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NCT ID NCT06065748
Title A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Hoffmann-La Roche
Age Groups: adult | senior
Covered Countries USA | NZL | ITA | FRA | ESP | DEU | CAN | BEL | AUS

Facility Status City State Zip Country Details
Southern Cancer Center RECRUITING Daphne Alabama 36526 United States Details
Kaiser Permanente - Harbor City RECRUITING Harbor City California 90710 United States Details
USC Norris Comprehensive Cancer Center RECRUITING Los Angeles California 90033 United States Details
USC Norris Cancer Center; Oncology/Hematology - Newport Beach Treatment Center RECRUITING Newport Beach California 92663 United States Details
The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Cente RECRUITING Torrance California 90502 United States Details
Rocky Mountain Cancer Centers RECRUITING Denver Colorado 80220 United States Details
Georgetown University Medical Center RECRUITING Washington District of Columbia 20007 United States Details
MedStar Washington Hosp Center RECRUITING Washington District of Columbia 20010 United States Details
Cancer Specialists of North Florida RECRUITING Jacksonville Florida 32256-6932 United States Details
Grady Health System RECRUITING Atlanta Georgia 30303 United States Details
Winship Cancer Institute of Emory University RECRUITING Atlanta Georgia 30329 United States Details
New England Cancer Specialists RECRUITING Scarborough Maine 04074 United States Details
Maryland Oncology Hematology RECRUITING Annapolis Maryland 21401 United States Details
Frederick Health Hospital RECRUITING Frederick Maryland 21701 United States Details
Dana Farber Cancer Institute RECRUITING Boston Massachusetts 02215 United States Details
Astera Cancer Care East Brunswick RECRUITING East Brunswick New Jersey 08816 United States Details
Oncology Hematology Care RECRUITING Cincinnati Ohio 45242 United States Details
Asante Rogue Regional Medical Center RECRUITING Medford Oregon 97504-8332 United States Details
Ann B. Barshinger Cancer Institute RECRUITING Lancaster Pennsylvania 17604 United States Details
WellSpan Oncology Research RECRUITING York Pennsylvania 17403 United States Details
Avera Cancer Institute - Aberdeen RECRUITING Aberdeen South Dakota 57401 United States Details
Avera Cancer Institute RECRUITING Sioux Falls South Dakota 57105 United States Details
West Cancer Center RECRUITING Germantown Tennessee 38138 United States Details
Texas Oncology Cancer Center RECRUITING Austin Texas 78731 United States Details
Texas Oncology - Baylor Charles A. Sammons Cancer Center RECRUITING Dallas Texas 75246 United States Details
Fundación CENIT para la Investigación en Neurociencias RECRUITING Buenos Aires C1125ABD Argentina Details
Inst. de Oncologia Angel H. Roffo ; Oncology Dept RECRUITING Buenos aires C1417DTB Argentina Details
Centro Oncologico Korben; Oncology RECRUITING Ciudad Autonoma Buenos Aires C1426AGE Argentina Details
Sanatorio Allende RECRUITING Cordoba X5000JHQ Argentina Details
Centro Oncologico Riojano Integral (CORI) RECRUITING La Rioja F5300COE Argentina Details
Hospital Alemán RECRUITING Recoleta C1118AAT Argentina Details
Instituto de Oncología de Rosario RECRUITING Rosario S2000KZE Argentina Details
Sanatorio Parque S.A. RECRUITING Rosario S2000QGB Argentina Details
Hospital Provincial del Centenario RECRUITING Rosario S2002KDS Argentina Details
Centro Oncológico de Excelencia RECRUITING San Juan J5402BGA Argentina Details
Northern Beaches Hospital RECRUITING Frenchs Forest New South Wales 2086 Australia Details
Nepean Hospital; Nepean Cancer Care Centre RECRUITING Kingswood New South Wales 2747 Australia Details
Mater Hospital; Patricia Ritchie Centre for Cancer Care and Research RECRUITING North Sydney New South Wales 2060 Australia Details
University of the Sunshine Coast RECRUITING Sippy Downs Queensland 4556 Australia Details
