Novartis Investigative Site | RECRUITING | Buenos Aires | Caba | C1431FWO | Argentina | Details |
| Novartis Investigative Site | RECRUITING | Rosario | Santa Fe | S2000DSV | Argentina | Details |
| Novartis Investigative Site | RECRUITING | Buenos Aires | C1426AGE | Argentina | Details | |
| Novartis Investigative Site | RECRUITING | Cordoba | X5000JHQ | Argentina | Details | |
| Novartis Investigative Site | RECRUITING | Cordoba | X5016KEH | Argentina | Details | |
| Novartis Investigative Site | RECRUITING | Feldkirch | A 6807 | Austria | Details | |
| Novartis Investigative Site | RECRUITING | Klagenfurt | 9020 | Austria | Details | |
| Novartis Investigative Site | RECRUITING | Wels | A-4600 | Austria | Details | |
| Novartis Investigative Site | RECRUITING | Sint Niklaas | Oost Vlaanderen | 9100 | Belgium | Details |
| Novartis Investigative Site | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Novartis Investigative Site | RECRUITING | Salvador | BA | 41825-010 | Brazil | Details |
| Novartis Investigative Site | RECRUITING | Belo Horizonte | 30360 680 | Brazil | Details | |
| Novartis Investigative Site | RECRUITING | Rio de Janeiro | 22271-110 | Brazil | Details | |
| Novartis Investigative Site | RECRUITING | Rio Grande Do Sul | 90035-001 | Brazil | Details | |
| Novartis Investigative Site | RECRUITING | Branipole | 4109 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Plovdiv | 4004 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Sofia | 1303 | Bulgaria | Details | |
| Novartis Investigative Site | WITHDRAWN | Guang Zhou | Guang Dong Province | 510120 | China | Details |
| Novartis Investigative Site | RECRUITING | Wuhan | Hubei | 430022 | China | Details |
| Novartis Investigative Site | RECRUITING | Wuhan | Hubei | 430030 | China | Details |
| Novartis Investigative Site | RECRUITING | Changsha | Hunan | 410013 | China | Details |
| Novartis Investigative Site | RECRUITING | Xian | Shanxi | 710061 | China | Details |
| Novartis Investigative Site | RECRUITING | Beijing | 100021 | China | Details | |
| Novartis Investigative Site | RECRUITING | Beijing | 100036 | China | Details | |
| Novartis Investigative Site | RECRUITING | Shanyang | 110005 | China | Details | |
| Novartis Investigative Site | RECRUITING | Zhengzhou | 450008 | China | Details | |
| Novartis Investigative Site | RECRUITING | Marseille cedex 20 | Bouches Du Rhone | 13915 | France | Details |
| Novartis Investigative Site | RECRUITING | Bron | 69677 | France | Details | |
| Novartis Investigative Site | RECRUITING | Montpellier | 34070 | France | Details | |
| Novartis Investigative Site | RECRUITING | Paris | 75014 | France | Details | |
| Novartis Investigative Site | RECRUITING | Paris | 75970 | France | Details | |
| Novartis Investigative Site | RECRUITING | Saint Herblain | 44805 | France | Details | |
| Novartis Investigative Site | RECRUITING | Strasbourg Cedex | 67091 | France | Details | |
| Novartis Investigative Site | RECRUITING | Berlin | 13125 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Halle (Saale) | 06120 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Harburg | 31787 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Hemer | 58675 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Kempten | 87439 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Oldenburg | 26121 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Tuebingen | 72076 | Germany | Details | |
| Novartis Investigative Site | RECRUITING | Athens | GR | 115 27 | Greece | Details |
| Novartis Investigative Site | RECRUITING | Athens | 11526 | Greece | Details | |
| Novartis Investigative Site | RECRUITING | Torokbalint | Pest | 2045 | Hungary | Details |
| Novartis Investigative Site | RECRUITING | Matrahaza | 3200 | Hungary | Details | |
| Novartis Investigative Site | RECRUITING | Varanasi | Uttarpradesh | 221005 | India | Details |
| Novartis Investigative Site | RECRUITING | Kolkata | West Bengal | 700160 | India | Details |
| Novartis Investigative Site | RECRUITING | Puducherry | 605006 | India | Details | |
| Novartis Investigative Site | RECRUITING | Bari | BA | 70124 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Rozzano | MI | 20089 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Roma | RM | 00128 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Orbassano | TO | 10043 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Varese | VA | 21100 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Alor Setar | Kedah | 05460 | Malaysia | Details |
| Novartis Investigative Site | RECRUITING | Kuantan | Pahang | 25200 | Malaysia | Details |
| Novartis Investigative Site | RECRUITING | Kuching | Sarawak | 93586 | Malaysia | Details |
| Novartis Investigative Site | RECRUITING | Pulau Pinang | 10990 | Malaysia | Details | |
| Novartis Investigative Site | RECRUITING | Breda | 4818 CK | Netherlands | Details | |
| Novartis Investigative Site | RECRUITING | Leeuwarden | 8934 AD | Netherlands | Details | |
| Novartis Investigative Site | RECRUITING | Lisboa | 1998-018 | Portugal | Details | |
| Novartis Investigative Site | RECRUITING | Porto | 4100-180 | Portugal | Details | |
| Novartis Investigative Site | RECRUITING | Singapore | 168583 | Singapore | Details | |
| Novartis Investigative Site | RECRUITING | Sevilla | Andalucia | 41013 | Spain | Details |
| Novartis Investigative Site | RECRUITING | Santander | Cantabria | 39008 | Spain | Details |
| Novartis Investigative Site | RECRUITING | Barcelona | Catalunya | 08035 | Spain | Details |
| Novartis Investigative Site | RECRUITING | Madrid | 28041 | Spain | Details | |
| Novartis Investigative Site | RECRUITING | Songkhla | Hat Yai | 90110 | Thailand | Details |
| Novartis Investigative Site | RECRUITING | Bangkok | 10400 | Thailand | Details | |
| Novartis Investigative Site | RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Novartis Investigative Site | RECRUITING | Adana | 01140 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Ankara | 06560 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Diyarbakir | 21000 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Izmir | 35575 | Turkey | Details | |
| Novartis Investigative Site | RECRUITING | Torquay | Devon | TQ2 7AA | United Kingdom | Details |