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| NCT ID | NCT05456191 |
| Title | A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (>=18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START) |
| Acronym | ASC4START |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Novartis Pharmaceuticals |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | GBR | FRA | DEU | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Arizona Oncology Associates . | RECRUITING | Phoenix | Arizona | 85016 | United States | Details |
| Kaiser Permanente-California South Kaiser - Irvine | RECRUITING | San Diego | California | 92120 | United States | Details |
| Rocky Mountain Cancer Centers USOR | ACTIVE_NOT_RECRUITING | Boulder | Colorado | 80304 | United States | Details |
| Florida Cancer Specialists Dept of Oncology 2 | RECRUITING | Fort Myers | Florida | 33901 | United States | Details |
| Florida Cancer Specialists Pan . | RECRUITING | Tallahassee | Florida | 32308 | United States | Details |
| Illinois Cancer Care | RECRUITING | Peoria | Illinois | 61615 | United States | Details |
| Hematology and Oncology Clinic . | RECRUITING | Baton Rouge | Louisiana | 70809 | United States | Details |
| Minnesota Oncology Hematology P A Minnesota Oncology Hematology | RECRUITING | Minneapolis | Minnesota | 55404 | United States | Details |
| Regions Hospital Oncology Research Consortium | ACTIVE_NOT_RECRUITING | Saint Paul | Minnesota | 55101 | United States | Details |
| Messino Cancer Centers | RECRUITING | Asheville | North Carolina | 28806 | United States | Details |
| Oncology Hematology Care Inc . | ACTIVE_NOT_RECRUITING | Cincinnati | Ohio | 45242 | United States | Details |
| Williamette Cancer Center | ACTIVE_NOT_RECRUITING | Eugene | Oregon | 97401 | United States | Details |
| Sarah Cannon Research Institute HCA Healthcare Research Inst | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Texas Oncology P A . | RECRUITING | Bedford | Texas | 76022 | United States | Details |
| Texas Oncology PA Bedford | RECRUITING | Bedford | Texas | 76022 | United States | Details |
| Texas Oncology Midtown | RECRUITING | Dallas | Texas | 75251 | United States | Details |
| Lumi Research | RECRUITING | Kingwood | Texas | 77339 | United States | Details |
| Virginia Oncology Associates VOA - Princess Anne | RECRUITING | Norfolk | Virginia | 23502 | United States | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Caba | Buenos Aires | C1181ACH | Argentina | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Caba | Buenos Aires | C1221ADH | Argentina | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Buenos aires | C1039AAC | Argentina | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Buenos Aires | C1114AAN | Argentina | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Buenos Aires | C1425AUM | Argentina | Details | |
| Novartis Investigative Site | RECRUITING | Pleven | 5800 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Plovdiv | 4002 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Sofia | 1413 | Bulgaria | Details | |
| Novartis Investigative Site | WITHDRAWN | Sofia | 1431 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Sofia | 1797 | Bulgaria | Details | |
| Novartis Investigative Site | RECRUITING | Varna | 9010 | Bulgaria | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | London | Ontario | N6A 4G4 | Canada | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Brno Bohunice | Czech Republic | 625 00 | Czechia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Praha 2 | Czech Republic | 128 20 | Czechia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Plzen-Bory | 30599 | Czechia | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Praha 10 | 100 34 | Czechia | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bordeaux | 33076 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Caen Cedex | 14033 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Clermont Ferrand | 63003 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Lille | 59037 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Lyon | 69373 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Marseille | 13273 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Nantes Cedex 1 | 44093 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Nice | 06202 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Paris 10 | 75475 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Poitiers | 86000 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Strasbourg | 67200 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Toulouse | 31059 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Vandoeuvre les Nancy cedex | 54511 | France | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Mannheim | Baden Wuerttemberg | 68305 | Germany | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Muenchen | Bayern | 81241 | Germany | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Velbert | North Rhine-Westphalia | 42551 | Germany | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Dresden | Sachsen | 01307 | Germany | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Aachen | 52074 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Augsburg | 86179 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bad Saarow | 15526 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bayreuth | 95445 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Berlin | 13353 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bonn | 53105 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bremen | 28177 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Chemnitz | 09113 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Erlangen | 91054 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Essen | 45147 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Frankfurt | 60590 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Freiburg | 