Gene Detail

Gene Symbol CDH6
Synonyms CAD6 | KCAD
Gene Description CDH6, cadherin-6, is also known as kidney-cadherin, K-cadherin, and plays a role in mesenchymal-epithelial differentiation of the kidney during embryogenesis (PMID: 2406942). Overexpression of Cdh6 has been observed in osteosarcoma (PMID: 29628305) and may contribute to lymph node metastasis and decreased survival in oral squamous cell carcinoma (PMID: 29805672), however Cdh6 has been demonstrated to have a tumor suppressive function in cholangiocarcinoma (PMID: 27593557).
Entrez Id 1004
Chromosome 5
Map Location 5p13.3
Canonical Transcript NM_004932

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