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| NCT ID | NCT05722015 |
| Title | A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Hyaluronidase (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | FRA | ESP |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| St. Joseph's Hospital and Medical Center-Dignity Health Cancer Institute ( Site 0023) | Phoenix | Arizona | 85004 | United States | Details | |
| Clermont Oncology Center ( Site 0018) | Clermont | Florida | 34711 | United States | Details | |
| Mid Florida Hematology and Oncology Center ( Site 0010) | Orange City | Florida | 32763 | United States | Details | |
| University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0022) | Chicago | Illinois | 60612 | United States | Details | |
| Orchard Healthcare Research Inc. ( Site 0011) | Skokie | Illinois | 60077 | United States | Details | |
| Franciscan Health Lafayette East ( Site 0020) | Lafayette | Indiana | 47905 | United States | Details | |
| Mercy Health-Paducah Medical Oncology and Hematology ( Site 0006) | Paducah | Kentucky | 42003 | United States | Details | |
| Hattiesburg Clinic Hematology/Oncology ( Site 0008) | Hattiesburg | Mississippi | 39401 | United States | Details | |
| Central Care Cancer Center - Bolivar ( Site 0017) | Bolivar | Missouri | 65613 | United States | Details | |
| Instituto Alexander Fleming ( Site 1008) | Ciudad Autónoma de Buenos Aires | Buenos Aires | C1426ANZ | Argentina | Details | |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 1001) | Mar del Plata | Buenos Aires | B7600FZO | Argentina | Details | |
| Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 1005) | ABB | Caba | C1199ABB | Argentina | Details | |
| Sanatorio Parque ( Site 1003) | Rosario | Santa Fe | S2000DSV | Argentina | Details | |
| Instituto Argentino de Diagnóstico y Tratamiento (IADT) ( Site 1002) | Buenos Aires | C1122AAL | Argentina | Details | ||
| Clinica Adventista Belgrano-Oncology ( Site 1004) | Caba | C1430EGF | Argentina | Details | ||
| Hospital Italiano de Córdoba ( Site 1000) | Cordoba | 5000 | Argentina | Details | ||
| CRIO - CENTRO REGIONAL INTEGRADO DE ONCOLOGIA-Pesquisa Clínica ( Site 1102) | Fortaleza | Ceara | 60336232 | Brazil | Details | |
| Hospital de Câncer de Recife ( Site 1107) | Recife | Pernambuco | 50040-000 | Brazil | Details | |
| Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 1100) | Porto Alegre | Rio Grande Do Sul | 91350-200 | Brazil | Details | |
| Instituto Joinvilense de Hematologia e Oncologia ( Site 1101) | Joinville | Santa Catarina | 89201260 | Brazil | Details | |
| A. C. Camargo Cancer Center ( Site 1106) | Sao Paulo | 01509-010 | Brazil | Details | ||
| IC La Serena Research ( Site 1207) | La Serena | Coquimbo | 1720430 | Chile | Details | |
| Oncocentro Valdivia ( Site 1201) | Valdivia | Los Rios | 5112129 | Chile | Details | |
| FALP-UIDO ( Site 1203) | Santiago | Region M. De Santiago | 7500921 | Chile | Details | |
| Oncovida ( Site 1209) | Santiago | Region M. De Santiago | 7510032 | Chile | Details | |
| Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 1210) | Santiago | Region M. De Santiago | 8330032 | Chile | Details | |
| Instituto Nacional del Cancer-CR Investigación ( Site 1211) | Santiago | Region M. De Santiago | 8380455 | Chile | Details | |
| Bradfordhill-Clinical Area ( Site 1202) | Santiago | Region M. De Santiago | 8420383 | Chile | Details | |
| Anhui Provincial Hospital-Cancer Chemotherapy Department ( Site 4503) | Hefei | Anhui | 230071 | China | Details | |
| Beijing Cancer hospital-intrathoratic deparmtment II ( Site 4510) | Beijing | Beijing | 100142 | China | Details | |
| Beijing Peking Union Medical College Hospital-pneumology department ( Site 4501) | Beijing | Beijing | 100730 | China | Details | |
| Beijing Chest Hospital,Capital Medical University ( Site 4511) | Beijing | Beijing | 101149 | China | Details | |
| Chongqing Three Gorges Central Hospital ( Site 4516) | Wanzhou | Chongqing | 404199 | China | Details | |
| Fujian Provincial Cancer Hospital ( Site 4517) | Fuzhou | Fujian | 350014 | China | Details | |
| Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( | Guangzhou | Guangdong | 510515 | China | Details | |
| Jiangmen Center Hospital ( Site 4509) | Jiangmen | Guangdong | 529030 | China | Details | |
| ShenZhen People's Hospital ( Site 4504) | Shenzhen | Guangdong | 518020 | China | Details | |
| Wuhan Union Hospital Cancer Center-Cancer center ( Site 4502) | Wuhan | Hubei | 430022 | China | Details | |
| The First Affiliated Hospital of Nanchang University-Respiratory Medicine Department ( Site 4515) | Nanchang | Jiangxi | 330006 | China | Details | |
| The First Affiliated Hospital of Xi'an Jiaotong University ( Site 4520) | Xi'an | Shaanxi | 710061 | China | Details | |
| Fudan University Shanghai Cancer Center-Oncology ( Site 4512) | Shanghai | Shanghai | 200032 | China | Details | |
| Shanxi Cancer Hospital ( Site 4521) | Taiyuan | Shanxi | 030000 | China | Details | |
| Tianjin Chest Hospital ( Site 4518) | Tianjin | Tianjin | 300051 | China | Details | |
| The First Affiliated Hospital, Zhejiang University-Respiratory Department ( Site 4514) | Hangzhou | Zhejiang | 310006 | China | Details | |
| Taizhou Hospital of Zhejiang Province-Respiratory ( Site 4508) | Taizhou | Zhejiang | 317000 | China | Details | |
| Centre Hospitalier de Cornouaille Quimper - Concarneau ( Site 2600) | Quimper | Finistere | 29107 | France | Details | |
| Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau ( Site 2602) | Tours | Indre-et-Loire | 37044 | France | Details | |
| Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 2603) | Paris | 75014 | France | Details | ||
| Private Practice- Dr. Rixci Augusto Lenin Ramírez ( Site 1404) | Ciudad de Guatemala | 01010 | Guatemala | Details | ||
| MEDI-K CAYALA ( Site 1403) | Guatemala | 01016 | Guatemala | Details | ||
| Centro Regional de Sub Especialidades Médicas SA ( Site 1401) | Quetzaltenango | 09001 | Guatemala | Details | ||
| Centro Medico Integral De Cancerología (CEMIC) ( Site 1400) | Quetzaltenango | 09002 | Guatemala | Details | ||
| Bacs-Kiskun Megyei Korhaz-Onkoradiologiai Kozpont ( Site 2102) | Kecskemét | Bacs-Kiskun | 6000 | Hungary | Details | |
| Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház-Onkologiai Kozpont ( Site 2103) | Szolnok | Jasz-Nagykun-Szolnok | 5000 | Hungary | Details | |
| Törökbálinti Tüdőgyógyintézet ( Site 2105) | Törökbálint | Pest | 2045 | Hungary | Details | |
| Semmelweis Egyetem-Pulmonológiai Klinika ( Site 2104) | Budapest | 1083 | Hungary | Details | ||
| Országos Korányi Pulmonológiai Intézet-VI. Tüdöbelosztály és Bronchológia ( Site 2100) | Budapest | 1121 | Hungary | Details | ||
| Fujita Health University ( Site 4406) | Toyoake | Aichi | 470-1192 | Japan | Details | |
| Kurume University Hospital ( Site 4412) | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| Gunma Prefectural Cancer Center ( Site 4416) | Otashi | Gunma | 373-8550 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center ( Site 4415) | Sapporo | Hokkaido | 003-0804 | Japan | Details | |
| Kanagawa Cardiovascular and Respiratory Center ( Site 4404) | Yokohama | Kanagawa | 236-0051 | Japan | Details | |
| Miyagi Cancer Center ( Site 4401) | Natori | Miyagi | 981-1293 | Japan | Details | |
| Sendai Kousei Hospital ( Site 4400) | Sendai | Miyagi | 9800873 | Japan | Details | |
| Kurashiki Central Hospital ( Site 4409) | Kurashiki | Okayama | 710-8602 | Japan | Details | |
| Kansai Medical University Hospital ( Site 4408) | Hirakata | Osaka | 573-1191 | Japan | Details | |
| Osaka Medical and Pharmaceutical University Hospital ( Site 4414) | Takatsuki | Osaka | 569-8686 | Japan | Details | |
| Saitama Prefectural Cancer Center ( Site 4402) | Ina-machi | Saitama | 362-0806 | Japan | Details | |
| Shizuoka Cancer Center ( Site 4405) | Nagaizumi-cho,Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| Tochigi Cancer Center ( Site 4417) | Utsunomiya | Tochigi | 320-0834 | Japan | Details | |
| Juntendo University Hospital ( Site 4413) | Bunkyo-ku | Tokyo | 1138431 | Japan | Details | |
