Gene Detail

Gene Symbol CDK7
Synonyms CAK | CAK1 | CDKN7 | HCAK | MO15 | p39MO15 | STK1
Gene Description CDK7, cyclin-dependent kinase 7, is a component of the transcription factor IIH (TFIIH) complex, which is involved in transcription and DNA repair (PMID: 29545334, PMID: 28792271). Overexpression of Cdk7 has been observed in a variety of solid tumor types including, triple-negative breast cancer (PMID: 28455421), ER-positive breast cancer (PMID: 27301701), and gastric cancer (PMID: 27562173).
Entrez Id 1022
Chromosome 5
Map Location 5q13.2
Canonical Transcript NM_001799

Additional content available in CKB BOOST