Mater Misericordiae Limited RECRUITING South Brisbane Queensland 4101 Australia Details
Cancer Research SA RECRUITING Adelaide South Australia 5000 Australia Details
Barwon Health RECRUITING Geelong Victoria 3220 Australia Details
Sunshine Hospital RECRUITING St Albans Victoria 3021 Australia Details
South West Healthcare RECRUITING Warrnambool Victoria 3280 Australia Details
Cliniques Universitaires St-Luc RECRUITING Bruxelles 1200 Belgium Details
UZ Gent RECRUITING Gent 9000 Belgium Details
UZ Leuven Gasthuisberg RECRUITING Leuven 3000 Belgium Details
CHU Sart-Tilman RECRUITING Liège 4000 Belgium Details
Clinique Ste-Elisabeth RECRUITING Namur 5000 Belgium Details
Sint Augustinus Wilrijk RECRUITING Wilrijk 2610 Belgium Details
Obras Sociais Irma Dulce - Osid RECRUITING Salvador BA 40415-006 Brazil Details
Crio - Centro Regional Integrado de Oncologia RECRUITING Fortaleza CE 60336-232 Brazil Details
CEDOES - Diagnóstico e Pesquisa RECRUITING Vitoria ES 29055-450 Brazil Details
Hospital Araujo Jorge; Departamento de Ginecologia E Mama ACTIVE_NOT_RECRUITING Goiania GO 74605-070 Brazil Details
Hospital do Cancer de Pernambuco - HCP RECRUITING Recife PE 50040-000 Brazil Details
Instituto D'Or de Pesquisa e Ensino RECRUITING Rio de Janeiro RJ 22281-100 Brazil Details
Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda RECRUITING Ijui RS 98700-000 Brazil Details
Santa Casa de Misericordia de Porto Alegre ACTIVE_NOT_RECRUITING Porto Alegre RS 90020-090 Brazil Details
Hospital Moinhos de Vento RECRUITING Porto Alegre RS 90035-000 Brazil Details
Hospital Nossa Senhora da Conceicao RECRUITING Porto Alegre RS 90040-373 Brazil Details
Hospital Sao Lucas - PUCRS RECRUITING Porto Alegre RS 90610-000 Brazil Details
Hospital de Cancer de Barretos RECRUITING Barretos SP 14784-400 Brazil Details
Hospital Amaral Carvalho RECRUITING Jau SP 17210-120 Brazil Details
Hospital Sírio-Libanês RECRUITING Sao Paulo SP 01308-050 Brazil Details
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda RECRUITING Sao Paulo SP 01317-001 Brazil Details
Hospital A. C. Camargo; Oncologia RECRUITING Sao Paulo SP 01509-010 Brazil Details
Royal Victoria Regional Health Centre RECRUITING Barrie Ontario L4M 6M2 Canada Details
Lakeridge Health Oshawa RECRUITING Oshawa Ontario L1G 2B9 Canada Details
North York General Hospital RECRUITING Toronto Ontario M2K 1E1 Canada Details
Princess Margaret Cancer Center RECRUITING Toronto Ontario M5G 2M9 Canada Details
CIUSSS du Saguenay Lac-Saint-Jean, Chicoutimi Hospital RECRUITING Chicoutimi Quebec G7H 5H6 Canada Details
CISSS Chaudière-Appalaches RECRUITING Levis Quebec G6V 3Z1 Canada Details
Centre Hospitalier de l'Universite de Montreal (CHUM) RECRUITING Montreal Quebec H2X 0C1 Canada Details
McGill University Health Centre - Glen Site RECRUITING Montreal Quebec H4A 3J1 Canada Details
CHU de Québec - Hôpital du Saint-Sacrement RECRUITING Quebec City Quebec G1S 4L8 Canada Details
Hopital regional de saint jerome RECRUITING Saint-jerome Quebec J7Z 5T3 Canada Details
Clínica Puerto Montt RECRUITING Puerto Montt 5500243 Chile Details
Oncovida RECRUITING Santiago 7510032 Chile Details
Centro De Cancer Universidad Catolica RECRUITING Santiago 8330032 Chile Details
Instituto Nacional del Cancer RECRUITING Santiago 8380000 Chile Details
Icegclinic RECRUITING Santiago Chile Details
Beijing Cancer Hospital RECRUITING Beijing 100142 China Details
the First Hospital of Jilin University; Cancer Center RECRUITING Changchun City 130021 China Details
Hunan Cancer Hospital RECRUITING Changsha CITY 410013 China Details
West China Hospital of Sichuan University RECRUITING Chengdu City 610041 China Details
Sichuan Provincial People's Hospital RECRUITING Chengdu 610072 China Details
The First Affiliated Hospital, Chongqing Medical University RECRUITING Chongqing 400016 China Details
Fujian Medical University Union Hospital RECRUITING Fuzhou City 350001 China Details
