Gene Detail

Gene Symbol CDKN2B
Synonyms CDK4I | INK4B | MTS2 | P15 | p15INK4b | TP15
Gene Description CDKN2B (p27), cyclin-dependent kinase 4 inhibitor B, regulates G1-S phase cell cycle arrest via specific inhibition of CDK4 and CDK6 kinases to function as a tumor suppressor (PMID: 27030077). CDKN2B deletions have been identified in liposarcomas (PMID: 21910158) and renal cell carcinomas (PMID: 23898052).
Entrez Id 1030
Chromosome 9
Map Location 9p21.3
Canonical Transcript NM_004936


Additional content available in CKB BOOST