Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CDH6
Synonyms CAD6 | KCAD
Gene Description CDH6, cadherin-6, is also known as kidney-cadherin, K-cadherin, and plays a role in mesenchymal-epithelial differentiation of the kidney during embryogenesis (PMID: 24069422). Overexpression of Cdh6 has been observed in osteosarcoma (PMID: 29628305) and may contribute to lymph node metastasis and decreased survival in oral squamous cell carcinoma (PMID: 29805672), however Cdh6 has been demonstrated to have a tumor suppressive function in cholangiocarcinoma (PMID: 27593557).


Additional content available in CKB BOOST