No. 900 Hospital (Fuzhou General Hospital) RECRUITING Fuzhou City 350009 China Details
Cancer Center, Sun Yat-sen University of Medical Sciences; Department of Medical Oncology RECRUITING Guangzhou City 510060 China Details
The Second Affiliated Hospital of Zhejiang University College RECRUITING Hangzhou 310009 China Details
Harbin Medical University Cancer Hospital RECRUITING Harbin 150081 China Details
Jinan Central Hospital RECRUITING Jinan City 250013 China Details
Shandong Cancer Hospital RECRUITING Jinan 250117 China Details
The First People's Hospital of Yunnan Province RECRUITING Kunming City 650034 China Details
The First Affiliated Hospital to Henan University of Science and Technology RECRUITING Luoyang City 471031 China Details
Guangxi Cancer Hospital of Guangxi Medical University RECRUITING Nanning City 530021 China Details
Fudan University Shanghai Cancer Center RECRUITING Shanghai City 200120 China Details
Shanxi Province Cancer Hospital RECRUITING Taiyuan City 030013 China Details
Taizhou Hospital of Zhejiang Province RECRUITING Taizhou China Details
Tianjin Cancer Hospital; Department of Breast Oncology RECRUITING Tianjin 300000 China Details
The Tumor Hospital of Xinjiang Medical University RECRUITING Urumqi 830000 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology RECRUITING Wuhan City 430023 China Details
Hubei Cancer Hospital RECRUITING Wuhan 430079 China Details
The Second Affiliated Hospital of Xi'an Jiao Tong University RECRUITING Xi'an City 710004 China Details
Xi'an International Medical Center Hospital RECRUITING Xian 710100 China Details
The Affiliated Hospital of Xuzhou Medical University RECRUITING Xuzhou China Details
Zhejiang Cancer Hospital RECRUITING Zhejiang 310022 China Details
The First Affiliated Hospital of Zhengzhou University RECRUITING Zhengzhou 450052 China Details
Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo RECRUITING Bogota, D.C. 110131 Colombia Details
Oncomedica S.A. RECRUITING Monteria 230002 Colombia Details
Sociedad de Oncología y hematología del Cesar Ltda RECRUITING Valledupar 200001 Colombia Details
Clinica CIMCA RECRUITING San José 10103 Costa Rica Details
ICIMED Instituto de Investigación en Ciencias Médicas RECRUITING San José 10108 Costa Rica Details
Proclinical Pharma RECRUITING San José 11303 Costa Rica Details
Tampere University Hospital RECRUITING Tampere 33520 Finland Details
Institut Sainte Catherine RECRUITING Avignon 84082 France Details
HOPITAL JEAN MINJOZ; Oncologie RECRUITING Besancon 25030 France Details
Centre Francois Baclesse; Comite Sein RECRUITING Caen 14076 France Details
Centre Hospitalier Saint Louis; Oncologie Medicale RECRUITING La Rochelle 17019 France Details
Centre Oscar Lambret; Cancerologie Gynecologique RECRUITING Lille 59020 France Details
Centre Leon Berard; Departement Oncologie Medicale RECRUITING Lyon 69373 France Details
Centre Cancerologie Grand Montpellier RECRUITING Montpellier 34070 France Details
Institut Jean Godinot; Oncologie Medicale RECRUITING Reims CEDEX 51056 France Details
Centre Eugene Marquis; Service d'oncologie RECRUITING Rennes 35042 France Details
IUCT Oncopole RECRUITING Toulouse 31100 France Details
Gustave Roussy RECRUITING Villejuif 94805 France Details
DONAU ISAR Klinikum Deggendorf; Frauenklinik RECRUITING Deggendorf 94469 Germany Details
Gynonco Düsseldorf, MVZ Medical Center GmbH RECRUITING Düsseldorf 40235 Germany Details
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR RECRUITING Freiburg 79110 Germany Details
St. Elisabeth Krankenhaus Köln GmbH; Gynäkologie und Geburtshilfe RECRUITING Koeln 50935 Germany Details
Rotkreuzklinikum München; Frauenklinik RECRUITING Muenchen 80637 Germany Details
Celan S.A. RECRUITING Ciudad de Guatemala 01010 Guatemala Details
INTEGRA Cancer Institute RECRUITING Ciudad de Guatemala 01010 Guatemala Details
Sanatorio MEDIK-Cayala RECRUITING Ciudad de Guatemala 01016 Guatemala Details