79106 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Halle S | 06120 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Hamburg | 20246 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Hannover | 30161 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Heidelberg | 69120 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Jena | 07740 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Leipzig | 04103 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Luebeck | 23538 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Magdeburg | 39104 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Marburg | 35039 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Muenchen | 80377 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Paderborn | 33098 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Regensburg | 93049 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Tuebingen | 72076 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Ulm | 89081 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Wuerzburg | 97080 | Germany | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Ioannina | GR | 455 00 | Greece | Details |
| Novartis Investigative Site | WITHDRAWN | Larissa | GR | 411 10 | Greece | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Thessaloniki | GR | 570 10 | Greece | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Athens | 106 76 | Greece | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Athens | 115 27 | Greece | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Patras | 265 00 | Greece | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Budapest | 1085 | Hungary | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Budapest | 1097 | Hungary | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Eger | 3300 | Hungary | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Ahmedabad | Gujrat | 380009 | India | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Chennai | Tamilnadu | 600036 | India | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Varanasi | Uttar Pradesh | 221010 | India | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Rishikesh | Uttarakhand | 249203 | India | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | New Delhi | 110029 | India | Details | |
| Novartis Investigative Site | WITHDRAWN | Bari | BA | 70124 | Italy | Details |
| Novartis Investigative Site | RECRUITING | Meldola | FC | 47014 | Italy | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Milano | MI | 20162 | Italy | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Pisa | PI | 56126 | Italy | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Roma | RM | 00144 | Italy | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Torino | TO | 10126 | Italy | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Amman | 11941 | Jordan | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bundang Gu | Gyeonggi Do | 13620 | Korea, Republic of | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Uijeongbu si | Gyeonggi Do | 11759 | Korea, Republic of | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Alor Setar | Kedah | 05460 | Malaysia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Kuching | Sarawak | 93586 | Malaysia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Petaling Jaya | Selangor Darul Ehsan | 46150 | Malaysia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Novartis Investigative Site | WITHDRAWN | Penang | 10050 | Malaysia | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Dordrecht | 3318AT | Netherlands | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Muscat | 123 | Oman | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bucharest | District 2 | 022328 | Romania | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Tg Mures | Mures | 540136 | Romania | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bucharest | 030 171 | Romania | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bucuresti | 021494 | Romania | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Cluj-Napoca | 400124 | Romania | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Craiova | 200136 | Romania | Details | |
| Novartis Investigative Site | RECRUITING | Sibiu | 550245 | Romania | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Timisoara | 300079 | Romania | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Singapore | 119228 | Singapore | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Singapore | 169608 | Singapore | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Singapore | S308433 | Singapore | Details | |
| Novartis Investigative Site | WITHDRAWN | Kosice | Slovak Republic | 040 66 | Slovakia | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Bratislava | 85107 | Slovakia | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Soweto | Gauteng | 2013 | South Africa | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Pretoria | 0044 | South Africa | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Genève | 1211 | Switzerland | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Istanbul | TUR | 34098 | Turkey | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Ankara | 06100 | Turkey | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Izmir | 35040 | Turkey | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Abu Dhabi | United Arab Emirates | Details | ||
| Novartis Investigative Site | RECRUITING | Truro | Cornwall | TR1 3LJ | United Kingdom | Details |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Glasgow | G12 0YN | United Kingdom | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Gloucester | GL1 3NN | United Kingdom | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | Gwent | NP9 2UB | United Kingdom | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | London | SE5 9RS | United Kingdom | Details | |
| Novartis Investigative Site | ACTIVE_NOT_RECRUITING | London | W12 0HS | United Kingdom | Details |