| National Hospital Organization Kyushu Medical Center ( Site 4411) | Fukuoka | 810-8563 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center ( Site 4410) | Fukuoka | 811-1395 | Japan | Details | ||
| Osaka International Cancer Institute ( Site 4407) | Osaka | 541-8567 | Japan | Details | ||
| Nippon Medical School Hospital ( Site 4403) | Tokyo | 113-8603 | Japan | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie-Oddzial Onkologii z Pododdzialem Chemioterapii | Olsztyn | Warminsko-mazurskie | 10-357 | Poland | Details | |
| Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 2801) | Koszalin | Zachodniopomorskie | 75-581 | Poland | Details | |
| SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 2303) | Florești | Cluj | 407280 | Romania | Details | |
| Centrul de Oncologie "Sfântul Nectarie"-Medical Oncology ( Site 2301) | Craiova | Dolj | 200542 | Romania | Details | |
| Cabinet Medical Oncomed ( Site 2305) | Timișoara | Timis | 300239 | Romania | Details | |
| Institutul Oncologic-Oncologie Medicala ( Site 2302) | Cluj | 400015 | Romania | Details | ||
| CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2903) | Port Elizabeth | Eastern Cape | 6055 | South Africa | Details | |
| Medical Oncology Centre of Rosebank ( Site 2907) | Johannesburg | Gauteng | 2196 | South Africa | Details | |
| Steve Biko Academic Hospital-Medical Oncology ( Site 2904) | Pretoria | Gauteng | 0001 | South Africa | Details | |
| Sandton Oncology Medical Group (Pty) Ltd-Research ( Site 2900) | Sandton | Gauteng | 2196 | South Africa | Details | |
| The Oncology Centre ( Site 2901) | Durban | Kwazulu-Natal | 4091 | South Africa | Details | |
| Cape Town Oncology Trials ( Site 2902) | Cape Town | Western Cape | 7570 | South Africa | Details | |
| CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 2404) | Santiago de Compostela | La Coruna | 15706 | Spain | Details | |
| HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 2401) | Madrid | Madrid, Comunidad De | 28009 | Spain | Details | |
| Hospital Universitari Vall d'Hebron-Oncology ( Site 2400) | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Juan Ramon Jimenez-Oncología Medica ( Site 2402) | Huelva | 21005 | Spain | Details | ||
| Changhua Christian Hospital ( Site 4203) | Changhua County | Changhua | 50006 | Taiwan | Details | |
| Chang Gung Memorial Hospital at Kaohsiung ( Site 4200) | Kaohsiung Niao Sung Dist | Kaohsiung | 83301 | Taiwan | Details | |
| National Taiwan University Cancer Center (NTUCC) ( Site 4205) | Taipei City | Taipei | 106 | Taiwan | Details | |
| Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 4207) | Kaohsiung | 807 | Taiwan | Details | ||
| E-Da hospital ( Site 4208) | Kaohsiung | 82445 | Taiwan | Details | ||
| National Cheng Kung University Hospital ( Site 4202) | Tainan | 704 | Taiwan | Details | ||
| National Taiwan University Hospital-Oncology ( Site 4204) | Taipei | 10002 | Taiwan | Details | ||
| Maharaj Nakorn Chiang Mai Hospital ( Site 4300) | Muang | Chiang Mai | 50200 | Thailand | Details | |
| Chulalongkorn University ( Site 4301) | Bangkok | Krung Thep Maha Nakhon | 10330 | Thailand | Details | |
| Division of Medical Oncology, Siriraj H ( Site 4303) | Siriraj | Krung Thep Maha Nakhon | 10700 | Thailand | Details | |
| Songklanagarind hospital ( Site 4302) | Hatyai | Songkhla | 90110 | Thailand | Details | |
| I.E.U. Medical Point Hastanesi-Oncology ( Site 2507) | Izmir, Karsiyaka | Izmir | 009035575 | Turkey | Details | |
| Gulhane Egitim Arastirma Hastanesi-Oncology ( Site 2504) | Ankara | 06010 | Turkey | Details | ||
| Hacettepe Universite Hastaneleri-oncology hospital ( Site 2506) | Ankara | 06230 | Turkey | Details | ||
| Ankara City Hospital-Medical Oncology ( Site 2501) | Ankara | 06800 | Turkey | Details | ||
| TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2502) | Istanbul | 34722 | Turkey | Details | ||
| Memorial Kayseri Hastanesi ( Site 2500) | Kayseri | 38010 | Turkey | Details | ||
| İnönü Üniversitesi Turgut Özal Tıp Merkezi-medical oncology depertmant ( Site 2503) | Malatya | 44280 | Turkey | Details |