Grupo Angeles RECRUITING Guatemala City 01015 Guatemala Details
Oncomedica RECRUITING Guatemala 01010 Guatemala Details
Centro Medico Integral de Cancerologia CEMIC RECRUITING Quetzaltenango 09001 Guatemala Details
Queen Mary Hospital; Dept of Medicine RECRUITING Hong Kong Hong Kong Details
B-A-Z Vármegyei Központi Kórház és Egyetemi Oktatókórház; Klin. Onkológiai és Sugárterápiás Centrum RECRUITING Miskolc 3526 Hungary Details
Nograd Varmegyei Szent Lazar Korhaz; Onkologiai es Sugarterapias Centrum RECRUITING Salgótarján 3100 Hungary Details
MVR Cancer Centre and Research Institute RECRUITING Kozhikode Kerala 673601 India Details
Grant Medical Foundation, Ruby Hall Clinic RECRUITING Pune Maharashtra 411001 India Details
Hadassah Ein Karem Hospital; Oncology Dept RECRUITING Jerusalem 9112000 Israel Details
Rabin Medical Center; Oncology Dept RECRUITING Petah Tikva 4910000 Israel Details
Sheba MC RECRUITING Ramat Gan 5265601 Israel Details
Sourasky Medical Center; Oncology Department RECRUITING Tel-Aviv 6423900 Israel Details
Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialita San Giuseppe Moscati RECRUITING Avellino Campania 83100 Italy Details
Policlinico S.Orsola-Malpighi; Istituto Oncologia R. Addarii RECRUITING Bologna Emilia-Romagna 40138 Italy Details
I.R.S.T Srl IRCCS; Oncologia Medica RECRUITING Meldola Emilia-Romagna 47014 Italy Details
A.O. Universitaria Di Parma RECRUITING Parma Emilia-Romagna 43100 Italy Details
RCCS - Centro di Riferimento; Oncologia Medica B RECRUITING Aviano (PN) Friuli-Venezia Giulia 33081 Italy Details
A.O. Universitaria S. Maria Della Misericordia Di Udine; Oncologia RECRUITING Udine Friuli-Venezia Giulia 33100 Italy Details
Policlinico Universitario Agostino Gemelli RECRUITING Roma Lazio 00168 Italy Details
Università Campus Bio-Medico di Roma; Oncologia Medica RECRUITING Roma Lazio 128 Italy Details
ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica RECRUITING Brescia Lombardia 25123 Italy Details
Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 RECRUITING Milano Lombardia 20133 Italy Details
Istituto Clinico Humanitas;U.O. Oncologia Medica Ed Ematologia RECRUITING Rozzano Lombardia 20089 Italy Details
A.O.U. Maggiore della Carità RECRUITING Novara Piemonte 28100 Italy Details
Presidio Ospedaliero di Summa-Perrino; Oncologia Medica RECRUITING Brindisi Puglia 72100 Italy Details
Humanitas Centro Catanese Di Oncologia; Oncologia Medica RECRUITING Misterbianco (CT) Sicilia 95045 Italy Details
Azienda Ospedaliera Universitaria Careggi RECRUITING Florence Toscana 50134 Italy Details
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II RECRUITING Padova Veneto 35128 Italy Details
Kyungpook National University Chilgok Hospital RECRUITING Daegu 41404 Korea, Republic of Details
Seoul National University Bundang Hospital RECRUITING Seongnam-si 463-707 Korea, Republic of Details
Korea University Anam Hospital RECRUITING Seoul 02841 Korea, Republic of Details
Seoul National University Hospital RECRUITING Seoul 03080 Korea, Republic of Details
Severance Hospital, Yonsei University Health System; Clinical Pharmacy RECRUITING Seoul 03722 Korea, Republic of Details
Asan Medical Center RECRUITING Seoul 05505 Korea, Republic of Details
Gangnam Severance Hospital RECRUITING Seoul 06273 Korea, Republic of Details
Samsung Medical Center ACTIVE_NOT_RECRUITING Seoul 06351 Korea, Republic of Details
Ewha Womans University Mokdong Hospital RECRUITING Seoul 07985 Korea, Republic of Details
Ulsan University Hosiptal RECRUITING Ulsan 44033 Korea, Republic of Details
RENATI INNOVATION S.A.P.I. de C.V RECRUITING Guadalajara Jalisco 44680 Mexico Details
Centro Oncológico Hematológico Roma RECRUITING Mexico City Mexico CITY (federal District) 06700 Mexico Details
Palmerston North Hospital; Regional Cancer Treatment Service RECRUITING Palmerston North 4442 New Zealand Details
Instytut "Centrum Zdrowia Matki Polki"; Klinika Onkologii RECRUITING ?ód? 93-338 Poland Details
Szpital Morski Im. Pck; Oncology & Radiotherapy Dept RECRUITING Gdynia 81-519 Poland Details
Narodowy Instytut Onkologii Odzia? w Gliwicach; Centrum Diagnostyki i Leczenia Chorób Piersi RECRUITING Gliwice 44-102 Poland Details
?wi?tokrzyskie Centrum Onkologii; Dzia? Chemioterapii RECRUITING Kielce 25-734 Poland Details
Przychodnia Lekarska KOMED, Roman Karaszewski RECRUITING Konin 62-500 Poland Details
Szpital Wojewódzki im. Miko?aja Kopernika; Oddzia? Dzienny Chemioterapii RECRUITING Koszalin 75-581 Poland Details
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli; Oddzial Onkologii Klinicznej RECRUITING Lublin 20-090 Poland Details
Mazowiecki Szpital Wojewódzki im. ?w. Jana Paw?a II; Oddzial Onkologii Klinicznej i Radioterapii RECRUITING Siedlce 08-110 Poland Details
Zachodniopomorskie Centrum Onkologii, Osrodek Innowacyjnosci, Rozwoju i Badan Klinicznych RECRUITING Szczecin 71-730 Poland Details
IPO de Coimbra; Servico de Oncologia Medica RECRUITING Coimbra 3000-075 Portugal Details
Hospital de S. Francisco Xavier; Unidade de Oncologia Medica RECRUITING Lisboa 1495-005 Portugal Details
Hospital da Luz; Departamento de Oncologia Medica RECRUITING Lisboa 1500-650 Portugal Details
IPO do Porto; Servico de Oncologia Medica RECRUITING Porto 4200-072 Portugal Details
CHVNG/E_Unidade 1; Servico de Oncologia Medica RECRUITING Vila Nova de Gaia 4434-502 Portugal Details
National Cancer Centre; Medical Oncology RECRUITING Singapore 168583 Singapore Details
Institut Catala d?Oncologia Hospital Germans Trias i Pujol RECRUITING Badalona Barcelona 08916 Spain Details
Hospital Univ Vall d'Hebron; Servicio de Oncologia RECRUITING Sant Andreu de La Barca Barcelona 08740 Spain Details
Hospital de Jerez de la Frontera; Servicio de Oncologia RECRUITING Jerez de La Frontera Cadiz 11407 Spain Details
Hospital Quiron de Madrid; Servicio de Oncologia RECRUITING Pozuelo de Alarcon Madrid 28223 Spain Details
Hospital Universitario Virgen de La Arrixaca; Servicio De Oncologia RECRUITING El Palmar Murcia 30120 Spain Details
Hospital Alvaro Cunqueiro; Servicio de Oncologia RECRUITING Vigo Pontevedra 36213 Spain Details
Hospital Universitari Dexeus - Grupo Quironsalud; Servicio de Oncologia Medica RECRUITING Barcelona 08028 Spain Details
Hospital Juan Ramon Jimenez;Servicio de Oncologia RECRUITING Huelva 21005 Spain Details
Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia RECRUITING Jaen 23007 Spain Details
Centro Oncologico MD Anderson Internacional; Servicio de Oncologia RECRUITING Madrid 28033 Spain Details
Hospital Universitario Virgen Macarena; Servicio de Oncologia RECRUITING Sevilla 41009 Spain Details
Hospital Universitario Virgen del Rocio; Servicio de Oncologia RECRUITING Sevilla 41013 Spain Details
Instituto Valenciano Oncologia; Oncologia Medica RECRUITING Valencia 46009 Spain Details
Hospital Arnau de Vilanova (Valencia) Servicio de Oncologia RECRUITING Valencia 46015 Spain Details
Hsin-Chu Branch of National Taiwan University Hospital RECRUITING Hsinchu City 300 Taiwan Details
China Medical University Hospital; Surgery RECRUITING Taichung 404 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology RECRUITING Taipei City 11259 Taiwan Details
VETERANS GENERAL HOSPITAL; Department of General Surgery RECRUITING Taipei 00112 Taiwan Details
National Taiwan Uni Hospital; Dept of Oncology RECRUITING Taipei 100 Taiwan Details
Veterans General Hospital - Taichung RECRUITING Xitun Dist. 40705 Taiwan Details
Chulabhorn Hospital; Medical Oncology RECRUITING Lak Si 10210 Thailand Details
Maharaj Nakorn Chiang Mai Hospital; Depart of Radiology; Divis of Therapeutic Radiology and Oncology RECRUITING Muang Chiang MAI Delivery Branch 3 50200 Thailand Details
Songklanagarind Hospital; Department of Oncology RECRUITING Songkhla 90110 Thailand Details
*Shaded cells indicate that there was no data available from for the field